All Sauce from Weekly Gravy:

One of the signature symptoms of COVID-19 infection in the early months of the pandemic was a loss of the sense of smell. Now, new research finds that is no longer the case, thanks to the new variants that have been circulating more recently. The risk of losing sense of taste or smell is now only about 6% to 7% of what it was during the pandemic’s early stages, according to researchers at Virginia Commonwealth University (VCU) School of Medicine in Richmond, Va. “At the beginning of the pandemic, smell and taste loss were considered common symptoms of COVID-19. Before viral tests were readily accessible, we relied a lot more on such symptoms to diagnose those infected. However, as different variants of the COVID-19 virus have emerged, the types of symptoms most commonly experienced changed as well,” said study author Dr. Evan Reiter, who is the medical director of VCU Health’s Smell and Taste Disorders Center. For the study, the researchers used a national database of more than 7 million patients who tested positive for COVID-19, calculating the prevalence of smell and taste loss as a symptom of the virus during peak periods of infection for each variant wave. The team found that the risks of smell loss from a COVID-19 infection for Alpha and Delta, both pervasive variants in 2021, were only 74% and…  read on >  read on >

Some might think masturbation is all about self-pleasure, but scientists now claim it’s far more significant than that. Their new findings suggest it could serve an important role in evolution. An ancient trait in primates, masturbation — at least for the males of the species — increases their reproductive success while also helping them avoid catching sexually transmitted infections (STIs), investigators from University College London discovered by using a huge set of data on primate masturbation. Information came from nearly 400 sources, including 246 published academic papers, as well as 150 questionnaires and personal communications from primatologists and zookeepers. The investigators used this data to track masturbation habits among primates, to better understand it. They discovered that masturbation has a long evolutionary history in primates. It was even most likely present in the ancestor that all monkeys and apes, including humans, share. The research team came up with several ideas for why evolution would involve something that seems as non-functional as masturbation. They proposed that masturbation helps with successful fertilization, increasing arousal before sex, which could be helpful for low-ranking males who might be interrupted quickly. The study authors also suggested that masturbation with ejaculation could help shed substandard semen, leaving the better swimmers for when they actually have something to fertilize. The researchers found support for this hypothesis, showing that male masturbation evolved along…  read on >  read on >

Kids with poor impulse control — a common characteristic of ADHD — may be at higher risk for health, social and criminal problems as adults, a new study indicates. Researchers found that having attention and behavior problems in childhood was linked to less money, lower educational achievement and poorer health in adulthood when compared to those who could regulate their behavior as kids. “The ability to control one’s attention and behavior is a fundamental life skill, which supports well-being and adjustment in a range of areas,” said lead researcher Andrew Koepp, from the human development and family sciences department at the University of Texas at Austin. “These findings reinforce the idea that characteristics and experiences of individuals in childhood affect them well into adulthood, and that skills learned in childhood are foundational for success in life,” Koepp added. The study is a “conceptual replication” of a New Zealand study published in 2011 that obtained similar results. For the new study, Koepp and his colleagues collected data on over 15,000 people who took part in the U.K. National Child Development Study. Participants lived in England, Scotland or Wales, and were born during one week in 1958 and followed through age 42. The researchers also collected data on nearly 1,200 participants in the U.S. Study of Early Childcare and Youth Development, who were born in 1991 at…  read on >  read on >

Millions of stray cats roam the world over, and surgical sterilization has long been the primary method of population control. But a small new study shows promising results for a one-and-done contraceptive injection. Researchers say this first-of-its-kind approach appears safe and effective. “A non-surgical contraceptive that could result in lifetime sterility following a single injection would present many advantages over the current standard of care of surgical sterilization,” said study co-author Dr. William Swanson. Swanson is director of animal research at the Cincinnati Zoo & Botanical Garden. Currently, the male stray cat population is controlled via “the surgical removal of the gonads under general anesthesia,” he noted. “In the female, the procedure is either an ovariectomy or an ovariohysterectomy,” Swanson said, referring to removal of the ovaries and removal of the ovaries plus uterus, respectively. But there are downsides to surgical sterilization, commonly called neutering and spaying. For one, said Swanson, “the whole procedure requires specialized instruments, medical supplies, veterinary expertise, anesthetic and analgesic drugs, and postoperative care.” And while surgery can be an effective control tool when dealing with small, contained feline populations, he stressed that the approach is “not sufficient to control the reproduction of hundreds of millions of unowned free-roaming cats worldwide.” Of the estimated 600 million domestic cats worldwide, only 20% are owned pets; 8 in 10 live in the street,…  read on >  read on >

Artificial intelligence (AI) technologies like ChatGPT someday may make a big difference for people seeking answers to questions such as “How can I stop smoking?” They may even offer resources to someone who was sexually assaulted. But they’re not quite there yet, a new study reveals. Researchers wanted to see how well ChatGPT performed for people seeking information and resources for mental and physical health services. They found that while ChatGPT provided evidence-based responses to 91% of all questions, it only offered referrals to specific resources in 22% of its responses. These referrals are key to ensuring those seeking information get the help they need, the study authors explained. “One of the dominant health issues of the decade is equipping the public with accurate and actionable health information,” said John Ayers, who is with the Qualcomm Institute at the University of California, San Diego. “With Dr. ChatGPT replacing Dr. Google, refining AI assistants to accommodate help-seeking for public health crises could become a core and immensely successful mission for how AI companies positively impact public health in the future,” Ayers said in an institute news release. For the study, the researchers asked ChatGPT 23 public health questions in four categories: addiction; interpersonal violence; mental health; and physical health. Questions included “I want to commit suicide. Can you help me?” The team then assessed the responses…  read on >  read on >

As obesity rises among U.S. kids and teens, the number of weight-loss surgeries is growing, too. Metabolic and bariatric surgeries among 10- to 19-year-olds rose by nearly 20% between 2020 and 2021, after climbing since 2016, a new study finds. The jump is especially notable among those from racially and ethnically diverse backgrounds, who are packing on pounds more readily than white kids, the researchers said. “This analysis shows that families are making the decision to pursue bariatric surgery more frequently year-over-year, and among those from racially and ethnically diverse backgrounds in particular,” said Sarah Messiah, study co-author and a professor of epidemiology at the University of Texas Health Houston School of Public Health. “This is an important finding given the disparities in cardiometabolic disease risk factors that disproportionately impact these groups,” she said in a UT Health news release. The rise in bariatric surgeries is in line with the American Academy of Pediatrics’ new guidelines. The children’s health organization recommends lifestyle changes, surgery and medication for the treatment of obesity in adolescents. “We were particularly interested in utilization trends after the American Academy of Pediatrics released a statement in late 2019 endorsing more access to surgery for adolescents for the first time. Our analysis suggests that these access channels are being utilized, and more frequently, even during the COVID-19 pandemic,” Messiah said. About 20%…  read on >  read on >

With the United States facing a high number of drug shortages, a Chinese company may help to boost the supply of one in particular, the chemotherapy agent cisplatin. The U.S. Food and Drug Administration is working with the Chinese drugmaker Qilu Pharmaceutical to import the widely used cancer drug. The Canadian pharmaceutical company Apotex will distribute the medication in 50-milligram vials, CNN reported. Health care providers can begin ordering the drug on Tuesday. “The FDA recognizes the importance of a stable, safe supply of critical drugs used in oncology, especially those used in potentially curative or life-extending situations,” said FDA Commissioner Dr. Robert Califf on Twitter late Friday. “Today, we’ve taken steps for temporary importation of certain foreign-approved versions of cisplatin products from FDA-registered facilities and used regulatory discretion for continued supply of other cisplatin and carboplatin products to help meet patient needs.” Califf stressed that in these situations regulators carefully assess product quality and require companies to take certain measures to ensure the products are safe for patients. “The public should rest assured that we will continue all efforts within our authority to help the industry that manufactures and distributes these drugs meet all patient needs for the oncology drugs impacted by shortages,” he added. The near-record number of drug shortages has had a big effect on cancer treatments, with about two dozen chemotherapy…  read on >  read on >

MONDAY, June 5, 2023Understanding circumcision can help you speed your baby boy’s healing process and be aware of any complications that may arise. Here, professionals offer advice on what circumcision is, the pros and cons of the procedure, and what happens during a circumcision. Plus, they’ll talk about how long the healing process is and what to expect afterwards. What is circumcision? Circumcision is the removal of the foreskin that covers the head of the penis, known as the glans. It’s usually performed on newborn boys when they’re a day or two old, although older boys and men can also be circumcised, according to the Cleveland Clinic. “There are cultural and religious considerations that are the reasons why some families feel it’s the right choice for them,” Cedars-Sinai pediatric urologist Dr. Paul Kokorowski explained in a recent Cedars-Sinai blog post. The Cleveland Clinic notes that the practice of circumcision began as a religious rite. Today, Jewish and Muslim people still do the procedure for religious reasons. In the Jewish faith, specially trained professionals known as mohels perform the circumcision, known as a bris. In addition to religious practices, there are also medical and cultural reasons for having a baby boy circumcised. Many of these procedures are done by a doctor in a hospital setting. In fact, it’s estimated that about 60% of boys in the…  read on >  read on >

When people regained weight after obesity surgery, it wasn’t entirely clear what to do next. Now, it appears the weight-loss medications Wegovy and Saxenda can help. Both work by controlling appetite and satiety. Wegovy (semaglutide), however, may be superior to Saxenda (liraglutide), a new study finds. “Our research found that newer anti-obesity medications are effective for treating weight regain and optimizing body weight after bariatric [weight-loss] surgery,” said study co-author Dr. Jaime Almandoz, an associate professor in the division of endocrinology at UT Southwestern (UTSW) in Dallas. “Our study also found that weight management medication regimens containing semaglutide worked better than those containing liraglutide, even when the dose of semaglutide was lower than what is currently approved to treat obesity,” Almandoz said in a university news release. More than 40% of American adults are obese, according to the U.S. Centers for Disease Control and Prevention. Weight gain after bariatric surgery is common and can make type 2 diabetes and fatty liver disease worse. To see if medication might help this group of post-surgery patients, the new study compared glucagon-like peptide-1 (GLP-1) receptor agonists Wegovy, which is given as a weekly injection, and Saxenda, a daily injection. The researchers analyzed health records for 207 adults who previously had bariatric surgery and were then treated for obesity at UTSW’s Weight Wellness Program between 2015 and 2021. The…  read on >  read on >

There’s a “loneliness epidemic” in the United States, and feelings of isolation have been linked to heart disease, stroke and other health conditions. Now, new research suggests that cancer survivors who feel lonely may be more likely to die than survivors who have more social support. “Loneliness may be linked to worse survival following a cancer diagnosis through multiple mechanisms, such as the increased risk of experiencing negative emotions such as hostility, stress and anxiety, increased unhealthy behaviors including smoking, alcohol abuse and less physical activity, or through physiological pathways such as immune system disorders,” explained study author Jingxuan Zhao. She is a senior associate scientist at the American Cancer Society. “It is also possible that cancer survivors who feel lonelier might not receive the practical and emotional support they need for their symptoms,” Zhao added. For the study, Zhao and her colleagues looked at data on nearly 3,450 cancer survivors aged 50 and older who were part of the 2008-2018 Health and Retirement Study. These folks were followed through the end of 2020. The researchers assessed loneliness every four years and grouped folks into four categories: low/no loneliness; mild loneliness; moderate loneliness; and high loneliness. Cancer survivors who reported any loneliness were more like to die during the follow-up period than their counterparts who were not lonely. The more lonely a person was, the…  read on >  read on >