Many Americans most affected by the COVID-19 pandemic don’t believe that racism is associated with poorer health, a nationwide poll shows. The ongoing poll of more than 4,000 lower- and middle-income Americans focuses on communities of color. “It really struck us that — despite the virus’s spread across the country to all types of communities — there’s not a consensus view on the effects of systemic racism,” said lead author Katherine Grace Carman, a senior economist at RAND Corporation. RAND is conducting the poll, with support from the Robert Wood Johnson Foundation. “Respondents see the impact of low incomes and living in a rural community on a person’s health, but race isn’t viewed with the same gravity,” she said in a Robert Wood Johnson news release.Just over 42% of respondents say systemic racism is one of the main reasons people of color have poorer health. About one-third disagree, and about a quarter are neutral. Black respondents are much more likely (69.4%) than white ones (33.2%) to believe that systemic racism affects the health of people of color, according to the poll. Overall, pollsters found a slight increase in respondents’ willingness to risk their own health to return to pre-pandemic “normal.” But respondents who are Black or Hispanic are more likely (68.5%) to be cautious about taking health risks to move about freely than white respondents…  read on >  read on >

When journalist Catherine Guthrie learned that she would need to have a mastectomy following a breast cancer diagnosis, she was shocked by what seemed like a cursory explanation from her surgeon about what would happen next. That included removing both of her breasts, adding implants, and moving a muscle from her back to her chest to make the results look more natural. It didn’t feel right to her. She went home, thought about it and decided to “go flat.” “I feel great about it. I love my body. I love the freedom I have in my body. I love that I have full mobility and strength in my body. I’m as flexible and strong now 10, 11 years later as I was then,” said Guthrie, who already had back issues and had been concerned about how the surgery would impact that. “I absolutely have zero regrets.” Guthrie’s choice mirrors a growing trend: A new study found that a majority of breast cancer patients — 74% — who had opted to “go flat” were satisfied with the outcome. The study, from University of California, Los Angeles (UCLA) Jonsson Comprehensive Cancer Center, also found that 22% of women who responded to the survey had experienced what they refer to as “flat denial,” which is where the surgeon either did not initially offer this choice, didn’t support the…  read on >  read on >

Biomarkers in sperm may help identify men at risk of fathering children with autism, researchers say. For the study, investigators examined sperm epigenetics — the molecular processes that affect gene expression — in 13 men who fathered sons with autism and 13 who had children without the disorder. The American and Spanish researchers focused specifically on DNA methylation, a chemical modification that can turn genes on or off. “We can now potentially use this to assess whether a man is going to pass autism on to his children,” said study co-author Michael Skinner, professor of biological sciences at Washington State University, in Pullman, Wash. “It is also a major step toward identifying what factors might promote autism,” he said in a university news release. The study found 805 different DNA methylation regions that could be epigenetic biomarkers, indicating men more likely to have children with autism. To test their findings about these biomarkers, the researchers used sperm samples from 18 men to see if they could identify those with and without children with autism. The results were 90% accurate, according to the study. But Skinner and his colleagues said more research must be done before this approach can be used in clinical practice. The team is now working on a larger study involving 100 men. “We found out years ago that environmental factors can alter…  read on >  read on >

Many Americans most affected by the COVID-19 pandemic don’t believe that racism is associated with poorer health, a nationwide poll shows. The ongoing poll of more than 4,000 lower- and middle-income Americans focuses on communities of color. “It really struck us that — despite the virus’s spread across the country to all types of communities — there’s not a consensus view on the effects of systemic racism,” said lead author Katherine Grace Carman, a senior economist at RAND Corporation. RAND is conducting the poll, with support from the Robert Wood Johnson Foundation. “Respondents see the impact of low incomes and living in a rural community on a person’s health, but race isn’t viewed with the same gravity,” she said in a Robert Wood Johnson news release.Just over 42% of respondents say systemic racism is one of the main reasons people of color have poorer health. About one-third disagree, and about a quarter are neutral. Black respondents are much more likely (69.4%) than white ones (33.2%) to believe that systemic racism affects the health of people of color, according to the poll. Overall, pollsters found a slight increase in respondents’ willingness to risk their own health to return to pre-pandemic “normal.” But respondents who are Black or Hispanic are more likely (68.5%) to be cautious about taking health risks to move about freely than white respondents…  read on >  read on >

When journalist Catherine Guthrie learned that she would need to have a mastectomy following a breast cancer diagnosis, she was shocked by what seemed like a cursory explanation from her surgeon about what would happen next. That included removing both of her breasts, adding implants, and moving a muscle from her back to her chest to make the results look more natural. It didn’t feel right to her. She went home, thought about it and decided to “go flat.” “I feel great about it. I love my body. I love the freedom I have in my body. I love that I have full mobility and strength in my body. I’m as flexible and strong now 10, 11 years later as I was then,” said Guthrie, who already had back issues and had been concerned about how the surgery would impact that. “I absolutely have zero regrets.” Guthrie’s choice mirrors a growing trend: A new study found that a majority of breast cancer patients — 74% — who had opted to “go flat” were satisfied with the outcome. The study, from University of California, Los Angeles (UCLA) Jonsson Comprehensive Cancer Center, also found that 22% of women who responded to the survey had experienced what they refer to as “flat denial,” which is where the surgeon either did not initially offer this choice, didn’t support the…  read on >  read on >

Biomarkers in sperm may help identify men at risk of fathering children with autism, researchers say. For the study, investigators examined sperm epigenetics — the molecular processes that affect gene expression — in 13 men who fathered sons with autism and 13 who had children without the disorder. The American and Spanish researchers focused specifically on DNA methylation, a chemical modification that can turn genes on or off. “We can now potentially use this to assess whether a man is going to pass autism on to his children,” said study co-author Michael Skinner, professor of biological sciences at Washington State University, in Pullman, Wash. “It is also a major step toward identifying what factors might promote autism,” he said in a university news release. The study found 805 different DNA methylation regions that could be epigenetic biomarkers, indicating men more likely to have children with autism. To test their findings about these biomarkers, the researchers used sperm samples from 18 men to see if they could identify those with and without children with autism. The results were 90% accurate, according to the study. But Skinner and his colleagues said more research must be done before this approach can be used in clinical practice. The team is now working on a larger study involving 100 men. “We found out years ago that environmental factors can alter…  read on >  read on >

There’s yet another reason to quit smoking: It increases the risk of deadly bleeding strokes, a new study warns. Researchers focused on a type of stroke called subarachnoid hemorrhage (SAH), which occurs when a blood vessel on the surface of the brain ruptures and bleeds into the space between the brain and the skull. This type of stroke mainly affects middle-aged adults and has high rates of complications and death. In this study, researchers analyzed genetic data gathered from more than 408,000 people, ages 40-69, in the United Kingdom between 2006 and 2010. During that time, more than 900 of these strokes occurred. The more people smoked, the greater their risk of SAH. Compared to those who didn’t smoke, those who smoked half a pack to 20 packs of cigarettes a year had a 27% higher risk. Those who smoked more than 40 packs of cigarettes a year had a nearly three times greater risk, according to the findings. The researchers also found that people who were genetically predisposed to smoking — as determined by the researchers’ scoring system — had a 63% increased risk, according to the study. The results were published Jan. 14 in the journal Stroke. “Previous studies have shown that smoking is associated with higher risks of SAH, yet it has been unclear if smoking or another confounding condition such as…  read on >  read on >

Two types of air pollution declined in cities around the world during initial COVID-19 lockdowns, but one type increased, a new study finds. Researchers assessed changes in levels of nitrogen dioxide, ozone and fine particulate (PM2.5) air pollution during lockdowns in 11 cities: Beijing and Wuhan in China; Milan; Rome; Madrid; London; Paris; Berlin; New York; Los Angeles; and Delhi, India. After accounting for weather effects, the researchers found that reductions in nitrogen dioxide were smaller than anticipated, while ozone concentrations rose. Nitrogen dioxide is a major air pollutant from vehicle emissions, and is associated with respiratory problems. Ozone is also harmful to health and damages crops, the study authors noted. In addition, the researchers found that PM2.5 concentrations dropped during lockdowns in all cities but London and Paris. PM2.5 can worsen health problems such as asthma and heart disease. The findings were published Jan. 13 in the journal Science Advances. Lead author Zongbo Shi, a professor of atmospheric biogeochemistry at the University of Birmingham in the United Kingdom, said the rapid reduction in economic activity provided a unique opportunity to study the impact of interventions on air quality. “Emission changes associated with the early lockdown restrictions led to abrupt changes in air pollutant levels but their impacts on air quality were more complex than we thought, and smaller than we expected,” he said in…  read on >  read on >