Microbes that live in a child’s upper airway could be linked to severe asthma attacks, new research suggests. For parents, it’s an all-too familiar scene: A child’s seemingly harmless cough quickly escalates to wheezing, gasping and an urgent need for emergency treatment. Asthma is the leading chronic disease in kids and third-most common cause of hospitalization among those under 15, according to the Asthma and Allergy Foundation of America. Now, a new study found an association between asthma flare-ups in children and the makeup of the upper-airway microbiome, communities of microscopic organisms that include bacteria. “In the future, we wish to understand whether the upper-airway bacteria can play a causal role in the severity of asthma symptoms,” said study author Dr. Yanjiao Zhou, who conducted the research at Washington University School of Medicine in St. Louis. She is now an assistant professor of medicine at UConn Health in Farmington, Conn. Zhou and her colleagues collected data on 214 school-aged children who were part of a clinical trial. Participants had mild to moderate asthma that was being treated with daily inhaled corticosteroids. Nasal samples were collected twice — once when asthma was under control, and again when kids had the signs of an emerging flare-up, what the investigators called the “yellow zone.” The researchers said kids who had early warning signs of a flare-up were more…  read on >

If your child is obese, new research suggests that those extra pounds can alter the results of routine blood tests. “We performed the first comprehensive analysis of the effect of obesity on routine blood tests in a large community population of children and found that almost 70% of the blood tests studied were affected,” said study first author Victoria Higgins, from the Hospital for Sick Children in Toronto and the University of Toronto. Higgins’ team looked at more than 1,300 healthy children and teens in and around Toronto and found that obesity affected 24 routine blood tests, including those for liver function, inflammation markers, lipids and iron. The study was published Dec. 17 in the Journal of Clinical Endocrinology & Metabolism. “As clinical decisions are often guided by normative ranges based on a large healthy population, understanding how and which routine blood tests are affected by obesity is important to correctly interpret blood test results,” Higgins explained in a journal news release. It’s unclear if obesity’s impact on blood tests are a sign of early disease, but doctors should be aware of these findings when interpreting several types of blood tests in children, the researchers advised. “We hope our study results will assist pediatricians and family physicians to better assess children and adolescents with different degrees of overweight or obesity,” Higgins said. There’s been a…  read on >