Natural immunity acquired from a COVID infection provides strong and lasting protection against severe illness if a person becomes reinfected, a new evidence review has concluded. Ten months after a COVID infection, protection against hospitalization and death remains at 89% for Omicron and 90% for earlier variants, according to pooled data from 65 studies conducted in 19 countries. However, protection against reinfection wanes quickly with Omicron, which is the dominant COVID strain at this time, researchers found. After 10 months, a previous case of Omicron provides only 36% protection against a follow-up COVID infection, researchers reported Feb. 16 in The Lancet. The analysis suggests that the level and duration of protection derived from COVID infection is at least on a par with that provided by two doses of the mRNA vaccines developed by Moderna and Pfizer-BioNTech, researchers said. “These findings are not surprising as multiple studies have shown that prior infection confers protection against severe disease, though it may not confer protection against infection in the Omicron era,” said Dr. Amesh Adalja, a senior scholar with the Johns Hopkins Center for Health Security in Baltimore. He was not involved in the research. But because people first infected with the coronavirus run the risk of hospitalization, death and long COVID, researchers concluded that vaccination remains the overall best form of protection against COVID. “The vaccines and…  read on >  read on >

Older people have vaccines available to prevent severe influenza and COVID-19, but there’s been nothing to protect against the third respiratory virus that contributed to this season’s wretched “triple-demic.” Until now. Two major pharmaceutical companies published clinical trial results this week that pave the way for an RSV (respiratory syncytial virus) vaccine to be available for adults by the time next cold and flu season rolls around. “RSV continues to be the last of the major winter respiratory viruses for which we don’t have a vaccine, but as these two articles in the New England Journal of Medicine indicate, we’re getting close,” said Dr. William Schaffner. He is medical director of the National Foundation for Infectious Diseases, in Bethesda, Md. The companies — GlaxoSmithKline (GSK) and Janssen — both have RSV vaccine candidates that can prevent severe illness in seniors, results show. The GSK vaccine provides 94% protection against severe lower respiratory tract RSV, and about 83% protection against lower respiratory tract infections overall, said Dr. Leonard Friedland, vice president and director of scientific affairs and public health for GSK U.S. Vaccines. “We’re very, very pleased and excited because this is the first time that an RSV vaccine has made it through phase 3 and has published data in a peer-reviewed journal,” Friedland said. The Janssen vaccine also provided good protection in a phase 2b…  read on >  read on >

Talk about the stuff of nightmares. You have extremely itchy skin at bedtime, not to mention a pimple-like rash. What is it? Those are fairly clear signs of scabies, a microscopic parasitic infestation where mites burrow under your skin and lay eggs there. Scabies infection comes from prolonged contact, not just a quick brush against someone else’s skin. It can also be passed through bedding or clothing. “Anyone who is diagnosed with scabies, as well as his or her sexual partners and other contacts who have had prolonged skin-to-skin contact with the infested person, should be treated,” the U.S. Centers for Disease Control and Prevention advises. What is scabies? This “human itch mite” lives and lays eggs in the upper layer of the skin, according to the CDC. About 200 million people worldwide have scabies at any one time, including up to 10% of children in poor areas, according to the World Health Organization. Once the eggs hatch, the larvae can travel to the skin’s surface, spreading to other areas or other people, according to the Mayo Clinic. What does scabies look like? It may resemble hives, tiny bites, knots under the skin or even eczema-like scaly patches, according to the American Academy of Dermatology (AAD). Sores may develop from scratching. Under magnification, the mite is creamy-white, has eight legs and a round body. It…  read on >  read on >

Ramen danger: A steaming cup of instant noodles is a big cause of scald injuries in children, researchers report. A new study that examined pediatric admissions at University of Chicago Medicine for burn injuries caused by hot liquids found that nearly one-third were caused by instant noodles between 2010 and 2020. “Anecdotally, it felt like every other child we were consulted on for a burn was injured by instant noodles, so we wanted to dive into the data to see what the trend really was,” said senior author Dr. Sebastian Vrouwe, assistant professor of surgery at UChicago Medicine. “Our hope is to develop the groundwork for future burn prevention programming, as essentially all childhood burns are in some way preventable,” he said in a system news release. Researchers from the UChicago Medicine’s Burn Center reviewed 790 cases, attributing 31% to instant noodles. The research team also found that Black children and kids who lived in areas with lower Childhood Opportunity Index (COI) scores were more likely to suffer these scald burns than their peers. Broadly stated, the COI is a measure of social, economic, educational and health conditions in neighborhoods. Being unsupervised led to higher risk. About 40% of instant noodle burns occurred when kids were alone. While the study examined only data from UChicago Medicine’s Burn Center, researchers suspect the statistics speak to a…  read on >  read on >

A highly infectious strain of avian influenza is tearing through commercial and backyard poultry flocks, causing egg prices to rise as sick chickens are culled across the United States. Now, some experts are worried that the H5N1 avian flu might become humankind’s next pandemic-causing pathogen, if the raging virus makes the leap from birds to humans. That’s because other mammals have started to pick up the avian flu, and mammal-to-mammal outbreaks of the H5N1 virus are also occurring in rare instances. “We’re always concerned when it’s in mammals, just because they’re closely related to humans,” explained Dr. Ryan Miller, an infectious disease doctor at the Cleveland Clinic, in Ohio. The red flag officially unfurled last week in a report published in the Journal of the American Medical Association, which noted the spread of avian flu into certain mink and seal populations, and assessed the threat of spread into humans. “During the past 20 years, fewer than 900 confirmed human cases of H5N1 have been reported to the WHO [World Health Organization],” the report stated. “The historic case-fatality rate for human H5N1 infection has been high — more than 50%. But some experts say that’s likely an overestimation because many mild or asymptomatic infections may go unreported.” “Lots of flu viruses circulate in birds but never pose major threats to humans,” Dr. Amesh Adalja, a senior…  read on >  read on >

In 2021, U.S. emergency rooms treated more than 193,000 burn injuries caused by an array of products, ranging from cooking devices to fireworks and space heaters. Most of these burns were preventable, according to the Consumer Product Safety Commission. Children under age 10 are especially vulnerable, accounting for 26% of all burn injuries in 2021, according to a commission news release. Here, the CPSC offers some tips for staying safe from burns: Keep children away from the cooking area. Keep flammable items, such as potholders and bags, away from the stove and oven. Keep clothing away from flames or ignition sources. Loose clothing can catch fire easily. Leave at least 3 feet between a space heater and a person. Keep hands and fingers away from it. Don’t leave loose flammable items near it. Don’t smoke while drowsy, and use flashlights instead of candles. If you do use candles, don’t burn them near anything that can catch fire and never leave them unattended. Always extinguish candles before leaving the room or going to sleep. If your clothing does catch fire, immediately stop. Don’t run. Drop to the ground and roll. Cover your face. Roll until the fire is out, the U.S. Centers for Disease Control and Prevention and the National Fire Prevention Association advised. If you’re not able to drop, use something like a blanket to…  read on >  read on >

For the first time, COVID-19 vaccines have been added to the list of routine immunizations recommended for adults — a further sign the virus is here to stay. The addition is being made to the 2023 Recommended Adult Immunization Schedule, released Thursday by the Advisory Committee on Immunization Practice (ACIP), an expert panel that advises the U.S. federal government on vaccination recommendations for all Americans. COVID vaccination has, of course, been recommended ever since the vaccines became available. But its inclusion on the recommended vaccine schedule underscores the fact that COVID-19 is not going away, said Dr. Sandra Adamson Fryhofer, an Atlanta-based physician who serves as an ACIP liaison. “This reiterates that COVID has gone from pandemic to endemic,” Fryhofer said. “For now, it looks like it’s here to stay.” “Endemic” means that a disease is spreading at a more stable frequency, versus the exponential growth seen during a pandemic. At this point, most Americans have received the primary series of vaccines against COVID. However, few have gotten the updated “bivalent” boosters that target both the original strain of the virus that causes COVID and two Omicron subvariants. It has been available since September, but only about 16% of Americans have gotten it, according to the U.S. Centers for Disease Control and Prevention. That rate is higher among people age 65 and older, who are…  read on >  read on >