They’re medical miracles: A new report finds that vaccines against 10 major diseases prevented 37 million deaths between 2000 and 2019 in low- and middle-income countries worldwide, with young children benefiting most. Vaccinations are also projected to prevent a total of 69 million deaths between 2000 and 2030, researchers say. Their modeling study also shows that vaccination against the 10 diseases — including measles, rotavirus, HPV and hepatitis B — means that people born in 2019 will have a 72% lower risk of death from those diseases over their lifetime. “There has been a much-needed investment in childhood vaccination programs in low-income and middle-income countries [LMICs] and this has led to an increase in the number of children vaccinated,” explained study co-author Caroline Trotter, an infectious diseases researcher at the University of Cambridge in the U.K. The greatest benefit of vaccination is among children under age 5. In this age group, deaths from the 10 diseases would be 45% higher without vaccination, according to findings published Jan. 29 inThe Lancet medical journal. Vaccinations against measles will have the biggest impact, preventing 56 million deaths between 2000 and 2030. Over the lifetime of people born between those years, vaccination will prevent 120 million deaths — 65 million of them in kids under age 5. The study assessed vaccination programs in 98 countries. Other pathogens studied were…  read on >  read on >

They’re medical miracles: A new report finds that vaccines against 10 major diseases prevented 37 million deaths between 2000 and 2019 in low- and middle-income countries worldwide, with young children benefiting most. Vaccinations are also projected to prevent a total of 69 million deaths between 2000 and 2030, researchers say. Their modeling study also shows that vaccination against the 10 diseases — including measles, rotavirus, HPV and hepatitis B — means that people born in 2019 will have a 72% lower risk of death from those diseases over their lifetime. “There has been a much-needed investment in childhood vaccination programs in low-income and middle-income countries [LMICs] and this has led to an increase in the number of children vaccinated,” explained study co-author Caroline Trotter, an infectious diseases researcher at the University of Cambridge in the U.K. The greatest benefit of vaccination is among children under age 5. In this age group, deaths from the 10 diseases would be 45% higher without vaccination, according to findings published Jan. 29 inThe Lancet medical journal. Vaccinations against measles will have the biggest impact, preventing 56 million deaths between 2000 and 2030. Over the lifetime of people born between those years, vaccination will prevent 120 million deaths — 65 million of them in kids under age 5. The study assessed vaccination programs in 98 countries. Other pathogens studied were…  read on >  read on >

They’re medical miracles: A new report finds that vaccines against 10 major diseases prevented 37 million deaths between 2000 and 2019 in low- and middle-income countries worldwide, with young children benefiting most. Vaccinations are also projected to prevent a total of 69 million deaths between 2000 and 2030, researchers say. Their modeling study also shows that vaccination against the 10 diseases — including measles, rotavirus, HPV and hepatitis B — means that people born in 2019 will have a 72% lower risk of death from those diseases over their lifetime. “There has been a much-needed investment in childhood vaccination programs in low-income and middle-income countries [LMICs] and this has led to an increase in the number of children vaccinated,” explained study co-author Caroline Trotter, an infectious diseases researcher at the University of Cambridge in the U.K. The greatest benefit of vaccination is among children under age 5. In this age group, deaths from the 10 diseases would be 45% higher without vaccination, according to findings published Jan. 29 inThe Lancet medical journal. Vaccinations against measles will have the biggest impact, preventing 56 million deaths between 2000 and 2030. Over the lifetime of people born between those years, vaccination will prevent 120 million deaths — 65 million of them in kids under age 5. The study assessed vaccination programs in 98 countries. Other pathogens studied were…  read on >  read on >

They’re medical miracles: A new report finds that vaccines against 10 major diseases prevented 37 million deaths between 2000 and 2019 in low- and middle-income countries worldwide, with young children benefiting most. Vaccinations are also projected to prevent a total of 69 million deaths between 2000 and 2030, researchers say. Their modeling study also shows that vaccination against the 10 diseases — including measles, rotavirus, HPV and hepatitis B — means that people born in 2019 will have a 72% lower risk of death from those diseases over their lifetime. “There has been a much-needed investment in childhood vaccination programs in low-income and middle-income countries [LMICs] and this has led to an increase in the number of children vaccinated,” explained study co-author Caroline Trotter, an infectious diseases researcher at the University of Cambridge in the U.K. The greatest benefit of vaccination is among children under age 5. In this age group, deaths from the 10 diseases would be 45% higher without vaccination, according to findings published Jan. 29 inThe Lancet medical journal. Vaccinations against measles will have the biggest impact, preventing 56 million deaths between 2000 and 2030. Over the lifetime of people born between those years, vaccination will prevent 120 million deaths — 65 million of them in kids under age 5. The study assessed vaccination programs in 98 countries. Other pathogens studied were…  read on >  read on >

Just one dose of Pfizer’s coronavirus vaccine might be enough to largely protect people from being infected with COVID-19, preliminary research shows. The vaccine became 90% effective 21 days after the first shot in a two-dose regimen, said British researchers who looked at data from Israel, where the vaccine has been rolled out to a large portion of the population. “A second dose of the Pfizer vaccine would normally be given 21 days or more after the first, to top up and lengthen the effect of the first dose,” explained lead researcher Paul Hunter, from the University of East Anglia’s Norwich Medical School. “But here in the U.K., the decision was made to delay the timing of the second injection until 12 weeks after the first,” Hunter said in a university news release. “The logic behind this is to protect more people sooner and so reduce the total number of severe infections, hospitalizations and deaths,” Hunter explained. “But this decision caused criticism from some quarters, due in part to a belief that a single injection may not give adequate immunity.” Hunter noted that an earlier study, which has not been peer-reviewed, reported that a single shot of the Pfizer vaccine might not provide sufficient protection. “But we saw a number of flaws in how they looked at the data, including the fact that they did…  read on >  read on >

Joe DiMeo’s life changed forever when he fell asleep at the wheel on U.S. Route 22 in New Jersey on July 14, 2018. The horrific crash left him with third-degree burns on 80% of his body and a grim prognosis. Now, more than two years later, DiMeo, 22, is the recipient of the world’s first successful double hand and face transplant, and on the road to recovery. The historic surgery, which took place on Aug. 12, 2020, at NYU Langone in New York City, involved more than 140 health care professionals. Over 23 hours, they successfully transplanted two hands, three dominant nerves to the hand, six blood vessels, 21 tendons and a full face, including forehead, eyebrows, both ears, nose, eyelids, lips, and underlying skull, cheek, nasal and chin bone segments. Face and hand transplants have been performed independently, but this double procedure had been attempted twice before and was unsuccessful both times. For this procedure, surgeons used computer-generated three-dimensional guides. They ensured that bones were properly aligned and implants were in position to anchor the grafted face and hands to DiMeo. Technology aside, a big part of DiMeo’s success owes to his can-do attitude, according to the head of his surgical team, Dr. Eduardo Rodriguez, director of NYU Langone’s Face Transplant Program. “He is the most highly motivated patient I have ever met,” Rodriguez…  read on >  read on >

Just one dose of Pfizer’s coronavirus vaccine might be enough to largely protect people from being infected with COVID-19, preliminary research shows. The vaccine became 90% effective 21 days after the first shot in a two-dose regimen, said British researchers who looked at data from Israel, where the vaccine has been rolled out to a large portion of the population. “A second dose of the Pfizer vaccine would normally be given 21 days or more after the first, to top up and lengthen the effect of the first dose,” explained lead researcher Paul Hunter, from the University of East Anglia’s Norwich Medical School. “But here in the U.K., the decision was made to delay the timing of the second injection until 12 weeks after the first,” Hunter said in a university news release. “The logic behind this is to protect more people sooner and so reduce the total number of severe infections, hospitalizations and deaths,” Hunter explained. “But this decision caused criticism from some quarters, due in part to a belief that a single injection may not give adequate immunity.” Hunter noted that an earlier study, which has not been peer-reviewed, reported that a single shot of the Pfizer vaccine might not provide sufficient protection. “But we saw a number of flaws in how they looked at the data, including the fact that they did…  read on >  read on >

Joe DiMeo’s life changed forever when he fell asleep at the wheel on U.S. Route 22 in New Jersey on July 14, 2018. The horrific crash left him with third-degree burns on 80% of his body and a grim prognosis. Now, more than two years later, DiMeo, 22, is the recipient of the world’s first successful double hand and face transplant, and on the road to recovery. The historic surgery, which took place on Aug. 12, 2020, at NYU Langone in New York City, involved more than 140 health care professionals. Over 23 hours, they successfully transplanted two hands, three dominant nerves to the hand, six blood vessels, 21 tendons and a full face, including forehead, eyebrows, both ears, nose, eyelids, lips, and underlying skull, cheek, nasal and chin bone segments. Face and hand transplants have been performed independently, but this double procedure had been attempted twice before and was unsuccessful both times. For this procedure, surgeons used computer-generated three-dimensional guides. They ensured that bones were properly aligned and implants were in position to anchor the grafted face and hands to DiMeo. Technology aside, a big part of DiMeo’s success owes to his can-do attitude, according to the head of his surgical team, Dr. Eduardo Rodriguez, director of NYU Langone’s Face Transplant Program. “He is the most highly motivated patient I have ever met,” Rodriguez…  read on >  read on >

Many young Americans are prescribed psychiatric drugs to treat medical conditions, but nearly one-third of them wind up misusing the medications, a new study finds. “Misuse of prescription substances is alarmingly high among U.S. youth and young adults,” said lead researcher Israel Agaku, a part-time lecturer in oral health policy and epidemiology at the Harvard School of Dental Medicine, in Boston. The study found that, overall, 35% of young people (aged 12 to 25) said they had taken a prescribed psychoactive drug in the past year, and 31% of those said they had misused that drug. While opioids were the most commonly prescribed drug, misuse of stimulants and tranquilizers was higher. Psychotropic drugs change a person’s mental state and can have intoxicating effects. “This study draws attention to the silent epidemic of prescription stimulant use among youth,” Agaku said. “With increasing popularity of performance-enhancing stimulants in schools, it is imperative for policymakers, school administrators, health care professionals and parents to become more aware of this emerging danger and take appropriate steps, similar to what has been done for the opioid epidemic.” Dr. Scott Krakower, an attending psychiatrist in child and adolescent psychiatry at Zucker Hillside Hospital in Glen Oaks, N.Y., said, “It is very alarming to see so many young people having access to controlled substances.” It is important for doctors to screen for illicit…  read on >  read on >

The great outdoors can soothe the soul, but new research suggests that working outside might also guard against breast cancer. The study wasn’t designed to say how working outside affects chances of developing breast cancer, but vitamin D exposure may be the driving force, the researchers suggested. “The main hypothesis is that sun exposure through vitamin D production may decrease the risk of breast cancer after age 50,” said study author Julie Elbaek Pedersen, of the Danish Cancer Society Research Center in Copenhagen. Vitamin D deficiency has been linked to a host of diseases and conditions including breast cancer. Vitamin D is often called the “sunshine vitamin” because your body produces it when exposed to the sun’s ultraviolet B rays. The body mainly makes vitamin D in the middle of the working day so outdoor workers are exposed to considerably higher levels than those who work indoors, Pedersen said. “Women who work outdoors may regularly be exposed to sunlight and thereby have more sufficient long-term levels of vitamin D compared with women working indoors,” she said. You don’t need much sun exposure to make adequate amounts of D. “Maximum daily vitamin D levels are secured after only minutes in the sun in the summertime, and more time will not increase the levels further,” Pedersen said. In recent years, the push to wear sunscreen and avoid…  read on >  read on >