They’re medical miracles: A new report finds that vaccines against 10 major diseases prevented 37 million deaths between 2000 and 2019 in low- and middle-income countries worldwide, with young children benefiting most. Vaccinations are also projected to prevent a total of 69 million deaths between 2000 and 2030, researchers say. Their modeling study also shows that vaccination against the 10 diseases — including measles, rotavirus, HPV and hepatitis B — means that people born in 2019 will have a 72% lower risk of death from those diseases over their lifetime. “There has been a much-needed investment in childhood vaccination programs in low-income and middle-income countries [LMICs] and this has led to an increase in the number of children vaccinated,” explained study co-author Caroline Trotter, an infectious diseases researcher at the University of Cambridge in the U.K. The greatest benefit of vaccination is among children under age 5. In this age group, deaths from the 10 diseases would be 45% higher without vaccination, according to findings published Jan. 29 inThe Lancet medical journal. Vaccinations against measles will have the biggest impact, preventing 56 million deaths between 2000 and 2030. Over the lifetime of people born between those years, vaccination will prevent 120 million deaths — 65 million of them in kids under age 5. The study assessed vaccination programs in 98 countries. Other pathogens studied were…  read on >  read on >

They’re medical miracles: A new report finds that vaccines against 10 major diseases prevented 37 million deaths between 2000 and 2019 in low- and middle-income countries worldwide, with young children benefiting most. Vaccinations are also projected to prevent a total of 69 million deaths between 2000 and 2030, researchers say. Their modeling study also shows that vaccination against the 10 diseases — including measles, rotavirus, HPV and hepatitis B — means that people born in 2019 will have a 72% lower risk of death from those diseases over their lifetime. “There has been a much-needed investment in childhood vaccination programs in low-income and middle-income countries [LMICs] and this has led to an increase in the number of children vaccinated,” explained study co-author Caroline Trotter, an infectious diseases researcher at the University of Cambridge in the U.K. The greatest benefit of vaccination is among children under age 5. In this age group, deaths from the 10 diseases would be 45% higher without vaccination, according to findings published Jan. 29 inThe Lancet medical journal. Vaccinations against measles will have the biggest impact, preventing 56 million deaths between 2000 and 2030. Over the lifetime of people born between those years, vaccination will prevent 120 million deaths — 65 million of them in kids under age 5. The study assessed vaccination programs in 98 countries. Other pathogens studied were…  read on >  read on >

They’re medical miracles: A new report finds that vaccines against 10 major diseases prevented 37 million deaths between 2000 and 2019 in low- and middle-income countries worldwide, with young children benefiting most. Vaccinations are also projected to prevent a total of 69 million deaths between 2000 and 2030, researchers say. Their modeling study also shows that vaccination against the 10 diseases — including measles, rotavirus, HPV and hepatitis B — means that people born in 2019 will have a 72% lower risk of death from those diseases over their lifetime. “There has been a much-needed investment in childhood vaccination programs in low-income and middle-income countries [LMICs] and this has led to an increase in the number of children vaccinated,” explained study co-author Caroline Trotter, an infectious diseases researcher at the University of Cambridge in the U.K. The greatest benefit of vaccination is among children under age 5. In this age group, deaths from the 10 diseases would be 45% higher without vaccination, according to findings published Jan. 29 inThe Lancet medical journal. Vaccinations against measles will have the biggest impact, preventing 56 million deaths between 2000 and 2030. Over the lifetime of people born between those years, vaccination will prevent 120 million deaths — 65 million of them in kids under age 5. The study assessed vaccination programs in 98 countries. Other pathogens studied were…  read on >  read on >

Just one dose of Pfizer’s coronavirus vaccine might be enough to largely protect people from being infected with COVID-19, preliminary research shows. The vaccine became 90% effective 21 days after the first shot in a two-dose regimen, said British researchers who looked at data from Israel, where the vaccine has been rolled out to a large portion of the population. “A second dose of the Pfizer vaccine would normally be given 21 days or more after the first, to top up and lengthen the effect of the first dose,” explained lead researcher Paul Hunter, from the University of East Anglia’s Norwich Medical School. “But here in the U.K., the decision was made to delay the timing of the second injection until 12 weeks after the first,” Hunter said in a university news release. “The logic behind this is to protect more people sooner and so reduce the total number of severe infections, hospitalizations and deaths,” Hunter explained. “But this decision caused criticism from some quarters, due in part to a belief that a single injection may not give adequate immunity.” Hunter noted that an earlier study, which has not been peer-reviewed, reported that a single shot of the Pfizer vaccine might not provide sufficient protection. “But we saw a number of flaws in how they looked at the data, including the fact that they did…  read on >  read on >

Joe DiMeo’s life changed forever when he fell asleep at the wheel on U.S. Route 22 in New Jersey on July 14, 2018. The horrific crash left him with third-degree burns on 80% of his body and a grim prognosis. Now, more than two years later, DiMeo, 22, is the recipient of the world’s first successful double hand and face transplant, and on the road to recovery. The historic surgery, which took place on Aug. 12, 2020, at NYU Langone in New York City, involved more than 140 health care professionals. Over 23 hours, they successfully transplanted two hands, three dominant nerves to the hand, six blood vessels, 21 tendons and a full face, including forehead, eyebrows, both ears, nose, eyelids, lips, and underlying skull, cheek, nasal and chin bone segments. Face and hand transplants have been performed independently, but this double procedure had been attempted twice before and was unsuccessful both times. For this procedure, surgeons used computer-generated three-dimensional guides. They ensured that bones were properly aligned and implants were in position to anchor the grafted face and hands to DiMeo. Technology aside, a big part of DiMeo’s success owes to his can-do attitude, according to the head of his surgical team, Dr. Eduardo Rodriguez, director of NYU Langone’s Face Transplant Program. “He is the most highly motivated patient I have ever met,” Rodriguez…  read on >  read on >

Just one dose of Pfizer’s coronavirus vaccine might be enough to largely protect people from being infected with COVID-19, preliminary research shows. The vaccine became 90% effective 21 days after the first shot in a two-dose regimen, said British researchers who looked at data from Israel, where the vaccine has been rolled out to a large portion of the population. “A second dose of the Pfizer vaccine would normally be given 21 days or more after the first, to top up and lengthen the effect of the first dose,” explained lead researcher Paul Hunter, from the University of East Anglia’s Norwich Medical School. “But here in the U.K., the decision was made to delay the timing of the second injection until 12 weeks after the first,” Hunter said in a university news release. “The logic behind this is to protect more people sooner and so reduce the total number of severe infections, hospitalizations and deaths,” Hunter explained. “But this decision caused criticism from some quarters, due in part to a belief that a single injection may not give adequate immunity.” Hunter noted that an earlier study, which has not been peer-reviewed, reported that a single shot of the Pfizer vaccine might not provide sufficient protection. “But we saw a number of flaws in how they looked at the data, including the fact that they did…  read on >  read on >

Joe DiMeo’s life changed forever when he fell asleep at the wheel on U.S. Route 22 in New Jersey on July 14, 2018. The horrific crash left him with third-degree burns on 80% of his body and a grim prognosis. Now, more than two years later, DiMeo, 22, is the recipient of the world’s first successful double hand and face transplant, and on the road to recovery. The historic surgery, which took place on Aug. 12, 2020, at NYU Langone in New York City, involved more than 140 health care professionals. Over 23 hours, they successfully transplanted two hands, three dominant nerves to the hand, six blood vessels, 21 tendons and a full face, including forehead, eyebrows, both ears, nose, eyelids, lips, and underlying skull, cheek, nasal and chin bone segments. Face and hand transplants have been performed independently, but this double procedure had been attempted twice before and was unsuccessful both times. For this procedure, surgeons used computer-generated three-dimensional guides. They ensured that bones were properly aligned and implants were in position to anchor the grafted face and hands to DiMeo. Technology aside, a big part of DiMeo’s success owes to his can-do attitude, according to the head of his surgical team, Dr. Eduardo Rodriguez, director of NYU Langone’s Face Transplant Program. “He is the most highly motivated patient I have ever met,” Rodriguez…  read on >  read on >

Many young Americans are prescribed psychiatric drugs to treat medical conditions, but nearly one-third of them wind up misusing the medications, a new study finds. “Misuse of prescription substances is alarmingly high among U.S. youth and young adults,” said lead researcher Israel Agaku, a part-time lecturer in oral health policy and epidemiology at the Harvard School of Dental Medicine, in Boston. The study found that, overall, 35% of young people (aged 12 to 25) said they had taken a prescribed psychoactive drug in the past year, and 31% of those said they had misused that drug. While opioids were the most commonly prescribed drug, misuse of stimulants and tranquilizers was higher. Psychotropic drugs change a person’s mental state and can have intoxicating effects. “This study draws attention to the silent epidemic of prescription stimulant use among youth,” Agaku said. “With increasing popularity of performance-enhancing stimulants in schools, it is imperative for policymakers, school administrators, health care professionals and parents to become more aware of this emerging danger and take appropriate steps, similar to what has been done for the opioid epidemic.” Dr. Scott Krakower, an attending psychiatrist in child and adolescent psychiatry at Zucker Hillside Hospital in Glen Oaks, N.Y., said, “It is very alarming to see so many young people having access to controlled substances.” It is important for doctors to screen for illicit…  read on >  read on >

College football players suffer more concussions and head hits in practice than they do actually playing the game, a new study suggests. Across five seasons of football, 72% of concussions and 67% of head impacts incurred by players on six National Collegiate Athletic Association (NCAA) Division I teams happened during practice rather than on game day, researchers found. The incidence of concussion and head impacts also were disproportionately higher in the preseason than the regular season, said lead researcher Michael McCrea, director of the Brain Injury Research Program at the Medical College of Wisconsin in Milwaukee. “Our data suggest modifying preseason training activities and football practice throughout the season could lead to a substantial reduction in overall concussion incidence and head impact exposure,” McCrea said. The findings were published Feb. 1 in the journal JAMA Neurology. While these specific findings are new, experts and coaches have known for years that practice is at least as dangerous as actual play when it comes to head trauma, said Dr. Robert Cantu, medical director and director of clinical research at the Cantu Concussion Center at Emerson Hospital in Concord, Mass. That’s why the National Football League agreed in 2015 to dramatically reduce full-contact practices in its collective bargaining agreement with the NFL Players Association, said Cantu, who wrote an editorial accompanying the new study. The NFL now has…  read on >  read on >

It only takes a second. Experts are warning that unsecured televisions, bedroom dressers and other heavy furniture can crush, maim and even kill curious children, and the issue may only worsen during stay-at-home lockdowns. According to the U.S. Consumer Product Safety Commission (CPSC), between 2000 and 2019, 451 kids aged 17 years and younger died in tip-over accidents, the CPSC said. And an average 11,100 per year were treated in hospital emergency rooms for tip-over-related injuries from 2017 through 2019. “Tip-over injuries and deaths are among the most tragic we see,” Robert Adler, the agency’s acting chairman, said in a CPSC news release. “Parents and caregivers don’t suspect that the bookcase or dresser in their child’s room can be hazardous — it’s a truly hidden hazard. And these tip-overs happen so fast; it’s literally in the blink of an eye, often with a parent close by.” About eight in 10 tip-over deaths involved kids under age 6, and 75% of fatalities for children involved a TV, according to the new report. With millions of Americans preparing to watch the Super Bowl on Feb. 7, now is the time to anchor all TVs in your home, the agency said. This short CPSC video shows how quickly these tragedies can occur: A CPSC survey last year found that many parents and caregivers considered anchoring furniture and TVs…  read on >  read on >