A spike in the use of ADHD medications during the pandemic likely prompted drug shortages that continue to frustrate patients and doctors today, a new study shows. New prescriptions for stimulants that treat the condition jumped for young adults and women in particular after the pandemic first struck in March 2020, according to a study published Jan. 10 in the journal JAMA Psychiatry. Meanwhile, prescriptions also soared for non-stimulant ADHD treatments for adults of all ages, found researchers led by Grace Chai. She’s at the Office of Surveillance and Epidemiology at the U.S. Food and Drug Administration’s Center for Drug Evaluation and Research. Why the surge? The mental and emotional strain of the pandemic, coupled with an increased use of telemedicine that made it easier for patients to get help, were big contributors, experts said. Las Vegas psychiatrist Dr. Ann Childress told the Associated Press that more adults started coming to her for help after COVID-19 started sweeping across the country and lockdowns were put in place. Working from home made it clear to some people how easily they get distracted: Childress says she diagnosed a lot of parents, especially moms, who saw it in their children and recognized it in themselves. On top of that, social media has made people more aware of adult ADHD. “People are more open to talking about mental health issues now,”…  read on >  read on >

A bout of depression can trigger a bump in body weight among people struggling with obesity, a new study has found. People who had an increase in symptoms related to depression experienced an increase in their weight a month later, researchers report in the journal PLOS One.  “Overall, this suggests that individuals with overweight or obesity are more vulnerable to weight gain in response to feeling more depressed,” lead researcher Julia Mueller from the University of Cambridge’s Medical Research Council said in a university news release. The results support prior research pointing to a link between weight and mental health, with each potentially influencing the other. For the study, researchers examined data from more than 2,000 adults in the United Kingdom who were participating in a COVID-19 study. Participants completed monthly digital questionnaires on their mental well-being and body weight, using a mobile app. Questions in the study assessed each person’s symptoms of depression, anxiety and perceived stress. For every incremental increase in a person’s usual depression score, their weight increased by about a tenth of a pound one month later, results show. It might seem like a small weight gain, but researchers noted that if a person’s depression rose from five to 10 on the scale they used, it would relate to an average weight gain of a half-pound. “Although the weight gain was…  read on >  read on >

Weight gain has long been an unwanted side effect of medicines commonly used to treat psychiatric conditions such as bipolar disorder or schizophrenia.  Some patients may quit their meds to avoid piling on pounds. Or if they stick to their meds and weight gain continues, they face higher risks for diabetes and liver disease.  However, research in mice is pinpointing how this drug-linked weight gain happens in the first place — and how to stop it. The answer may lie in a hormone called leptin, explain researchers at the University of Texas Southwestern Medical Center in Dallas. According to the Cleveland Clinic, leptin is a hormone that’s emitted by fat cells and is involved in hunger and weight maintenance. Prior research has shown that patients who start taking common psychiatric meds such as olanzapine (used against bipolar disorder) and risperidone (used to treat schizophrenia) typically experience an uptick in their leptin levels before a surge in weight gain. The new study was conducted in mice. It might explain how a drug-induced rise in leptin is linked to added pounds.  “While it was historically viewed as a ‘passenger’ to obesity – meaning [leptin] levels go up as we gain weight – our data strongly suggest that it is a ‘driver’ for drug-induced obesity,” said study lead author Philipp Scherer. He’s professor of internal medicine and director…  read on >  read on >

Social media is abuzz with the possibility that newfangled weight loss drugs can also reduce cravings for alcohol, a new study says. Across a number of Reddit threads, users of weight-loss drugs like Ozempic reported that they felt less need to drink beer, wine and liquor. Threads bearing titles like “Did scientists accidentally invent an anti-addiction drug?” and “I don’t know if this is a side effect but … Mounjaro makes me drink less!!!!!” tout the weight-loss drugs’ potential to help folks quit drinking, researchers said. What’s more, a small study of social media participants with obesity found that they drank less and were less likely to binge if they were on a weight-loss drug. “These findings add to a growing literature that these medications may curb dangerous drinking habits,” said senior author Warren Bickel in a Virginia Tech news release. Bickel is a behavioral health research professor with the Fralin Biomedical Research Institute at Virginia Tech in Roanoke. For this study, Bickel and his team analyzed more than 68,000 Reddit posts sent between 2009 and 2023 that included terms linked to GLP-1 agonists like Wegovy, Ozempic, Mounjaro and Trulicity. GLP-1 agonists help manage blood sugar levels and reduce the desire to eat by mimicking the action of hormones that the body naturally releases after a meal, researchers said in background notes. The drugs were…  read on >  read on >