Health/Fitness « Weekly Gravy

Patients with a type of multiple sclerosis (MS) known as relapsing-remitting MS could have less fatigue if they got more active and were in better physical shape, according to new research. The study also found that a lower disability rate was also associated with less fatigue. “The findings are interesting and support previous studies very well,” said corresponding author Marko Luostarinen, a doctoral researcher at the University of Eastern Finland, in Kuopio. “Patients with MS should find a suitable form of exercise, taking into account their disability, which maintains their functional capacity and reduces fatigue.” In relapsing-remitting MS (RRMS), patients experience periods of new symptoms or relapses that are followed by quiet periods of remission that can last months or even years. Fatigue is a common MS symptom. The aim of the study was to investigate the connection between fatigue and disability in patients with RRMS. The study used several methods to gauge this, including measures of fatigue, disability and physical activity. Patients whose level of disability, as assessed by a measure called the expanded disability status scale (EDSS), was moderately low (0 to 2.5) had a higher level of fatigue than healthy participants with whom they were compared, the study found. At the same time, they had less fatigue than patients whose disability was higher (EDSS of 3 to 5.5). The researchers found a… read on > read on >

A large clinical trial weighing the medical merits of the obesity drug Wegovy has unearthed a significant positive side effect. Taking the medication cut the risk of serious heart problems by 20%, drug maker Novo Nordisk announced Tuesday. “People living with obesity have an increased risk of cardiovascular disease but, to date, there are no approved weight-management medications proven to deliver effective weight management while also reducing the risk of heart attack, stroke or cardiovascular death,” Martin Holst Lange, executive vice president for development at Novo Nordisk, said in a company news release. According to Dr. Howard Weintraub, clinical director of the Center for the Prevention of Cardiovascular Disease at NYU Langone Heart, in New York City, “There is now a drug that is well-tolerated and safe from a cardiovascular perspective, that also lowers body weight in an effective manner. On top of all of this, there is significant reduction in the cumulative outcome of nonfatal MI [heart attacks], cardiac death and stroke.” “This is a very important study,” he added, “as no other weight loss medication has been shown to reduce cardiovascular events. It is likely that the beneficial impacts of this drug go above and beyond just weight loss. We were part of this important trial, and I think we all agree that this was a very important study.” However, Novo Nordisk did… read on > read on >

A new brain-zapping technology may help ease the symptoms of attention deficit hyperactivity disorder (ADHD) in children without some of the side effects stimulant medications can cause, a small, preliminary study suggests. Marked by trouble concentrating, sitting still and/or controlling impulsive behaviors, ADHD affects about 5.3 million children, according to Children and Adults with Attention-Deficit/Hyperactivity Disorder (CHADD). The new technology, called transcranial random noise stimulation (tRNS), involves placing two electrodes on the brain where they emit a mild, painless electrical current. The study was funded by Tech Innosphere Engineering Ltd., the device manufacturer. “A novel form of noninvasive, safe and painless brain stimulation led to a significant effect on ADHD symptoms reduction that persisted three weeks after the end of the intervention,” said study author Roi Cohen Kadosh, head of the School of Psychology at the University of Surrey in England. Still, the new technology is not ready for prime time yet, he added. “The results are promising, but we need to extend it to a larger population of patients, which we are planning to start this year,” Cohen Kadosh said. Exactly how the technology works to reduce ADHD symptoms isn’t fully understood yet, added study author Mor Nahum, head of the Computerized Neurotherapy Lab at Hebrew University in Jerusalem. “In ADHD kids, we know that some of the frontal brain areas may be less… read on > read on >

In the midst of a childhood obesity epidemic, a new study is pointing to a way to help school kids maintain a healthier weight: clean, accessible drinking water. The decidedly low-tech solution emerged in a study of 18 California elementary schools that serve largely low-income minority families. Researchers found that when they kicked off a “Water First” program — which included putting tap water stations in the schools — it made a difference in kids’ weight gain. At the nine schools where the program launched, the percentage of kids who fell into the overweight category held fairly steady over 15 months. In contrast, that figure rose by almost 4 percentage points at schools without the water program. Experts said the impact was striking, given that encouraging kids to drink water is just one simple step. “I think the fact that they were able to find this difference is pretty remarkable,” said Marlene Schwartz, director of the Rudd Center for Food Policy and Obesity at the University of Connecticut. It’s generally tough to move the needle when it comes to kids’ weight, because it is influenced by so many factors, noted Schwartz, who was not involved in the study. Dr. Anisha Patel, who led the research, pointed to the relative simplicity of the tactic — which could have multiple benefits, including cavity prevention and keeping kids… read on > read on >

Whether you got a tattoo on a whim or after much thought, that ink on your body is fairly permanent. Tattoo removal is possible, but it comes with risks, according to the U.S. Food and Drug Administration, which regulates tattoo ink and pigment, as well as the laser devices used to remove them. State and local authorities typically oversee tattooing practices. The FDA has cleared several types of lasers for tattoo lightening or removal. They are to be used by or under the supervision of a health care professional. The process requires using the correct type of laser, understanding how tissue will react and knowing how to treat the area after the procedure. One challenge with removal is that tattoos are more than skin deep. The needle injects ink into the skin, penetrating the epidermis, or outer layer. And it also deposits a drop of ink into the dermis, the layer underneath. The cells of the dermis are more stable than those of the epidermis, which, the FDA said, means the ink will mostly stay in place for a person’s lifetime. Lasering is the most common method for removing or lightening tattoos, according to the FDA. Laser light energy shatters the tattoo ink into small particles, and the immune system clears these particles over time. Different types of lasers may be used depending on the… read on > read on >

A Louisiana woman is suing the makers of two type 2 diabetes drugs used off-label for obesity, saying they failed to adequately warn about the risk of severe stomach problems. The lawsuit seeks “very significant” but unspecified compensation from the makers of both Ozempic and Mounjaro, said attorney Paul Pennock of the Orlando, Fla.-based firm Morgan & Morgan. Pennock filed the lawsuit Wednesday on behalf of Jaclyn Bjorklund, 44, NBC News reported. The lawsuit against Novo Nordisk and Eli Lilly claims Bjorklund was “severely injured” after taking the two diabetes drugs, which are part of a new class of medication called GLP-1 agonists. Pennock said she is suffering “persistent” vomiting and severe gastroparesis, also known as stomach paralysis. Gastroparesis slows or stops food from moving out of the stomach and into the small intestines. It can be caused by underlying medical issues, including diabetes, according to the American College of Gastroenterology. Infections and some medication can also cause it. The GLP-1 agonists slow food’s movement and have been found to cause some GI issues in clinical trials. Those are listed as side effects on the drug labels. Both Ozempic and Mounjaro have the phrase “delays gastric emptying” on their prescribing information, though they don’t specifically use the word “gastroparesis,” NBC News reported. A U.S. Food and Drug Administration spokeswoman said it was unclear whether the… read on > read on >

Yoga is known for its benefits to both the mind and body. And a gentle form of yoga may be an ideal early intervention technique for older women at risk of Alzheimer’s disease, new research suggests. In a small study involving kundalini yoga, participants reported that its stress-relieving effects translated to more efficient memory. “Women tend to practice yoga more readily than men. And I’ve done other studies previously in people, older adults with mild cognitive [mental] impairment and in caregivers with similar interventions,” said Dr. Helen Lavretsky, the lead psychiatrist on the study. “We are focusing now on women who are not as impaired as in my previous study, but still at risk for cognitive decline. And the idea is to get to the level where doing yoga would prevent future cognitive decline and development of Alzheimer’s disease,” said Lavretsky, a professor-in-residence at the University of California, Los Angeles. Kundalini yoga involves chanting, singing, breathing exercises, meditation and gentle poses with the aim of increasing awareness in the mind and body. Previous scientific research has found that yoga can help regulate blood pressure and increase cardiorespiratory fitness, as well as benefit the hippocampus, or the region in the brain that is associated with memory. In this study, scientists examined the effects of kundalini yoga versus memory enhancement training (MET) on the hippocampus in 22… read on > read on >

Golfing may be a great way to get outdoors and enjoy the pleasures of a classic summer pastime. But a new study warns that walking the greens for hours on end without adequate sun protection may notably increase the risk for skin cancer. Researchers in Australia found that more than one-quarter of golfers in that country have been diagnosed with skin cancer at some point, making Aussie players 2.4 times more likely to get the disease than their non-golfing peers. “Our previous research, and that of others worldwide, has demonstrated the positive impact of golf on people’s health, including physical, mental and cognitive well-being,” said study lead author Brad Stenner. At the same time, “Australia is well known for its high skin cancer rates, and frequency and intensity of sun exposure,” said Stenner, a lecturer in health and human performance at the University of South Australia in Adelaide. However, “the cumulative effects of sun exposure do increase the risks of skin cancer, regardless of where you live,” he added. Knowing this, golfers should more actively strive to protect themselves, Stenner and other experts said. In the new research, just 7% of those in the general public reported ever having a skin cancer diagnosis versus 27% of the golfers. This suggests golfers face a nearly 250% greater risk of developing skin cancer than non-players, the study… read on > read on >

More girls started puberty before age 8 during the COVID-19 pandemic, a phenomenon called precocious puberty, researchers say. The reasons include potential risk factors such as increased screen time and less exercise, according to a new study, published online Aug. 3 in the Journal of the Endocrine Society. In precocious puberty, children’s bodies begin changing into adult bodies too soon. These changes normally begin between age 8 and 14. The number of girls referred to pediatric endocrinologists for precocious puberty rose substantially over the past two years, researchers found. COVID-19 has also been linked to endocrine diseases, including obesity, which can contribute to early puberty in girls. “Our study confirms the rise in precocious puberty diagnoses during COVID-19 and identifies contributing factors such as poor eating and exercise habits, too much screen time and impaired sleep,” said study author Dr. Mohamad Maghnie, of the University of Genoa and the Giannina Gaslini Institute in Italy. “We found an increase in weight gain among girls diagnosed with precocious puberty during the pandemic, and rapid increase in body weight is associated with advanced pubertal development,” he said in a journal news release. The researchers studied data on rates of precocious puberty from before and after the pandemic in 133 girls in Italy. They also considered the possible relationship between COVID-19 and pandemic-related lifestyle changes. They found 72 cases… read on > read on >

While demand for prescription stimulants is surging, a shortage of the drugs persists, so federal officials have stepped in and asked drug companies to ramp up production of the medications. Officials from both the U.S. Food and Drug Administration and the U.S. Drug Enforcement Administration (DEA) made the joint request. “The FDA and DEA do not manufacture drugs and cannot require a pharmaceutical company to make a drug, make more of a drug or change the distribution of a drug,” FDA Commissioner Dr. Robert Califf and Drug Enforcement Administration leader Anne Milgram wrote in a letter issued Tuesday. “That said, we are working closely with numerous manufacturers, agencies and others in the supply chain to understand, prevent and reduce the impact of these shortages.” The agencies are also asking prescribers to carefully monitor their prescribing practices. “The lack of availability of certain medications in recent months has been understandably frustrating for patients and their families,” Califf and Milgram wrote in their letter. Reasons for the shortage include manufacturing delays by one drugmaker last fall. Meanwhile, demand for prescription stimulants for adults surged during the pandemic, according to a U.S. Centers for Disease Control and Prevention report. The FDA first announced a shortage of Adderall last October; that medication is commonly used for those with attention deficit hyperactivity disorder (ADHD). The DEA limits the amount of… read on > read on >