If you belong to one of the 46 million American households with a cat, you already know how stressful a trip to the vet can be for your feline — and you. Rescue might be on the way: The U.S. Food and Drug Administration on Friday approved a new medicine to help calm cat anxiety. The pill is called Bonqat, and it’s designed “for the alleviation of acute anxiety and fear associated with transportation and veterinary visits in cats,” the FDA said in a news release announcing the approval. “The drug is administered orally approximately 1.5 hours before the start of the transportation or veterinary visit and can be given on two consecutive days,” the agency added. Bonqat contains pregabalin, a drug that calms overactive nerves. Bonqat is the first FDA-approved drug to contain pregabalin. According to information from the VCA Animal Hospitals, some cats can develop severe anxiety and motion sickness being transported to the vet’s office (or anywhere). Symptoms can range from lots of meowing, lip smacking and drooling, to stress-induced motion sickness that can trigger urination and defecation in anxious cats. Medications given before a vet trip might help. The FDA approval of Bonqat was based on real-world trials conducted by the drug’s Finnish maker, Orion Corp. People whose cats had a history of fear and anxiety during veterinary visits were asked…  read on >  read on >

Nearly half of Americans have never heard of health-threatening PFAS “forever chemicals,” a new survey has found. PFAS (perfluoroalkyl and polyfluoroalkyl substances) are a category of thousands of manufactured chemicals that have become an emerging concern to environmental and human health, researchers from Texas A&M University said. Nonetheless, 45% of survey participants had never heard of PFAS and did not know what they are, according to findings published Nov. 16 in the journal PLOS One. “This is the first survey of its kind, and what we found is that the vast majority of people do not have a clear understanding of PFAS,” said lead researcher Allen Berthold, interim director of the university’s Texas Water Resources Institute (TWRI). PFAS are called “forever chemicals” because they combine carbon and fluorine molecules, one of the strongest chemical bonds possible, researchers explained. This makes PFAS removal and breakdown very difficult. PFAS compounds have been used in consumer products since the 1940s, including fire extinguishing foam, nonstick cookware and food wrappers, researchers said. PFAS also has been detected in food and water supplies. The U.S. Geological Survey estimates that at least 45% of the nation’s tap water contains one or more PFAS chemicals, and in March the Environmental Protection Agency proposed a national standard for PFAS in drinking water. “Research has come out in the last year showing that many…  read on >  read on >

Biologic drugs to treat asthma have been around for two decades, but a surprising number of family doctors still aren’t prescribing them to kids and adults. A new survey found that more than two in five primary care docs (42%) are unfamiliar with asthma biologics, according to findings presented at this month’s American College of Allergy, Asthma and Immunology annual meeting in Anaheim, Calif. The doctors didn’t know the criteria for prescribing the drugs — including essential lab work — and often waited until a patient had experienced two or more asthma attacks in a year before referring them to an asthma specialist, the survey found. “We know that many people who suffer from asthma are regularly seen by PCPs, and we wanted to know if PCPs were familiar with biologics to treat asthma,” said lead researcher Dr. Bijalben Patel, a resident at the University of South Florida (USF).  “We also wanted to explore at what point PCPs were referring asthma patients with uncontrolled symptoms to asthma specialists, and whether they were aware of eligibility requirements for a patient to start biologic treatment,” Patel added in a meeting news release. The researchers surveyed 85 primary care physicians via e-mail, including internists, family medicine specialists and pediatricians. They found that 82% do not get the labs needed to prescribe biologics, including 90% who do not test…  read on >  read on >

The song says ‘tis the season to be jolly, but many Americans find it to be more the season of stress and worry, a new survey reports. The strain of inflation and world affairs this year are adding to the other holiday-time stressors to create a toxic mental health cocktail, according to findings from Ohio State University’s Wexner Medical Center and College of Medicine. Survey results show that: 81% of Americans are stressing out over national issues and world affairs 75% are stressed about rising prices and holiday spending 53% are stressed from increasing cases of flu, COVID and other respiratory illnesses 44% are stressed from memories of last year’s holiday travel meltdown These findings run counter to the notion that holidays are supposed to be a time for families and friends to connect, recharge and enter the new year with a fresh outlook, said researcher Nicole Hollingshead, a psychologist in the Department of Psychiatry and Behavioral Health at the Wexner Medical Center. “The holidays kind of bring on this feeling of sadness and struggle when we really want it to be more of a joyous time,” Hollingshead said in a university news release. “I encourage people to reflect on what the holidays meant for you growing up. And most of the time I don’t hear people reflect on, ‘I loved having all the presents,…  read on >  read on >

It’s been around for a century, and electroconvulsive therapy — formerly known as electroshock therapy — has helped countless people with psychiatric conditions feel better. But even the physicians who’ve used it have had little clue as to how it works. Now, a team the University of California, San Diego (UCSD) believe they’ve unraveled that mystery. “We’re solving a puzzle that’s stumped scientists and doctors since electroconvulsive therapy [ECT] was first developed nearly a century ago,” said study first author Sydney Smith, a PhD candidate in the Voytek Lab at UCSD. “On top of that, we’re also helping to demystify one of the most effective, yet stigmatized, treatments for severe depression.”  After decades of harrowing depictions in TV shows and movies, the treatment probably does need to improve its image. “A lot of people are surprised to learn that we still use electroconvulsive therapy, but the modern procedure uses highly controlled dosages of electricity and is done under anesthesia,” Smith said in a university news release. “It really doesn’t look like what you see in movies or television.”  And ECT has a remarkable success rate: It’s effective in easing serious mental health issues such as bipolar disorder, schizophrenia and severe depression up to 80% of the time, the team said. There are some downsides: ECT requires multiple outpatient visits, and post-treatment side effects can include…  read on >  read on >

Middle-aged folks with lots of belly fat surrounding their internal organs appear to be at higher risk for Alzheimer’s disease later in life, a new study suggests. This hidden abdominal fat — known as visceral fat — is related to changes in the brain up to 15 years before the earliest symptoms of Alzheimer’s manifest, according to findings to be presented at next week’s annual meeting of the Radiological Society of North America. Such research is considered preliminary until published in a peer-reviewed journal. For this study, researchers compared brain scans of 54 people between the ages of 40 and 60 with their levels of belly fat, BMI, obesity and insulin resistance. The scans looked for the size of people’s brains, as well as levels of amyloid beta and tau proteins that have been previously linked to Alzheimer’s. “Even though there have been other studies linking BMI with brain atrophy or even a higher dementia risk, no prior study has linked a specific type of fat to the actual Alzheimer’s disease protein in cognitively normal people,” said researcher Dr. Mahsa Dolatshahi, a postdoctoral research fellow with the Mallinckrodt Institute of Radiology at Washington University School of Medicine in St. Louis. “Similar studies have not investigated the differential role of visceral and subcutaneous fat, especially in terms of Alzheimer’s amyloid pathology, as early as midlife,” Dolatshahi…  read on >  read on >

A young woman working at a Massachusetts cannabis-processing facility who developed new-onset asthma and later died of a fatal asthma attack is the first such fatality in the burgeoning industry, a new report finds. Researchers believe large amounts of allergen-laden dust created at these facilities could pose real respiratory dangers to workers. When it comes to asthma and the danger to employees, “it is important to recognize that work in cannabis production is potentially causative,” said a team led by Dr. Virginia Weaver, of the U.S. Department of Labor. In its case report, Weaver’s team said the 27-year-old female employee began working at a Massachusetts cannabis cultivation and processing facility in late May of 2021.   She had no history of asthma but, according to her mother, “she developed work-related runny nose, cough and shortness of breath after 3-4 months of employment,” the report found. The woman first worked in the area where the cannabis was ground, but by Oct. 1 she’d moved to “flower production,” grinding cannabis plant flowers and preparing cannabis cigarettes. Dust “visibly escaped” into the air, even though a (non-HEPA) shop vacuum was used to collect dust from the grinder. The woman did wear an N95 mask and protective gloves while working, but as her symptoms worsened her workstation was moved to outside the grinding room.  However, on Nov. 9 she had…  read on >  read on >

Have a hard time looking others in the eye? You aren’t alone, Canadian researchers report. Eye-to-eye contact rarely occurs when two people are talking, they found. “We discovered that participants spent only about 12% of conversation time in interactive looking, meaning that they gazed at each other’s faces simultaneously for just 12% of the interaction duration,” said lead researcher Florence Mayrand, a doctoral student with the McGill University department of psychology in Montreal. “Even more surprisingly, within those interactions, participants engaged in mutual eye-to-eye contact only 3.5% of the time,” Mayrand added in a university news release. But when someone does look you in the eye, take note — the gesture communicates nonverbal information that’s vital for future interaction, the researchers noted. For the study, the research team paired up participants and presented them with an imaginary survival scenario. In this scenario, they had to rank a list of items in order of their usefulness for survival, all while wearing mobile eye-tracking glasses. Researchers analyzed how often participants looked at each others’ eyes and mouths, as well as whether they followed the other person’s gaze. During the interactions, participants spent more time looking away than looking at their partner’s faces, researchers found. When they did look at each others’ faces, they looked equally often at the mouth and the eyes, and spent little time in…  read on >  read on >

A pregnant woman’s mental health might have profound effects on the mind of her unborn child, a new evidence review warns. Children appear to be at higher risk for mental health and behavior issues if their moms were highly stressed, anxious or depressed during pregnancy, researchers report. In particular, children were more likely to have ADHD symptoms or exhibit aggressive or hostile behavior if their moms reported more anxiety, depression or stress while pregnant. “Our research suggests that psychological distress during the pregnancy period has a small but persistent effect on children’s risk for aggressive, disinhibited and impulsive behaviors,” said researcher Irene Tung, an assistant professor of psychology at California State University, Dominguez Hills. For the review, Tung and her colleagues pooled and analyzed data from 55 studies involving more than 45,000 participants. All the studies measured women’s psychological distress during pregnancy, and then later measured their children’s “externalizing behaviors” — mental health symptoms directed toward others. The researchers also included only research where the mothers’ distress was measured both during and after pregnancy, to control for the potential effects of postpartum mental health problems on developing newborns. They found that even after controlling for mom’s postnatal distress, psychological symptoms during pregnancy independently raise children’s risk of mental health problems. The effect held true for both boys and girls. It was strongest in early childhood…  read on >  read on >