Evaluating a person’s psychological stress can be a good way to gauge their risk of heart and blood vessel disease, new research suggests. And a brief questionnaire could help with the assessment, the study findings showed. “Our study is part of the accumulating evidence that psychological distress is a really important factor in a cardiovascular diagnosis, such as the other health behaviors and risk factors, like physical activity and cholesterol levels, that clinicians monitor,” said co-author Emily Gathright. She is an assistant professor of psychiatry and human behavior at Brown University’s Warren Alpert Medical School, in Providence, R.I. For the study, the team looked at research published within the past five years that included adults without a psychiatric diagnosis who were screened for depression, anxiety, post-traumatic stress disorder, stress or general mental health symptoms, and followed for more than six months. About 58% were women. In all, Gathright and her colleagues analyzed findings from 28 studies that included more than 658,000 patients. Those reporting high levels of psychological distress had a 28% higher risk of heart disease, the investigators found. According to study co-author Carly Goldstein, an assistant professor of psychiatry and human behavior, a brief mental health questionnaire can give clinicians a better idea not only of a patient’s mental health risks, but also their associated risk for heart disease. Based on the results…  read on >  read on >

Folks taking dietary supplements intended to help their heart health are just wasting their money, a new clinical trial suggests. Six supplements widely promoted as heart-healthy — fish oil, cinnamon, garlic, turmeric, plant sterols and red yeast rice — didn’t do a thing to lower “bad” low-density lipoprotein (LDL) cholesterol or improve heart health, researchers found. “Compared to placebo, none of the supplements had a significant decrease in LDL cholesterol,” said lead researcher Dr. Luke Laffin, co-director of the Cleveland Clinic’s Center for Blood Pressure Disorders. In fact, two of the supplements made matters worse, Laffin said during a presentation on the findings Sunday at the American Heart Association’s annual meeting, in Chicago. The study findings were published Nov. 6 in the Journal of the American College of Cardiology. The garlic supplement actually increased LDL cholesterol by nearly 8%, while plant sterols decreased “good” high-density lipoprotein (HDL) cholesterol levels by more than 7%, the results showed. The clinical trial also demonstrated that statins are incredibly effective in lowering cholesterol. A low dose of cholesterol-lowering rosuvastatin (Crestor) prompted, on average, a nearly 38% decrease in bad LDL cholesterol, Laffin said. “Every participant randomized to rosuvastatin had at least an 18.2% reduction in LDL cholesterol, with half receiving over 40% reduction in LDL cholesterol,” Laffin said. “Whereas with all the supplements and placebo, you might as well…  read on >  read on >

As the daylight hours shrink, people’s moods can wind up in the tank. Rest assured, you’re not alone. It’s the SAD season for those affected by seasonal affective disorder. That’s the depression, fatigue and withdrawal that shorter days and longer nights often bring. “The seasonal mood change can come in different shapes and forms,” said Dr. Dorothy Sit, associate professor of psychiatry and behavioral sciences at Northwestern University Feinberg School of Medicine, in Chicago. “It can be a clinical diagnosis of depression, which we call SAD, but some people experience a milder form,” Sit said. “The clinical diagnosis means it is quite intense; it affects people all day for many weeks and can impact their functioning. In milder cases, people can feel a bit blah, but can push through. Still, functioning will feel a bit harder.” Besides feeling sluggish, people may be hungrier, crave carbohydrates, eat more and gain weight. They may also feel less motivated and find less enjoyment in activities. “This is a form of depression that cycles naturally; it starts every fall and winter and remits every spring and summer,” Sit said in a Northwestern Medicine news release. A major remedy for SAD is starting the day with bright light therapy. Sit recommends a unit that produces 10,000 LUX of white light to be used in the 30 minutes after waking up.…  read on >  read on >

Deaths caused by alcohol skyrocketed in the United States between 2019 and 2020 as the COVID-19 pandemic took hold, according to a just-published government report. The alcohol-induced death rate jumped 26% during that period, claiming more than 49,000 lives, the U.S. Centers for Disease Control and Prevention reported Friday. That’s about 13 deaths for every 100,000 people. In 2019, the alcohol-induced death rate stood at 10.4 deaths per 100,000, CNN reported. Americans drank more during the COVID pandemic than before, and a health expert said it’s possible this is just the beginning of a disturbing trend. “We know that in large-scale traumatic events to the population – like 9/11 or Hurricane Katrina – people historically start drinking more. The pandemic has been, as we all know, a major stressor to our lives,” said George Koob, director of the U.S. National Institute on Alcohol Abuse and Alcoholism. “What we’ve been picking up with numerous small studies is that about 25% of the population increased their drinking and these individuals were people who were drinking to cope with stress,” he said. “And many people who drink to cope with stress inevitably go on to have an alcohol use disorder.” More than half of the 2020 deaths caused by alcohol were due to alcoholic liver disease, CNN reported. Other causes included mental health and behavioral disorders due to…  read on >  read on >

The U.S. Food and Drug Administration has proposed limiting the amount of nicotine in cigarettes to minimally addictive levels, but there’s been concern that the drop in nicotine could exacerbate anxieties in smokers who might already battle mood issues. However, a new study shows that while cigarettes with nicotine at 5% of the normal dose can help anxious or depressed smokers quit, they do so without adding to mood or anxiety problems that led them to smoke in the first place. “There do not appear to be any concerning, unintended consequences of having to switch to very low nicotine cigarettes,” said lead researcher Jonathan Foulds, a professor of public health sciences and psychiatry at Penn State University School of Medicine. “On the contrary, it appears that the result is that smokers feel less addicted to their cigarettes and more able to quit smoking when offered relatively brief assistance with follow-up appointments plus nicotine replacement therapy,” he said. Smokers with mood and anxiety disorders showed no signs of “over-smoking” the very low-nicotine cigarettes, nor was there any sign that switching to them made their mental health worse, Foulds said. The U.S. Food and Drug Administration has proposed limiting the amount of nicotine in cigarettes to minimally addictive levels. Doing so could not only lessen addiction, but also reduce exposure to toxic substances and increase the odds…  read on >  read on >

A single psychedelic trip with psilocybin — the mind-altering component of magic mushrooms — appears to lift the fog of major depression in some hard-to-treat patients, a new clinical trial reports. A 25-milligram dose of a synthetic psilocybin compound called COMP360 caused a “rapid and durable response” in more than a third of patients suffering from treatment-resistant depression, said Dr. Steve Levine, senior vice president of patient access for the London-based pharmaceutical company COMPASS Pathways. It focuses on psilocybin research and created the COMP360 synthetic compound and funded the clinical trial. The results occurred in a phase 2 trial aimed at finding the most effective dose of COMP360, according to a report published Nov. 3 in the New England Journal of Medicine. However, there was one caveat: While side effects were minimal, four patients (out of 79) who took the highest dose either reported having suicidal thoughts or intentionally harming themselves in the weeks that followed. The psilocybin compound will now proceed to a full-fledged clinical trial that promises to be the largest ever conducted for a psychedelic compound, Levine said. The trial testing its effectiveness is expected to include more than 900 people in 14 countries, including the United States, Levine said. It’s expected to conclude in mid-2025. These early findings show that psilocybin could well provide an alternative to standard treatments for major…  read on >  read on >

When it comes to love, first impressions matter. But what exactly fuels the flames of romance? It turns out that compatibility and popularity are two of the key factors shaping who people pursue as potential partners, a new speed-dating study suggests. “Although we expected that compatibility would be an important factor, we were amazed to find that compatibility was just as strong of a predictor of romantic pursuit as popularity was,” said study author Alexander Baxter, a PhD candidate in the psychology department at the University of California, Davis. For the study, researchers analyzed romantic first impressions among more than 550 speed-daters, including some men who date men, to rate their romantic interest in potential partners. There were more than 6,600 speed-dates in total during the experiment. The research team looked at three factors that affect how romantic first impressions form: selectivity, popularity and compatibility. “If Daniel liked Rose because he tended to like everyone, this would be selectivity,” Baxter explained. “If Daniel liked Rose because everyone liked her, this would be popularity, and if Daniel uniquely liked Rose above and beyond his own flirty disposition and her general popularity, this would be compatibility.” After the speed-dating events, the researchers asked folks if they dated anyone they met and how their feelings changed over the next two to three months. They used a statistical model…  read on >  read on >

A virus-linked cancer killing California sea lions is sounding a chilling alarm for mankind. Exposure to environmental toxins significantly boosts risk for the herpes-like cancer, which was discovered in sea lions in 1979. Since then, between 18% and 23% of adult sea lions admitted to a California animal rescue-and-research center have died of the disease. That’s the highest rate for a single type of cancer in any mammal, including humans, the researchers said. “The decades of research looking into this deadly disease clearly shows the ocean environment we all share is in trouble, and that we need to find solutions to protect our collective health,” said study co-author Pádraig Duignan, chief pathologist at The Marine Mammal Center in Sausalito, Calif. The study — based on more than 20 years of research and examination of nearly 400 California sea lions — was recently published in the journal Frontiers in Marine Science. The researchers said more must be done to stop ecosystem pollution in order to prevent virus-caused cancer in both wildlife and humans. The study found that the blubber of California sea lions has among the highest levels of some organic pollutants found in any marine mammal. “Even though some of the pollutants we’re finding in the blubber have been out of use for years, these cancer-causing elements remain in the environment for a very long…  read on >  read on >

A virus-linked cancer killing California sea lions is sounding a chilling alarm for mankind. Exposure to environmental toxins significantly boosts risk for the herpes-like cancer, which was discovered in sea lions in 1979. Since then, between 18% and 23% of adult sea lions admitted to a California animal rescue-and-research center have died of the disease. That’s the highest rate for a single type of cancer in any mammal, including humans, the researchers said. “The decades of research looking into this deadly disease clearly shows the ocean environment we all share is in trouble, and that we need to find solutions to protect our collective health,” said study co-author Pádraig Duignan, chief pathologist at The Marine Mammal Center in Sausalito, Calif. The study — based on more than 20 years of research and examination of nearly 400 California sea lions — was recently published in the journal Frontiers in Marine Science. The researchers said more must be done to stop ecosystem pollution in order to prevent virus-caused cancer in both wildlife and humans. The study found that the blubber of California sea lions has among the highest levels of some organic pollutants found in any marine mammal. “Even though some of the pollutants we’re finding in the blubber have been out of use for years, these cancer-causing elements remain in the environment for a very long…  read on >  read on >

A virus-linked cancer killing California sea lions is sounding a chilling alarm for mankind. Exposure to environmental toxins significantly boosts risk for the herpes-like cancer, which was discovered in sea lions in 1979. Since then, between 18% and 23% of adult sea lions admitted to a California animal rescue-and-research center have died of the disease. That’s the highest rate for a single type of cancer in any mammal, including humans, the researchers said. “The decades of research looking into this deadly disease clearly shows the ocean environment we all share is in trouble, and that we need to find solutions to protect our collective health,” said study co-author Pádraig Duignan, chief pathologist at The Marine Mammal Center in Sausalito, Calif. The study — based on more than 20 years of research and examination of nearly 400 California sea lions — was recently published in the journal Frontiers in Marine Science. The researchers said more must be done to stop ecosystem pollution in order to prevent virus-caused cancer in both wildlife and humans. The study found that the blubber of California sea lions has among the highest levels of some organic pollutants found in any marine mammal. “Even though some of the pollutants we’re finding in the blubber have been out of use for years, these cancer-causing elements remain in the environment for a very long…  read on >  read on >