The “love hormone” oxytocin might not play the critical role in forming social bonds that scientists have long believed, a new animal study suggests. Prairie voles bred without receptors for oxytocin display the same monogamous mating, attachment and parenting behaviors as regular voles, according to researchers. “While oxytocin has been considered ‘Love Potion No. 9,’ it seems that potions 1 through 8 might be sufficient,” said co-senior researcher Dr. Devanand Manoli, a psychiatrist with the University of California, San Francisco’s Weill Institute for Neurosciences. “This study tells us that oxytocin is likely just one part of a much more complex genetic program.” Prairie voles are one of the few mammals known to form lifelong monogamous relationships, so they are a natural fit for researchers looking into the biology of social bonding. Studies performed in the 1990s showed that oxytocin-blocking drugs left voles unable to pair-bond, researchers said in background notes. As a result, oxytocin gained its reputation as a love hormone. To dig further into that relationship, researchers used gene-editing tools to create prairie voles that lacked functional oxytocin receptors. They then tested the altered voles’ ability to form enduring relationships with other voles. The researchers were surprised to find that the mutant voles paired up as readily as normal voles. “The patterns were indistinguishable,” Manoli said in a university news release. “The major behavioral… read on > read on >

















