New research suggests that switching from smoking to vaping won’t prevent some dangerous changes to a person’s genome. A new study conducted in young adults shows similar cancer-linked gene changes in both vapers and smokers. “These findings have significant implications for public health and tobacco regulation that aim to keep vaping products away from young people, who are a particularly vulnerable population,” said study lead author Stella Tommasi. She’s an associate professor of research population and public health sciences at the University of Southern California (USC), Los Angeles. At issue is a process called DNA “methylation,” essentially an on/off switch for genes that tells DNA if it should operate. The new study looked at the genetics of 30 young adults averaging 23.5 years of age. Some were exclusive e-cigarette users, vaping at least three times per week for at least six months; some were exclusive smokers, smoking at least three times per week for at least a year; and some neither vaped nor smoked. Tommasi’s group used a high-tech gene sequencing technique to look at the genomes of cells taken from each participant in cheek swabs. They found 831 “differentially methylated regions” (DMRs) in the genomes of vapers and 2,863 in smokers. DMRs are genetic areas that may be more or less methylated (switched on/off) in one person versus another. Overall, there was a 46% overlap… read on > read on >

















