
Infection with the COVID-19 virus triggers the production of an immune system protein that’s long been associated with fatigue, muscle ache and depression. Trouble is, for folks suffering from Long COVID this protein overproduction does not stop, researchers at the University of Cambridge report. “We have found a potential mechanism underlying Long COVID which could represent a biomarker — that is, a tell-tale signature of the condition. We hope that this could help to pave the way to develop therapies and give some patients a firm diagnosis,” said study co-author Dr. Benjamin Krishna. There was another silver lining from the research: Vaccination against SARS-Cov-2, the virus that causes COVID-19, appears to lower production of the culprit protein, called interferon gamma (IFN-γ). “If SARS-CoV-2 continues to persist in people with Long COVID, triggering an IFN-γ response, then vaccination may be helping to clear this,” said Krishna, who works at the Cambridge Institute of Therapeutic Immunology & Infectious Disease. According to the latest data from the U.S. Centers for Disease Control and Prevention, almost 7% of Americans say they have experienced Long COVID. Most cite persistent fatigue as the major symptom, but Long COVID can also bring brain fog, chronic cough and other issues. The exact causes of the illness have remained unclear. In the latest study, Krishna’s team tracked outcomes for 111 COVID patients admitted to… read on > read on >