Treating men with low-risk prostate cancer with just one high dose of radiation may be safe and effective, British researchers report. Therapy for prostate cancer typically involves low-dose radiation given over several days or weeks. Conversely, high-dose radiation is given once through a set of tiny tubes inserted directly into the tumor. “For low-risk patients, a single dose of high-dose radiation is sufficient, but for medium- and high-risk patients, a single dose of 19 Gy isn’t enough. They will likely need a bigger dose or going back to multiple doses,” said lead researcher Hannah Tharmalingam. She’s a clinical research fellow at the Mount Vernon Cancer Centre in Northwood, England. According to Tharmalingam, high-dose radiation could be more convenient for low-risk patients, and less time-consuming and costly for the medical system. But one radiation oncologist fears that the side effects make it potentially dangerous. For the study, Tharmalingam and her colleagues treated 441 prostate cancer patients between 2013 and 2018. The cancers were classified as low-, medium- or high-risk. All of the men were treated with one high dose of 19 Gy of radiation, which is equivalent to the total amount of radiation given over several days with current treatments, Tharmalingam said. In addition, 166 men were also given hormone therapy. None of the men, however, had surgery or chemotherapy. For comparison, men with prostate cancer… read on >







