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Acne can be terribly embarrassing for a teenager, but a new study has found that adults’ blemishes might have even greater consequences for their social and professional reputation. People are less likely to want to be friends, have close contact or post a pic on social media with a person who has severe acne, researchers found. “Our findings show that stigmatizing attitudes about acne can impair quality of life, potentially by affecting personal relationships and employment opportunities,” said researcher Dr. John Barbieri, a dermatologist at Brigham and Women’s Hospital in Boston. “Acne is often wrongly perceived as merely a cosmetic issue,” Barbieri added. “It’s important that people with this medical problem get access to treatment, just like any other condition.” Acne occurs in a person’s hair follicles and oil glands, according to Johns Hopkins. Normally, oil from the glands travels up the hair follicles to the skin, keeping the skin moist. But if skin cells plug the follicles and block the oil, bacteria growing inside the follicles can cause pimples and cysts. For this study, Barbieri and his colleagues obtained stock photos of four adults, including men and women with either light or dark skin tone. The researchers digitally altered the pictures to create two additional versions of each, adding either mild or severe acne to the people’s faces. They then performed an experiment with… read on > read on >

The newly approved weight-loss medication known as Zepbound is now available for patients to take, drug maker Eli Lilly announced Tuesday. “Today opens another chapter for adults living with obesity who have been looking for a new treatment option like Zepbound,” Rhonda Pacheco, group vice president of Lilly Diabetes and Obesity, U.S., said in a company news release. “The availability of Zepbound in U.S. pharmacies is the first step, but we have to work hand-in-hand with employers, government and healthcare industry partners to remove barriers and make Zepbound available to those who need it,” Pacheco added. “We are excited to see growing [insurance] coverage in the marketplace, giving millions of Americans access to Zepbound.” It was only last month when the U.S. Food and Drug Administration approved Zepbound as a weight-loss medication. Tirzepatide, the active ingredient in Zepbound, had already been approved by the FDA as a treatment for type 2 diabetes called Mounjaro. To trigger weight loss, tirzepatide mimics two hormones, GLP-1 and GIP, which stimulate the release of insulin in the body. It quells appetite and slows the rate at which food moves through the stomach, helping patients feel full. Novo Nordisk’s weight-loss medication, Wegovy, uses semaglutide, which only focuses on GLP-1. That difference translated to greater weight loss with Zepbound than Wegovy, a recent study found. Zepbound has been found to prompt up to a 20.9%… read on > read on >

In sickness and in health — and in blood pressure, too? A new international study finds that if your blood pressure rises with time, your spouse’s might, also. “Many people know that high blood pressure is common in middle-aged and older adults, yet we were surprised to find that among many older couples, both husband and wife had high blood pressure in the U.S., England, China and India,” said study senior author Dr. Chihua Li, a post-doctoral fellow at the University of Michigan. “For instance, in the U.S., among more than 35% of couples who were ages 50 or older, both had high blood pressure,” Li said in a news release from the American Heart Association (AHA). Li’s team published its findings Dec. 6 in the Journal of the American Heart Association. High blood pressure is a common complaint among Americans, and the risk of hypertension rises with age. According to the AHA, almost half (about 47%) of adult Americans had high blood pressure in 2020, and it contributed to 120,000 deaths that year. In the new study, Li and colleagues looked at rates of high blood pressure among nearly 34,000 heterosexual couples worldwide: 4,000 U.S. couples, 1,100 couples in England, more than 6,500 Chinese couples and over 22,000 Indian couples. Data was collected between 2015 and 2019, depending on the country. High blood pressure… read on > read on >

Folks with a family history of heart disease might benefit from eating more oily fish like salmon, mackerel, herring and sardines, a new study finds. Oily fish contain high levels of omega-3 fatty acids, which cannot be produced by the body and must be obtained from the diet. People’s risk of heart disease increased by more than 40% if they had low levels of omega-3 fatty acids plus a family history of heart problems, a large international study concluded. However, if a person has adequate levels of omega-3 fatty acids, their family heart history increased their risk by just 25%. The results show that heathy habits can overcome genetic risk in some cases, researchers said. “The study suggests that those with a family history of cardiovascular disease have more to gain from eating more oily fish than others,” said lead researcher Karin Leander, an associate professor of epidemiology at the Karolinska Institute in Sweden. Omega-3 fatty acids have been linked to a stronger immune system, reduced inflammation, lower blood pressure and improved cholesterol counts, according to the American Heart Association. For the study, Leander and her colleagues pooled data from more than 40,000 people, nearly 8,000 of whom developed heart problems like unstable angina, heart attack, cardiac arrest and stroke. Levels of omega-3 fatty acids were measured in all study participants. These levels are a… read on > read on >

Patients in the earliest stages of multiple sclerosis might develop certain symptoms that offer an early clue to the degenerative nerve disease, researchers report. Depression, constipation, urinary tract infections and sexual problems are all more likely in MS patients five years before their official diagnosis, compared with people who never develop MS, researchers found. Those conditions are also more likely to occur in people with other autoimmune diseases like lupus or Crohn’s disease, results show. These early signs “would not necessarily lead to earlier diagnosis of the disease in the general population, since these conditions are common and could also be signs of other diseases, but this information could be helpful for people who are at a higher risk of developing MS, such as people with a family history of the disease or those who show signs of MS on brain scans but do not have any symptoms of the disease,” said researcher Dr. Celine Louapre, an associate professor of neurology at Sorbonne University in Paris. MS occurs when the immune system attacks the protective sheath that covers nerve fibers, causing progressive interruption of nerve signals between the brain and the body. For the study, Louapre and her colleagues compared more than 20,000 people newly diagnosed with MS with nearly 55,000 people who do not have MS. Each MS patient was matched with three healthy people… read on > read on >

New research challenges a long-held notion that human newborns enter the world with brains that are significantly less developed than those of other primates. Babies are born extremely helpless and with poor muscle control, and human brains grow much larger and more complex than other species following birth, investigators said. Because of those observations, it’s long been believed that human newborns have brains comparatively less developed than other primates at birth. But that’s a false impression, researchers report in the Dec. 4 issue of the journal Nature Ecology & Evolution. Analysis of brain development patterns in 140 different mammal species has provided new insight into the evolution of human brains, by taking into account factors like fetal gestation and comparative brain size of newborns to adults. “This new work changes the overall understanding around the evolution of human brain development,” said lead researcher Aida Gomez-Robles, an associate professor of anthropology at University College London. “Humans seem so much more helpless when they’re young compared to other primates, not because their brains are comparatively underdeveloped but because they still have much further to go,” Gomez-Robles added in a university news release. Scientists typically judge brain development of different species by comparing the size of their brains as newborns to their brain size as adults, researchers said in background notes. Humans are born with a brain that’s relatively… read on > read on >

Hispanic women who experience spikes in blood pressure while pregnant may also face higher heart risks years later, new research shows. These “hypertensive disorders of pregnancy” (HDP) — conditions such as preeclampsia, eclampsia and gestational hypertension — may even have a greater role to play in certain heart risks than regular high blood pressure, the researchers noted. “These findings emphasize the importance of recognizing HDP as an important risk factor for these future problems,” said researcher Jasmina Varagic. She’s a program officer in the Vascular Biology and Hypertension branch at the National Heart, Lung, and Blood Institute (NHLBI), part of the National Institutes of Health. According to Varagic’s team, rates of HDP more than doubled among pregnant women in the United States between 2007 and 2019. The increase was highest among pregnant Hispanic women, resulting in 60 cases of some form of hypertensive disorder per every 1,000 live births. High blood pressure during pregnancy does not bode well for blood pressure long after the baby is born, the researchers noted. Prior studies have shown that HDP raises the odds of having chronic high blood pressure 10-fold. In the new study, Varagic’s group tracked the health of nearly 5,200 Hispanic women who’d had at least one child and who averaged about 59 years of age. The researchers took special scans of each woman’s heart, looking at… read on > read on >

People with epilepsy suffer quicker declines in thinking than people without the brain disorder, particularly if they also have risk factors like high blood pressure or diabetes, a new study finds. The difference was significant: Over the course of the 14-year study, those with epilepsy experienced a 65% to 70% faster decline in memory and thinking skills. On top of that, having risk factors for heart disease pushed that percentage 20% higher. “While epilepsy itself is associated with [mild cognitive impairment] and dementia, this risk is substantially magnified in those who also have high blood pressure, diabetes or other cardiovascular risk factors,” said lead researcher Dr. Ifrah Zawar, an assistant professor of neurology at the University of Virginia in Charlottesville. Researchers said their study is unique because it tracked the transition to mild cognitive impairment and dementia in more than 13,700 people who started the study with healthy brains. The participants were recruited at 39 Alzheimer’s disease centers across the United States between September 2005 and December 2021. Fewer than 1% had epilepsy, researchers said. The rate of decline from mild cognitive impairment to dementia was the same in patients with or without epilepsy. The researchers speculate that’s probably because heart risk factors play a much bigger role than epilepsy in the later stages of dementia. The findings were presented Friday at the American Epilepsy… read on > read on >

Unhealthy air from wildfires is causing hundreds of additional deaths in the western United States every year, a new study claims. Wildfires have undercut progress made in cleaning America’s air, and between 2000 and 2020 caused an increase of 670 premature deaths each year in the West, researchers report Dec. 4 in The Lancet Planetary Health journal. “Our air is supposed to be cleaner and cleaner, due mostly to EPA regulations on emissions, but the fires have limited or erased these air-quality gains,” said lead researcher Jun Wang, chair of chemical and biochemical engineering at the University of Iowa. “In other words, all the efforts for the past 20 years by the EPA to make our air cleaner basically have been lost in fire-prone areas and downwind regions,” Wang added in a university news release. “We are losing ground.” For this study, researchers calculated the concentration of airborne black carbon, a fine-particle air pollutant linked to respiratory and heart disease, across the continental United States. For their calculations, researchers used an AI program to analyze air quality data from satellites and ground-based stations. Premature deaths were calculated using a formula that took into account average lifespan, black carbon exposure and population density. “This is the first time to look at black carbon concentrations everywhere, and at one-kilometer resolution,” Wang says. They found that black carbon… read on > read on >

Teenagers with epilepsy are more likely to have an eating disorder than those not suffering from the brain disease, a new study shows. About 8.4% of children ages 10 to 19 treated at a Boston epilepsy clinic had eating disorders, three times the national average of 2.7% of teens with an eating disorder, researchers found. “Adolescents with epilepsy may feel a loss of control because they don’t know when they’ll have a seizure,” said lead researcher Dr. Itay Tokatly Latzer, an epilepsy fellow at Boston Children’s Hospital. “Controlling what they eat or don’t eat can presumably make them feel they have regained some control,” Tokatly Latzer added in a hospital news release. “This is one of the ways epilepsy may lead to eating disorders, in people who have a biological or psychological predisposition to develop eating disorders.” For the study, Tokatly Latzer and colleagues analyzed data on 1,740 teens treated at least once at Boston Children’s Epilepsy Center for any conditions involving seizures between 2013 and 2022. None of the teens had an intellectual disability or autism. Of those children, 146 were diagnosed with an eating disorder. During the 10-year-period, the number of teens treated at the center who had eating disorders increased annually, rising from 12 in 2013 to 22 in 2022. Anorexia was more common than either bulimia or binge eating among teens… read on > read on >

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All Sauce from Weekly Gravy:

Acne in Adults Can Bring Stigma at Work and Socially

New Weight-Loss Drug Zepbound Is Now Available, Company Says

As One Spouse’s Blood Pressure Rises, So Does the Other’s: Study

Folks at High Risk of Heart Disease May Gain From Eating Mackerel, Tuna

Mind, Body Symptoms Can Precede MS Diagnosis for Years

Newborns’ Brains Aren’t ‘Undeveloped’ Compared to Those of Infant Monkeys, Chimps

High Blood Pressure in Pregnancy Tied to Long-Term Heart Trouble for Hispanic Women

Cognitive Decline May Come Earlier for People With Epilepsy

Wildfires Are Undoing Gains Made Against Air Pollution

Teens With Epilepsy Face Higher Odds for Eating Disorders