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WEDNESDAY, Nov. 15, 2023 (Healthday News) — As U.S. suicide rates continue to rise, new government data shows older men have become the most susceptible. In a report published Wednesday, researchers from the U.S. Centers for Disease Control and Prevention found there were about 30 suicide deaths for every 100,000 men aged 55 and older in 2021. That number is more than double the overall rate of just over 14 suicide deaths for every 100,000 people that year. The older a man, the greater his risk for suicide: Those 85 and older saw 56 suicide deaths for every 100,000 people, a statistic that surpassed any other age group. Suicide is complex, Dr. Yeates Conwell, a psychiatry professor at the University of Rochester, told CNN. Five factors can fuel suicide risk — depression, disease, disability, disconnection and deadly means — and these risk factors can be “relatively more salient for older adults,” he said. “Imagine a Venn diagram with these five circles, each representing one of those ‘Ds’ that overlap. The more of the intersecting circles one is in, the greater the risk,” said Conwell, who also leads a geriatric psychiatry program and co-directs the university’s Center for the Study and Prevention of Suicide. A combination of more physical illness and disability, along with more social isolation and more loss, leaves older adults more vulnerable to suicide, he…  read on >  read on >

Oral nicotine pouches might be marketed as an alternative to cigarettes, but they do little to curb smokers’ nicotine cravings, a new study finds. The pouches – which contain nicotine powder and other flavorings, but no tobacco leaf – take too long to provide the nicotine “spike” that eases cravings, researchers report in the Nov. 15 issue of journal Addiction. Current smokers still get a much greater nicotine spike and much sharper relief from craving symptoms when they take a puff than when they use either low- or high-dose nicotine pouches, the results showed. The spike of nicotine from smoking occurs within about five minutes, said lead researcher Brittney Keller-Hamilton, of Ohio State University’s Cancer Control Program. By comparison, nicotine pouches take 30 minutes to an hour to hit peak effectiveness, researchers said. It’s reasonable to see how the instant gratification from cigarette smoking would be more appealing than oral nicotine pouches for smokers deep in the need for a nicotine fix, Keller-Hamilton said. At the same time, researchers are concerned that the pouches could appeal to young people, increasing nicotine addiction in a younger population while doing nothing to stem cancer risk among smokers. “Our challenge is to approach regulation of nicotine pouches to limit their appeal among young people while making them more appealing to adult smokers who would see health benefits by…  read on >  read on >

Retatrutide, an experimental weight-loss drug that could compete against blockbusters Wegovy and Zepbound, may work wonders for obese folks with liver disease, new research shows. A wider study, published in June, found that retatrutide helped obese people lose about a quarter of their starting weight over an 11-month period. Now, findings from a subset of participants in that trial showed that retatrutide also culled excessive fat from around the livers of obese people — essentially curing many from a dangerous condition called fatty liver disease. The research was funded by Eli Lilly and Co., which is developing retatrutide. “The implications of this trial are, we could wipe out the fat very early in the course of this disease, before it becomes a real threat to the liver and, potentially, reduce the long-term cardiac, metabolic, renal [kidney] and liver-related harm from obesity,” said sub-study lead Dr. Arun Sanyal, of Virginia Commonwealth University (VCU) in Richmond. “We are encouraged by these results and how they can potentially help tackle a disease that is currently without any approved therapies,” added Sanyal, who directs VCU’s Stravitz-Sanyal Institute for Liver Disease and Metabolic Health. The weight-loss results from the larger trial were published in the New England Journal of Medicine in June. The newer data, from a subset of patients with liver disease, was presented Nov. 13 at a meeting…  read on >  read on >

Pesticide exposure appears to be linked to lower sperm concentrations in men around the world, a new large-scale evidence review has concluded. A review of 25 studies spanning nearly 50 years found consistent links between lower sperm concentrations and two widely used classes of insecticides, organophosphates and N-methyl carbamates, researchers said. “This review is the most comprehensive review to date,” said senior researcher Melissa Perry, dean of the George Mason University College of Public Health in Fairfax, Va. “The evidence available has reached a point that we must take regulatory action to reduce insecticide exposure.” Perry’s team systematically reviewed 25 human studies of occupational and environmental insecticide exposure, conducted over the past half-century. The findings, published Nov. 15 in the journal Environmental Health Perspectives, revealed evidence of robust associations between insecticide exposure and lower sperm concentration. “Understanding how insecticides affect sperm concentration in humans is critical given their ubiquity in the environment and documented reproductive hazards,” said co-researcher Lauren Ellis, a doctoral student at Northeastern University. “Insecticides are a concern for public health and all men, who are exposed primarily through the consumption of contaminated food and water.” More information The Mayo Clinic has more on healthy sperm. SOURCE: George Mason University, news release, Nov. 15, 2023  read on >

Social media platforms are spouting a steady stream of unsafe skin care trends, according to the American Academy of Dermatology. This is National Healthy Skin Month, and board-certified dermatologists are putting a spotlight on five unsafe practices you might come across while perusing social media. Performing cosmetic treatments at home People are microneedling, injecting fillers and using lasers to remove unwanted hair in videos taken at home. “This is something I find really concerning,” said Dr. Sara Moghaddam, a board-certified dermatologist in Selbyville, Del. “For example, at-home microneedling, also known as derma-rolling, is dangerous due to risk of infections and improper techniques.” Dr. Oyetewa Oyerinde, an assistant professor of dermatology and director of the Skin of Color Clinic at Baylor College of Medicine in Houston, warns that an unsafe cosmetic procedure can look perfectly harmless on someone’s social media platform. “My patients will see people who document their entire experience performing a cosmetic procedure on TikTok or on Instagram,” Oyerinde said. “I tell patients, even if their immediate effect looks good to you — and they may be using filters and other things to make it look good — you have no idea if they ended up in the emergency room afterward because of a bad reaction.” Trying nasal tanning spray Self-tanner applied to the skin is a safe way to gain a lovely glow,…  read on >  read on >

TUESDAY, Nov. 14, 2023 (Healthday News) — There is nothing worse for your heart than sitting, a new study confirms. “The big takeaway from our research is that while small changes to how you move can have a positive effect on heart health, intensity of movement matters,” said study first author Dr. Jo Blodgett, a research fellow with University College London’s Institute of Sport, Exercise & Health. “The most beneficial change we observed was replacing sitting with moderate to vigorous activity — which could be a run, a brisk walk or stair climbing — basically any activity that raises your heart rate and makes you breathe faster, even for a minute or two,” Blodgett added in a university news release. However, even standing and sleeping beat sitting when it came to heart health, the study found. Heart disease is the leading cause of mortality worldwide. In 2021, it was responsible for one in three deaths, and the number of people living with heart disease across the world has doubled since 1997, the researchers said. “We already know that exercise can have real benefits for your cardiovascular health and this encouraging research shows that small adjustments to your daily routine could lower your chances of having a heart attack or stroke,” said James Leiper, associate medical director at the British Heart Foundation, which funded the research.…  read on >  read on >

Controlled forest burns can prevent the sort of high-intensity wildfires that have plagued the Western U.S. and Canada as a result of climate change, a new study argues. A low-intensity fire in the mixed conifer forests of California provides an estimated 60% reduction in the risk of a catastrophic wildfire, and that effect lasts at least six years, researchers report in the journal Science Advances. Controlled burns also could provide a smaller but still significant reduction in risk in oak-dominated forests, researchers added. “I’m hopeful that policymakers will rely on this work as motivation and support for the scale-up of beneficial fire as a key strategy in preventing wildfire catastrophes,” co-author Michael Wara, director of the Climate and Energy Policy Program at the Stanford Woods Institute for the Environment, said in a Stanford news release. “Beneficial fire is not without its own risks – but what our study shows is just how large and long-lasting the benefits are of this crucial risk reduction strategy,” Wara said. The U.S. Forest Service has proposed treating about 50 million acres of forest through a mixture of “fuel treatment strategies,” which can include burns as well as thinning, pruning and logging to reduce the amount of combustible vegetation, researchers noted. For the study, researchers reviewed two decades of satellite monitoring of wildfires covering nearly 25 million acres of California…  read on >  read on >

The party drug and anesthetic ketamine is starting to show promise in trials as a treatment for depression. But new research also suggests that hundreds of U.S. clinics may be misleading consumers, hawking off-label and unapproved ketamine to treat a variety of mental health and pain conditions. “These are expensive treatments for which patients generally must pay out of pocket and the evidence base is often not robust for many of the advertised uses,” said co-lead study author Michael DiStefano, an assistant professor in the department of clinical pharmacy at Colorado University’s Skaggs School of Pharmacy. “It is important that people considering these treatments are provided with an accurate and balanced statement of the possible risks and benefits.” In the study published Nov. 7 in the journal JAMA Network Open, the researchers noted that ketamine delivered intravenously is not yet approved by the U.S. Food and Drug Administration to treat any mental health condition, but it is sometimes used off-label for such use. Ketamine in pill form isn’t approved to treat anything, either, but is often advertised to produce a hallucinogenic experience at home, the researchers said. Using six national ketamine databases, DiStefano’s team tracked how ketamine is being sold. They identified online direct-to-consumer ketamine advertisers who had websites plus at least one clinic in Maryland. The researchers found 17 advertisers operating across 26 locations…  read on >  read on >

MONDAY, Nov. 13, 2023 — In an unexpected finding, new research suggests that antibodies arising from common food allergies may also raise risks for heart trouble. These IgE antibodies didn’t even have to be present in quantities high enough to produce an actual food allergy to have this unhealthy effect on the heart, noted a team from the University of Virginia Health (UVA) System, in Charlottesville. “What we looked at here was the presence of IgE antibodies to food that were detected in blood samples,” researcher Dr. Jeffrey Wilson said in a UVA news release. “We don’t think most of these subjects actually had overt food allergy, thus our story is more about an otherwise silent immune response to food.” “While these responses may not be strong enough to cause acute allergic reactions to food, they might nonetheless cause inflammation and over time lead to problems like heart disease,” said Wilson, an allergy and immunology expert at the UVA School of Medicine. All of this could mean trouble for a large swath of the population: According to the researchers, about 15% of adults produce IgE antibodies in response to cow’s milk, peanuts and other foods. Not everyone who produces the antibodies will have a symptomatic food allergy, however. In their research, Wilson’s team collected data on almost 5,400 participants involved in either a national U.S.…  read on >  read on >

The gap in life expectancy between American men and women is now the biggest it has been since the mid-1990s — almost six years. The pandemic and opioid overdoses are key factors in the gender difference in longevity, said researchers from the University of California, San Francisco (UCSF) and Harvard University T.H. Chan School of Public Health. “There’s been a lot of research into the decline in life expectancy in recent years, but no one has systematically analyzed why the gap between men and women has been widening since 2010,” said first study author Dr. Brandon Yan, a resident in internal medicine at UCSF. In 2021, the gender gap in life expectancy rose to 5.8 years, its largest since 1996, he and his colleagues report. In 2010, the gap was its smallest in recent history, 4.8 years. Life expectancy in the United States was 76.1 years in 2021. That’s down from 78.8 years in 2019 and 77 years in 2020. Researchers cited the pandemic as the biggest factor in the widening gender gap; it took a heavier toll on men. Unintentional injuries and poisonings (mostly drug overdoses), accidents and suicide were other contributors. Another factor in Americans’ shrinking lifespan: so-called “deaths of despair.” That’s a nod to the rise in deaths owing to such causes as suicide, drug use disorders and alcoholic liver disease. These…  read on >  read on >