All Sauce from Weekly Gravy:

Social media platforms are spouting a steady stream of unsafe skin care trends, according to the American Academy of Dermatology. This is National Healthy Skin Month, and board-certified dermatologists are putting a spotlight on five unsafe practices you might come across while perusing social media. Performing cosmetic treatments at home People are microneedling, injecting fillers and using lasers to remove unwanted hair in videos taken at home. “This is something I find really concerning,” said Dr. Sara Moghaddam, a board-certified dermatologist in Selbyville, Del. “For example, at-home microneedling, also known as derma-rolling, is dangerous due to risk of infections and improper techniques.” Dr. Oyetewa Oyerinde, an assistant professor of dermatology and director of the Skin of Color Clinic at Baylor College of Medicine in Houston, warns that an unsafe cosmetic procedure can look perfectly harmless on someone’s social media platform. “My patients will see people who document their entire experience performing a cosmetic procedure on TikTok or on Instagram,” Oyerinde said. “I tell patients, even if their immediate effect looks good to you — and they may be using filters and other things to make it look good — you have no idea if they ended up in the emergency room afterward because of a bad reaction.” Trying nasal tanning spray Self-tanner applied to the skin is a safe way to gain a lovely glow,…  read on >  read on >

TUESDAY, Nov. 14, 2023 (Healthday News) — There is nothing worse for your heart than sitting, a new study confirms. “The big takeaway from our research is that while small changes to how you move can have a positive effect on heart health, intensity of movement matters,” said study first author Dr. Jo Blodgett, a research fellow with University College London’s Institute of Sport, Exercise & Health. “The most beneficial change we observed was replacing sitting with moderate to vigorous activity — which could be a run, a brisk walk or stair climbing — basically any activity that raises your heart rate and makes you breathe faster, even for a minute or two,” Blodgett added in a university news release. However, even standing and sleeping beat sitting when it came to heart health, the study found. Heart disease is the leading cause of mortality worldwide. In 2021, it was responsible for one in three deaths, and the number of people living with heart disease across the world has doubled since 1997, the researchers said. “We already know that exercise can have real benefits for your cardiovascular health and this encouraging research shows that small adjustments to your daily routine could lower your chances of having a heart attack or stroke,” said James Leiper, associate medical director at the British Heart Foundation, which funded the research.…  read on >  read on >

Controlled forest burns can prevent the sort of high-intensity wildfires that have plagued the Western U.S. and Canada as a result of climate change, a new study argues. A low-intensity fire in the mixed conifer forests of California provides an estimated 60% reduction in the risk of a catastrophic wildfire, and that effect lasts at least six years, researchers report in the journal Science Advances. Controlled burns also could provide a smaller but still significant reduction in risk in oak-dominated forests, researchers added. “I’m hopeful that policymakers will rely on this work as motivation and support for the scale-up of beneficial fire as a key strategy in preventing wildfire catastrophes,” co-author Michael Wara, director of the Climate and Energy Policy Program at the Stanford Woods Institute for the Environment, said in a Stanford news release. “Beneficial fire is not without its own risks – but what our study shows is just how large and long-lasting the benefits are of this crucial risk reduction strategy,” Wara said. The U.S. Forest Service has proposed treating about 50 million acres of forest through a mixture of “fuel treatment strategies,” which can include burns as well as thinning, pruning and logging to reduce the amount of combustible vegetation, researchers noted. For the study, researchers reviewed two decades of satellite monitoring of wildfires covering nearly 25 million acres of California…  read on >  read on >

The party drug and anesthetic ketamine is starting to show promise in trials as a treatment for depression. But new research also suggests that hundreds of U.S. clinics may be misleading consumers, hawking off-label and unapproved ketamine to treat a variety of mental health and pain conditions. “These are expensive treatments for which patients generally must pay out of pocket and the evidence base is often not robust for many of the advertised uses,” said co-lead study author Michael DiStefano, an assistant professor in the department of clinical pharmacy at Colorado University’s Skaggs School of Pharmacy. “It is important that people considering these treatments are provided with an accurate and balanced statement of the possible risks and benefits.” In the study published Nov. 7 in the journal JAMA Network Open, the researchers noted that ketamine delivered intravenously is not yet approved by the U.S. Food and Drug Administration to treat any mental health condition, but it is sometimes used off-label for such use. Ketamine in pill form isn’t approved to treat anything, either, but is often advertised to produce a hallucinogenic experience at home, the researchers said. Using six national ketamine databases, DiStefano’s team tracked how ketamine is being sold. They identified online direct-to-consumer ketamine advertisers who had websites plus at least one clinic in Maryland. The researchers found 17 advertisers operating across 26 locations…  read on >  read on >

MONDAY, Nov. 13, 2023 — In an unexpected finding, new research suggests that antibodies arising from common food allergies may also raise risks for heart trouble. These IgE antibodies didn’t even have to be present in quantities high enough to produce an actual food allergy to have this unhealthy effect on the heart, noted a team from the University of Virginia Health (UVA) System, in Charlottesville. “What we looked at here was the presence of IgE antibodies to food that were detected in blood samples,” researcher Dr. Jeffrey Wilson said in a UVA news release. “We don’t think most of these subjects actually had overt food allergy, thus our story is more about an otherwise silent immune response to food.” “While these responses may not be strong enough to cause acute allergic reactions to food, they might nonetheless cause inflammation and over time lead to problems like heart disease,” said Wilson, an allergy and immunology expert at the UVA School of Medicine. All of this could mean trouble for a large swath of the population: According to the researchers, about 15% of adults produce IgE antibodies in response to cow’s milk, peanuts and other foods. Not everyone who produces the antibodies will have a symptomatic food allergy, however. In their research, Wilson’s team collected data on almost 5,400 participants involved in either a national U.S.…  read on >  read on >

The gap in life expectancy between American men and women is now the biggest it has been since the mid-1990s — almost six years. The pandemic and opioid overdoses are key factors in the gender difference in longevity, said researchers from the University of California, San Francisco (UCSF) and Harvard University T.H. Chan School of Public Health. “There’s been a lot of research into the decline in life expectancy in recent years, but no one has systematically analyzed why the gap between men and women has been widening since 2010,” said first study author Dr. Brandon Yan, a resident in internal medicine at UCSF. In 2021, the gender gap in life expectancy rose to 5.8 years, its largest since 1996, he and his colleagues report. In 2010, the gap was its smallest in recent history, 4.8 years. Life expectancy in the United States was 76.1 years in 2021. That’s down from 78.8 years in 2019 and 77 years in 2020. Researchers cited the pandemic as the biggest factor in the widening gender gap; it took a heavier toll on men. Unintentional injuries and poisonings (mostly drug overdoses), accidents and suicide were other contributors. Another factor in Americans’ shrinking lifespan: so-called “deaths of despair.” That’s a nod to the rise in deaths owing to such causes as suicide, drug use disorders and alcoholic liver disease. These…  read on >  read on >

MONDAY, Nov. 13, 2023 (Healthday News) — In a finding that could change the landscape of heart disease care, the wildly popular weight-loss drug Wegovy has proved its mettle in protecting the heart after lowering the risk of cardiac problems in patients by 20%. The results from this large, international study had been eagerly awaited by scientists and doctors alike. Why? It is the first to show that Wegovy’s therapeutic powers may extend to the cardiovascular system, helping prevent a heart attack, stroke or a heart-related death in people who already have heart disease but not diabetes. “It moves from a kind of therapy that reduces body weight to a therapy that reduces cardiovascular events,” study author Dr. Michael Lincoff, vice chairman for research in the department of cardiovascular medicine at the Cleveland Clinic, told the Associated Press. A high-dose version of the diabetes drug Ozempic, which already has been shown to lower the risk of heart problems in people who have diabetes, Wegovy seems to do the same for heart patients who don’t have the blood sugar disease. Dr. Francisco Lopez-Jimenez, a heart expert at the Mayo Clinic, told the AP that he believes the new findings will alter heart treatment guidelines and “dominate the conversation” for years to come. “This is the population who needs the medicine the most,” said Lopez-Jimenez, who wasn’t…  read on >  read on >

MONDAY, Nov. 13, 2023 (Healthday News) — Two new gene-editing treatments that target dangerously high levels of cholesterol in people with a genetic predisposition to the condition were found safe and effective in new, groundbreaking research. While powerful drugs like statins can help manage cholesterol in most people, they can’t treat those who have genes that predispose them to heart troubles. But the duo of studies, presented Sunday at the American Heart Association (AHA) annual meeting in Philadelphia, may one day change that. Both treatments will need years of additional research before the U.S. Food and Drug Administration would even consider approving them, but that didn’t dampen the excitement among heart experts. “There is no way to categorize this other than revolutionary,” Dr. Hugh Cassiere, director for critical care services at South Shore University Hospital, Northwell Cardiovascular Institute, in New York, told NBC News. He was not involved with either study. One of the treatments, from Boston-based Verve Therapeutics, uses a gene-editing approach that targets the PCSK9 gene, making a tiny change to the gene. The effect is akin to a permanent eraser, deleting the gene’s ability to fuel a rise in cholesterol levels, Verve co-founder and CEO Dr. Sekar Kathiresan told NBC News. In theory, the one-time treatment should last a lifetime. “Instead of daily pills or intermittent injections over decades to lower bad cholesterol, this…  read on >  read on >

Cutting out just one teaspoon of salt every day lowers blood pressure almost as much as medication does, new research shows. Investigators said theirs is one of the largest studies ever to include people taking high blood pressure meds in a look at the effect of reducing dietary intake of sodium. “We found that 70-75% of all people, regardless of whether they are already on blood pressure medications or not, are likely to see a reduction in their blood pressure if they lower the sodium in their diet,” said study co-author Norrina Allen, a professor of preventive medicine at Northwestern University Feinberg School of Medicine in Chicago.   She said researchers previously didn’t know if people already on blood pressure meds could lower their blood pressure even more by reducing their sodium intake. In the study, middle-aged to elderly participants reduced their salt intake by about 1 teaspoon a day.  “The result was a decline in systolic blood pressure by about 6 millimeters of mercury (mm Hg), which is comparable to the effect produced by a commonly utilized first-line medication for high blood pressure,” said co-principal investigator Dr. Deepak Gupta, an associate professor of medicine at Vanderbilt University Medical Center, in Nashville, Tenn.  Systolic blood pressure is the pressure in your arteries as your heart beats. It’s the first number in a blood pressure reading.…  read on >  read on >

Young people who smoke and have prediabetes have triple the risk of suffering a stroke, a new study shows. Overall, hospitalized tobacco users with prediabetes had a 3.3 times higher risk that they were in the hospital due to a stroke, after researchers accounted for other risk factors. The findings “warrant early screening and prevention strategies for prediabetes in young tobacco users in order to curtail their risk of stroke,” said lead researcher Dr. Advait Vasavada, a resident in family medicine at the University of Nebraska Medical Center in Omaha. Vasavada plans to present the findings at the American Heart Association (AHA) annual meeting, being held from Nov. 11-13 in Philadelphia. Findings presented at a medical meeting should be considered preliminary until published in a peer-reviewed journal. For the study, Vasavada’s research team analyzed records for more than 1 million tobacco users ages 18 to 44 who were admitted to a U.S. hospital in 2019. All the young adults included in the study were considered healthy, with no heart disease risk factors like high blood pressure, type 2 diabetes, elevated cholesterol or obesity. However, their charts showed that all were long-term tobacco users who were dependent on nicotine and had a hard time cutting back or quitting. Looking more closely, researchers found that about two out of every 1,000 also had prediabetes – elevated blood…  read on >  read on >