All Sauce from Weekly Gravy:

Research into a possible link between childhood health problems and natural gas wells in western Pennsylvania is wrapping up with some answers. Children who lived near these wells were more likely to develop rare lymphoma, the research found. In addition, residents of all ages near the wells had increased risk of severe asthma reactions, the Associated Press reported. The AP reported that researchers said their look at preterm births and birth weights among families living near gas wells yielded mixed results similar to those in other studies. There is a possibility that gas production might reduce birth weights by less than an ounce on average. Raina Rippel, former director of the Southwest Pennsylvania Environmental Health Project, called the findings the “tip of the toxic iceberg.” “We are only just beginning to understand what is out there,” she told the AP, warning that there is “a lot more cancer waiting in the wings.” The researchers found that children who lived within 1 mile of a well had five to seven times the risk for lymphoma compared to children who lived at least 5 miles from a well. That equates to 60 to 84 children per million with lymphoma for kids living near wells, compared to 12 per million for those living farther away, the AP reported. The association with severe asthma was found for times when…  read on >  read on >

America’s emergency rooms are being flooded by children suffering from psychiatric emergencies like anxiety, depression and suicidal thoughts or attempts, a new joint report from three leading medical associations warns. This surge in pediatric mental health emergencies has overwhelmed ERs in the United States, says the joint paper from the American Academy of Pediatrics (AAP), American College of Emergency Physicians (ACEP) and Emergency Nurses Association (ENA). Unfortunately, the kids coming to the ER are less likely to receive the ongoing mental health care they truly need, said lead author Dr. Mohsen Saidinejad, director of pediatric emergency medicine at the Ronald Reagan UCLA Medical Center. “The ER has become a de facto referral center for all of these problems, and there’s too many of them for the emergency department to manage,” said Saidinejad, a member of the AAP and ACEP committees on pediatric emergency medicine. “That is not who we are as ER physicians. We are not mental health professionals. We cannot provide definitive care. “We can screen, we can identify those at harm risk, but that’s about it, so the ER is really not the most appropriate place to manage these cases,” Saidinejad said. “And I think we are becoming that because there isn’t any other place for these kids to be sent.” The joint policy statement and technical report were published Aug. 16 in…  read on >  read on >

Having good fitness while young can really pay off when it comes to cancer risk later in life. New research found that cardiorespiratory fitness — the ability to do aerobic exercise — was associated with up to 42% lower risk of nine cancers, including head and neck, esophagus, stomach, pancreas, liver, colon, kidney and lung. Researchers used Swedish registry data up to the end of 2019, covering background information, medical diagnoses and deaths for male conscripts who started their military service between 1968 and 2005. The conscripts were age 16 to 25 when they started their service and had a battery of assessments at that time, including height, weight (body mass index), blood pressure, muscular strength and cardiorespiratory fitness. Those who had a low level of cardiorespiratory fitness were slightly more likely to be obese and more likely to have a history of alcohol and substance misuse. They were also more likely to have parents with lower educational attainment than their counterparts who had a higher fitness level. More than 365,000 conscripts had a low level of cardiorespiratory fitness. More than 519,000 had a moderate level and nearly 341,000 had a high level. The final analysis included more than 1 million men, about 7% of whom later developed cancer in at least one site during an average monitoring period of 33 years. Those with higher…  read on >  read on >

What researchers call ‘social factors’ are largely responsible for Black Americans having a greater risk of death from heart disease than whites, according to a new study. Among the social factors that contribute to this racial disparity are unemployment, low income, lack of regular access to health care and lack of a partner, Tulane University researchers said. “For so many years we have focused on smoking, diet, physical activity, obesity, [high blood pressure], diabetes and high cholesterol — and we know those are important” for preventing heart disease, said lead author Dr. Jiang He, chair in epidemiology at Tulane University’s School of Public Health and Tropical Medicine in New Orleans. He added he was surprised that the Black-white difference in heart-disease death rates owes mainly to social factors. Black Americans are 54% more likely to die of heart disease than white Americans, the study found. This is true even with a substantial overall reduction in heart disease deaths nationwide. The study used health data from more than 50,000 U.S. adults. The researchers examined links between heart-related deaths and clinical risk factors like obesity, diabetes and high blood pressure as well as lifestyle factors, including smoking, unhealthy diet, lack of exercise and too little or too much sleep. Researchers also considered social risk factors, such as unemployment, low income, food insecurity, limited education, lack of private…  read on >  read on >

“She’s cheer captain and I’m on the bleachers,” Taylor Swift laments to her popular crush in the song “You Belong With Me.” The lyrics of longing to fit in at school reflect an old trope re-confirmed by a new study that compared teens in the United States and Lithuania: Kids seen by their peers as less athletic or less attractive have a harder time than their seemingly picture-perfect classmates. “A long time ago, maybe 60 years ago, there was a really famous study done by sociologist James S. Coleman who found that, much to the chagrin of grown-ups, the most popular, the most important students in high schools were the athletic boys and the attractive girls,” said Brett Laursen, a professor of psychology at Florida Atlantic University and senior author of the new study. “And over the years there have been some correlations that find that children who are not attractive and children who are not athletic struggle a bit. They still have social difficulties and emotional problems,” he added. The new study examines why being outside the so-called “in crowd” at school can lead to adjustment problems. For the study, 300 girls and 280 boys attending public middle schools in the United States and Lithuania self-reported alcohol misuse three times during an academic year. Athleticism, attractiveness, unpopularity and peer rejection were also assessed through…  read on >  read on >

Men who have a rare cancer of the penis may have a new treatment option, according to researchers who found promise in immunotherapy. This new study focused on cancer that was locally advanced or had spread (metastasized). The investigators found that immune checkpoint inhibitors offered promising benefits for some patients with advanced penile squamous cell carcinoma. “These findings provide encouraging evidence that immune checkpoint inhibitors can be effective in treating a subset of patients with penile squamous cell carcinoma,” said study co-author Dr. Amin Nassar, a member of Yale Cancer Center in New Haven, Conn., and clinical fellow at Yale School of Medicine. “We believe that further translational studies and biomarker-based research are essential to identify patients most likely to benefit from this therapy and improve the outcomes for individuals with penile cancer,” he explained in a Yale news release. For the study, the researchers focused on 92 patients who had this rare cancer between 2015 and 2022. The most common immunotherapy drugs administered were pembrolizumab, nivolumab and cemiplimab. Some patients were treated with a combination of nivolumab and ipilimumab. About 13% of all patients and 35% of men with metastases limited to lymph nodes, responded to the drugs. The average overall survival rate was 9.8 months, according to the report. Twenty-nine percent of patients had adverse reactions to treatment. “The study highlights the importance…  read on >  read on >

While vast quantities of peels from the aloe vera plant are thrown out every year as agricultural waste, this natural ingredient has potential to be a powerful insecticide, new research suggests. “It’s likely that millions of tons of aloe peels are disposed of globally every year,” said principal investigator Debasish Bandyopadhyay, from the University of Texas Rio Grande Valley. “We wanted to find a way to add value and make them useful.” The plant’s rinds can naturally ward off bugs because of several bioactive compounds found in extracts from the peels. The researchers will present their results this week at the fall meeting of the American Chemical Society, held online and in San Francisco. Bandyopadhyay noticed when he was visiting a local aloe vera production center, that insects left the aloe leaves alone, even as they attacked the leaves of other plants. He asked the CEO of the company if he could take the rinds back to his lab. While some home gardeners have begun to use aloe gel as an ingredient in natural pesticides, these recipes don’t always include the peels. Currently, aloe peels are typically used to create biomass to improve soil quality at aloe farms. However, this rotting agricultural waste can release methane and other greenhouse gases into the atmosphere, contributing to global climate change. Conversely, recycling the peels to develop a…  read on >  read on >

Mosquitoes can be a big pest, leaving behind itchy bumps on skin and potentially spreading serious diseases, such as West Nile virus. Sam Telford III is a professor of infectious disease and global health at Cummings School of Veterinary Medicine at Tufts University and a commissioner for the Central Massachusetts Mosquito Control Project. Some counties in his state have detected West Nile virus this summer, and he said the risk will peak in the next few weeks. That’s why it’s important to protect yourself from mosquitoes. But some products meant to deter them work, and others don’t do the job. What works & doesn’t Citronella, for example, is less effective than other products such as DEET, according to Telford. Patio appliances that heat repellents to keep groups safe outdoors were shown to be highly effective against four species of mosquitoes. Wearables, however, don’t reduce mosquitoes’ attraction to humans, Telford pointed out. While some think wearing long sleeves and long pants will help, keep in mind that mosquitoes can bite through tight-fitting clothing if it’s made of thin material. A better alternative is to wear loose-fitting clothing that has been treated with an insecticide like permethrin (0.5%). Use caution with clothing that is still wet from treatment. It is toxic to cats. Insect repellents with active ingredients such as DEET, picaridin, IR3535 or oil of lemon…  read on >  read on >

A more personalized approach to exercise may be necessary, claims a new study that found fat burning varied widely between individuals. Even worse, this rate often does not align with the “fat-burning zone” on commercial exercise machines, the researchers added. Clinical exercise testing, a diagnostic procedure to measure a person’s physiological response to exercise, may be a more useful tool, the study authors said. “People with a goal of weight or fat loss may be interested in exercising at the intensity which allows for the maximal rate of fat burning. Most commercial exercise machines offer a ‘fat-burning zone’ option, depending upon age, sex and heart rate,” said lead study author Hannah Kittrell. She is a PhD candidate at Icahn Mount Sinai in the Augmented Intelligence in Medicine and Science laboratory, in New York City. “However, the typically recommended fat-burning zone has not been validated, thus individuals may be exercising at intensities that are not aligned with their personalized weight-loss goals,” Kittrell said in a Mount Sinai news release. The researchers noted that the term FATmax is sometimes used to represent the exercise intensity and associated heart rate at the time when the body reaches its highest fat-burning rate during aerobic exercise. Fat is a significant fuel source at this point. For the study, the investigators compared heart rate at FATmax, as measured during a clinical…  read on >  read on >

Psilocybin, the active ingredient in “magic” mushrooms, is getting renewed interest as a potential treatment for various health conditions. Now, a new research review argues that migraines should be added to that list. Psilocybin mushrooms have long been used recreationally as hallucinogens — meaning they alter users’ perceptions of their surroundings. That can lead to euphoria on one end of the scale, or — if things go badly — anxiety, panic or dangerous hallucinations. Medical research into psychedelics like psilocybin and LSD began in the 1950s, and then famously ended after a surge in recreational use by the 1960s “counterculture.” But recent years have seen a new interest in the drugs as medical therapy. Researchers at institutions such as Johns Hopkins University, New York University and the University of California are studying psilocybin as a treatment for conditions like depression, addiction and eating disorders. While most of the research is focused on psychiatric conditions, psilocybin has also shown hints of promise against cluster headaches and migraines. In the new review, published recently in the journal Current Pain and Headache Reports, Dr. Emmanuelle Schindler, an assistant professor of neurology at Yale School of Medicine, describes the research done so far. That includes her own 2021 pilot trial, where Schindler and her colleagues tested the effects of psilocybin — given under medical supervision — in 10 patients…  read on >  read on >