All Sauce from Weekly Gravy:

When you have COVID-19, when are you most infectious? Researchers are getting closer to an answer, with a new study finding that folks exhale the highest amounts of virus during the first eight days of their illness. Scientists found that patients exhale quite a bit of virus during the first several days — as many as 1,000 copies of airborne virus per minute. Those levels drop steeply by day eight, however, when a person exhales only about two copies per minute. “This information speaks directly to when someone with COVID-19 should isolate; when they are more likely to infect other people by breathing out virus into the air around them; and when they become much less likely to spread the infection,” lead study author Gregory Lane, a senior research project manager at Northwestern University Feinberg School of Medicine, in Chicago, said in a university news release. The study’s aim was to figure out “how much virus a patient is exhaling into the environment over the course of their infection and for how long,” study co-author Christina Zelano added in the news release. She’s an assistant professor of neurology at Northwestern. The study authors invented and utilized a portable, non-invasive device to collect breath samples. “The vast majority of research on viral loads over the course of a COVID-19 infection has been based on nasal or…  read on >  read on >

Young people who vape are more likely to experience chronic stress, though it isn’t clear whether it was the stress that brought on the vaping or the vaping that caused the stress, investigators say. “Research is starting to show how vaping affects young people’s physical and mental health,” said Dr. Teresa To, a senior scientist at the Hospital for Sick Children (SickKids) in Toronto. “Our previous research has shown that those who vape are more likely to suffer an asthma attack. In this study we were particularly interested in the relationship between vaping, mental health and quality of life among young people,” To said in a news release from the European Respiratory Society. For the new research, investigators used the data from the Canadian Health Measures Surveys, a national survey that included 905 people between 15 and 30 years of age. About 13% said they had used e-cigarettes. Researchers found that young people who vape were more likely to be physically active but were also more likely to report experiencing extreme chronic stress in their lives. “Chronic stress can lead to mental health conditions such as anxiety and depression. It’s important for young people experiencing chronic stress to be given support early on to help them avoid resorting to unhealthy coping mechanisms like vaping or smoking,” To said. “Vaping is not an effective way to…  read on >  read on >

The U.S. Food and Drug Administration on Monday gave the green light to new COVID boosters for Americans, setting the stage for the updated vaccines to become available within days. The COVID-19 shots from Pfizer and Moderna will join the flu shot and newly approved RSV shots as part of a three-pronged public health strategy to tame the spread of all three viruses this coming winter. The updated COVID vaccines are each fully approved for those 12 and older and are authorized under emergency use for individuals 6 months through 11 years of age. “Vaccination remains critical to public health and continued protection against serious consequences of COVID-19, including hospitalization and death,” Dr. Peter Marks, director of the FDA’s Center for Biologics Evaluation and Research, said in an agency news release. “The public can be assured that these updated vaccines have met the agency’s rigorous scientific standards for safety, effectiveness and manufacturing quality. We very much encourage those who are eligible to consider getting vaccinated.” One infectious diseases expert said the approvals matter most to vulnerable Americans. “Having an updated booster that more closely matches circulating strains is an important tool for high-risk individuals, who still remain at risk for severe disease, hospitalization and death,” said Dr. Amesh Adalja, a senior scholar with Johns Hopkins’ Center for Health Security in Baltimore. Next up? The Advisory…  read on >  read on >

As this summer has shown, the massive smoke plumes generated by wildfires can dirty the air of regions many miles away. Now a new study is raising the question of whether that pollution is contributing to suicides in rural America. Researchers found a correlation between air pollution from “drifting” wildfire smoke and a rise in U.S. counties’ suicide rates. The connection was not seen everywhere, however: It was concentrated in rural counties, and among certain groups with a relatively heightened suicide rate to begin with: white, working-age men without a college education. For every 10% increase in wildfire air pollutants, the study found, a rural county’s monthly suicide rate rose by 1.5%, on average. The study was published Sept. 11 in Proceedings of the National Academy of Sciences. It cannot prove that dirty air is to blame. And experts said it’s unclear exactly what is going on. But the findings add to evidence tying air pollution — and more broadly, climate change — to mental health consequences. Recent studies have linked exposure to heavy air pollution to aggression and increased risks of depression, anxiety and even dementia. And there is some understanding for why “junk in the air” might harm not only physical health, but mental health, too, according to David Molitor, the lead researcher on the new study. Tiny particles in air pollution, including…  read on >  read on >

Could an algorithm take your job someday? Concerns about artificial intelligence, or AI, are plaguing U.S. workers, according to a new American Psychological Association poll. Some workers are uncomfortable with the way their employers are tracking them, while others worry that AI will make their jobs obsolete. “Employers interested in investing in artificial intelligence systems must also invest in their employees, educating them about the role of AI and provide opportunities for feedback,” said Arthur Evans Jr., chief executive officer of APA. “The workplace is changing rapidly. Open and honest communication from employers can help relieve employees’ anxieties about the unknown and improve overall well-being, which is associated with higher organizational performance,” Evans said in an association news release. The APA poll surveyed more than 2,500 employed adults in the second half of April. Nearly 2 in 5 workers polled said they were worried that AI might one day make some or all of their job duties obsolete. About 64% of those who said they were worried about AI also said they felt tense or stressed during the workday, compared to 38% of those who were not worried about AI. Workers with a high school education or less were significantly more likely than those with a four-year college degree to be worried that their jobs would become obsolete — 44% to 34%. About 50% of…  read on >  read on >

Two new studies looked to explain an increased risk of respiratory infections like coughs and colds in babies and young children, finding city living to be among the culprits. Young children who grow up in towns and cities instead of the countryside suffer more respiratory infections, according to research presented Monday at a meeting of the European Respiratory Society, in Milan, Italy. Findings presented at medical meetings are considered preliminary until published in a peer-reviewed journal. A second study that was also presented at the event and published Sept. 11 in the journal Pediatric Pulmonology, found that attending day care, living in a damp home or residing near dense traffic increased young children’s risk of chest infections. That study also noted that breastfeeding reduced the risk. In the first study, researchers included more than 660 children and their mothers. Participation began during pregnancy and continued until the children were 3 years old. By age 3, kids living in urban areas averaged 17 respiratory infections, such as coughs and colds, compared to 15 for kids in rural areas. That research also included detailed blood tests of the pregnant women and their newborns. Researchers analyzed the infants’ immune systems at 4 weeks of age and found differences between the urban and rural babies. There were also differences in blood samples from moms and babies related to living…  read on >  read on >

Babies who have more mature microbes in their gut are less likely to have allergy-related wheezing and asthma in early childhood, according to new research. “Our studies on the Barwon Infant Study showed that a more mature infant gut microbiota at one year of age was associated with a lower chance of developing food allergies and asthma in childhood. This appeared to be driven by the overall composition of the gut microbiota rather than specific bacteria,” said Dr. Yuan Gao, a research fellow at Deakin University in Geelong, Australia. “We then hypothesized that advanced maturation of the infant gut microbiota in early life is associated with decreased risk of allergy-related wheeze in later childhood,” Gao said. Study findings were presented Sunday in Barcelona at a meeting of the European Respiratory Society. The Barwon Infant Study (BIS) has been ongoing in Australia since 2010. More than 1,000 babies were recruited between 2010 and 2013 and researchers have been following them as they grow. They studied the bacteria present in fecal samples collected from the babies at age 1 month, and again at 6 and 12 months. At one- and four-year reviews, parents reported whether their children had developed allergy-related wheeze or asthma during the past year. The team also did skin-prick tests to see if children had allergic reactions to any of 10 foods as well…  read on >  read on >

SATURDAY, Sept. 9, 2023 (HealthDay News) – Lots of parents are giving their children the supplement melatonin to help with sleep, but is it safe? In a new survey, the American Academy of Sleep Medicine (AASM) found that 46% of parents — what it called a “shocking number” — have given melatonin to children under the age of 13. About 30% gave their teenager melatonin to aid in sleep. Yet, there is little evidence that melatonin helps with insomnia in children, the AASM said. A natural hormone that helps regulate the body’s internal clock, melatonin may seem like a simple solution, the AASM said. Yet the organization noted important safety concerns. Parents should talk to a health care professional before giving melatonin or any supplement to children, the AASM advised. Melatonin supplements do not have U.S. Food and Drug Administration oversight in the way over-the-counter or prescription medications do, and the contents can vary widely among products and brands. In one study, researchers found that melatonin ranged from less than one-half to more than four times the amount stated on the label. Chewable tablets had particularly significant variability. Some of the supplements even contained other chemicals that require medical prescriptions. “Because many sleep difficulties children experience can be fixed with behavioral changes, parents should help their child establish consistent bedtime routines and practice good sleep…  read on >  read on >

There’s an adage that in romantic relationships, opposites attract. Now, a large, new study confirms that just like many old sayings, it’s wrong. In an analysis of about 200 studies involving millions of couples, researchers came to the conclusion that there is little behind the claim that opposites attract. If anything, the one about birds of feather flocking together is much closer to the truth. When it came to the hundreds of “traits” the study analyzed — from political leanings to smoking and drinking habits — partners were almost always more alike than different. It was only in relation to 3% of traits that people tended to pair off with someone who had different inclinations, according to the findings published recently in the journal Nature Human Behaviour. To be fair to the adage, the findings do not mean that people rarely find themselves attracted to someone who is much different from them. “We looked at cohabiting and co-parenting couples,” explained lead researcher Tanya Horwitz, a doctoral candidate at the University of Colorado Boulder. “So, this study speaks to long-term relationships.” On average, the findings show, long-term partners are similar in a host of ways — from religious and political beliefs, to educational background and certain aspects of intelligence, to lifestyle habits. The results are based on data from 199 published studies involving millions of male-female…  read on >  read on >

Therapies based on a hormone people make while exercising may be the next frontier in treating Alzheimer’s disease, according to a new study. Researchers have found that the exercise-induced hormone irisin may reduce both the plaque and the tau tangles characteristic of the disease. Before this, this same team developed the first 3D human cell culture models of Alzheimer’s disease, which it was able to use in this new research into the impact of irisin on amyloid beta in the brain. Physical exercise had already been shown to reduce amyloid beta deposits in mouse models of Alzheimer’s, but it wasn’t clear how. The increase of circulating levels of the muscle-derived hormone irisin through exercise regulates glucose and lipid metabolism in fat tissue. It also increases energy expenditure by accelerating the browning of white fat tissue. Past research has shown that irisin is present in human and mouse brains. Its levels are lower in patients with Alzheimer’s. “First, we found that irisin treatment led to a remarkable reduction of amyloid beta pathology,” said study author Se Hoon Choi, of the Genetics and Aging Research Unit at Massachusetts General Hospital in Boston. “Second, we showed this effect of irisin was attributable to increased neprilysin activity owing to increased levels of neprilysin secreted from cells in the brain called astrocytes,” he said in a hospital news release. Neprilysin…  read on >  read on >