The future for a child diagnosed with scoliosis, an abnormal curvature of the spine that typically occurs just before puberty, can feel uncertain. As a parent, you want answers to your questions about scoliosis and how it can affect your child’s development. Here’s what you need to know. What is scoliosis? Scoliosis is an abnormal sideways curvature of the spine. In some cases, the spine curves either to the left or the right in a “C” shape. In others, the spine curves both ways in an “S” formation, according to Boston Children’s Hospital. What causes scoliosis? The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) explains idiopathic scoliosis is the most common type and the cause is unknown; however, a combination of genes, hormones and changes in cell structure could be the cause. Other causes include: Congenital factors occurring during fetal development Genetic disease Traumatic injury Neuromuscular diseases like cerebral palsy Tumors Types of scoliosis “There are three primary types,” said Dr. Stephen George, a pediatric orthopedic surgeon at Nicklaus Children’s Hospital in Miami. George explains in an online video the three types are: congenital; neuromuscular; and the most common, idiopathic scoliosis. Congenital scoliosis is caused by malformed vertebrae during fetal development. Neuromuscular scoliosis is due to weak muscles that are unable to support the spine. This is the result of muscle impairment… read on > read on >
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FDA Approves First Gene Therapy to Treat Duchenne Muscular Dystrophy
The U.S. Food and Drug Administration on Thursday approved the drug Elevidys, the first gene therapy for the treatment of children with Duchenne muscular dystrophy (DMD). The groundbreaking treatment will not be cheap: Drugmaker Sarepta Therapeutics Inc. said it would charge $3.2 million for the one-time IV treatment, the Associated Press reported. Like most medicines in the United States, the cost would be mostly paid by insurers. The drug will be used to treat children ages 4 through 5 who have a mutation in the DMD gene. “Today’s approval addresses an urgent unmet medical need and is an important advancement in the treatment of Duchenne muscular dystrophy, a devastating condition with limited treatment options, that leads to a progressive deterioration of an individual’s health over time,” Dr. Peter Marks, director of the FDA’s Center for Biologics Evaluation and Research, said in an agency news release. “The approval of Elevidys is a watershed moment for the treatment of Duchenne. Elevidys is the first and only gene therapy approved for Duchenne, and this approval brings us closer to our goal of bringing forward a treatment that provides the potential to alter the trajectory of this degenerative disease,” Sarepta President and CEO Doug Ingram said in a company statement. Advocates welcomed the approval. “Today’s decision marks an important moment in gene therapy for patients living with Duchenne,” said… read on > read on >
What’s Really Killing the ‘Night Owls’?
It’s not the late nights, but the smoking and drinking that happen during those late nights, that are killing people who are “night owls” earlier in life, a new study claims. Researchers studied twins in Finland for 37 years, looking at different chronotypes, the body’s natural inclination to sleep at a certain time. Although they saw that the evening types had a slightly increased risk of dying than the morning types, it was those other habits that were at the root of that greater likelihood of premature death, the study found. The findings were published June 15 in the journal Chronobiology International. “Our findings suggest that there is little or no independent contribution of chronotype to mortality,” said study author Dr. Christer Hublin, from the Finnish Institute of Occupational Health in Helsinki. “In addition, the increased risk of mortality associated with being a clearly ‘evening’ person appears to be mainly accounted for by a larger consumption of tobacco and alcohol,” Hublin said in a journal news release. “This is compared to those who are clearly ‘morning’ persons.” Researchers were inspired to do this study by past studies that had linked night owls to a higher risk of disease, including heart problems. Among those were data from the UK Biobank published as part of a 2018 study that found a small increased risk of death from… read on > read on >
Upper Back Pain: Causes and How to Treat It
If you suffer from upper back pain, it’s time to reclaim your comfort and regain control of your daily life. Relief from this debilitating condition is within reach. Here, you will learn about the causes of upper back pain and strategies to alleviate your discomfort. What is upper back pain? Imagine discomfort that takes residence between your shoulder blades, affecting your daily life, and keeping you from doing many of the things you love. That’s just what upper back pain entails — a sensation of pain or discomfort from the base of your neck to the bottom of your ribcage. According to Dignity Health, this form of back pain can vary in intensity, ranging from a mild annoyance to a debilitating ache, and it can either be persistent or surface only during certain activities. While back pain is widespread, upper left back pain and upper right back pain are less common than their counterparts in the lower back. The bones in your upper and middle back form a sturdy connection with your ribcage, limiting their mobility compared to the more flexible bones in your neck and lower back. This unique skeletal structure contributes to the distinctive nature of upper back pain, requiring specific attention and care. What is causing my upper back pain? If you are experiencing upper back pain, you want to understand what… read on > read on >
Danger Afoot: U.S. Pedestrian Deaths at Highest Level in 41 Years
More than 7,500 people were killed last year after being struck by vehicles while walking along or across U.S. roadways — the most pedestrian deaths in more than four decades, according to a new report. This sobering trend was not surprising to experts who track the numbers. But they were dismayed by the consistent increase — up 77% since 2010. “This is unacceptable. It’s really mind-boggling. It hard to wrap your head around, at least it’s hard for me to wrap my head, 20 deaths every single day,” said Adam Snider, a spokesman for the Governors Highway Safety Association (GHSA), which reported state-by-state numbers this week. “And then when you think about how many people each single death affects: family members, neighbors, friends, mentors, pastors, how many other people we touch in our daily lives,” Snider said. “To think of all those ripple effects, I’m sometimes at a loss for words, just with how unfortunate and awful the situation is.” While pedestrian deaths have been rising sharply over the past dozen years, other traffic-related deaths also increased but at a lower 25%. GHSA used data from state highway safety offices in 49 states and Washington, D.C., for its report. Oklahoma did not provide state data, but has averaged 92 deaths annually in recent years. The projected 7,508 pedestrian deaths nationwide last year was up 1%… read on > read on >
Tough-to-Diagnose Hip Condition Caused Her ‘Excruciating Pain’ Until She Got a New Type of Surgery
New York-based physical therapist Brittany Garrett, now 33, was sidelined by excruciating hip pain for close to eight years before she got an accurate diagnosis and effective treatment. She tried physical therapy to improve her flexibility, among other treatments, but nothing seemed to help. The former volleyball player’s pain was so intense that it was getting in the way of her career and her active lifestyle. “I have to be able to demonstrate exercises, do lunges, be on my feet, get on and off the floor and lift heavy things, and I couldn’t,” Garrett recalled. She eventually underwent imaging exams, including an MRI that showed she had femoroacetabular impingement (FAI), an underdiagnosed condition that occurs when abnormal growths at the hip joint cause painful friction and set the stage for hip osteoarthritis, the wear-and-tear form of the disease. “It was a relief to have the diagnosis and know that it was an anatomical issue, and there was also relief in knowing that I could have surgery to get rid of pain and get my life back,” Garrett said. In the past, this type of surgery involved huge incisions and dislocating the hip, but now some surgeons can treat FAI with minimally invasive hip surgery via tiny incisions and instruments guided by a small camera, reducing risks and downtime. Garrett underwent two minimally invasive surgeries to… read on > read on >
You’ve Suffered Whiplash: Know the Symptoms & Treatments
Whiplash — an often underestimated injury that can strike in the aftermath of a collision — inflicts injury and pain on its unsuspecting victims. If you find yourself grappling with the relentless effects of whiplash, you’re not alone. Numerous legal websites estimate that at least 3 million Americans per year sustain whiplash injuries. Here’s what you should know about a whiplash injury, including what it is, and its causes, symptoms and treatments. What is whiplash? “Whiplash is a type of neck injury that occurs when an individual’s head is jerked backward and then forward suddenly, similar to the cracking of a whip. It commonly happens during motor vehicle accidents, particularly rear-end collisions, but it can also occur during sports activities or falls,” said Dr. Jeremy Smith, an orthopedic spine surgeon and director of the spine surgery fellowship at Hoag Orthopedic Institute in Southern California. The unfortunate truth is that whiplash neck is no joke. The Cleveland Clinic indicates that whiplash is often dismissed as fleeting pain, soreness or stiffness. However, the ramifications can be far-reaching, leading to long-term pain and complications. In the most extreme cases, whiplash has the potential to unleash severe spinal injuries, causing permanent disability or even proving fatal. What causes a whiplash injury? “The primary cause of whiplash injury is the sudden and forceful movement of the head and neck,” Smith… read on > read on >
Head Injury Outcomes Could Take Years to Unfold
A traumatic brain injury (TBI) can have long-term effects, much like a chronic condition, a new study says. Looking at hundreds of patients, researchers found that problems related to traumatic brain injuries can last for years, with people improving and declining at different time points. These problems encompassed memory, thinking and everyday functioning. “TBI is essentially a chronic condition like many other chronic conditions,” said lead researcher Benjamin Brett, an assistant professor in the Departments of Neurosurgery and Neurology at the Medical College of Wisconsin. “Things can change, both up and down, improve and decline throughout multiple years.” Because of this, there’s a need to monitor patients “well beyond that post-injury period,” Brett said. “We need to establish systems of care that involve continued monitoring and treatment.” The idea may be controversial, however. A chronic condition implies an underlying disease that is expected to change and/or get worse in predictable ways, said Dr. Daniel Torres, a neurologist at Northwell Lenox Hill Hospital in New York City. “I would not consider TBI a chronic condition because it is an unpredictable condition with which different individuals can have greatly different consequences,” Torres said. For the study, Brett and his colleagues collected data on more than 900 people who had mild TBIs, mostly concussions, and nearly 200 people who had moderate to severe TBI. These were conditions like… read on > read on >
First Chicken Meat Grown in Labs Gets U.S. Approval
(HealthDay News) – Americans could soon be eating “lab-grown” chicken at upscale restaurants after the U.S. Department of Agriculture approved products made by two companies on Wednesday. Upside Foods and Good Meat, both based in California, will be the first in the United States to sell meat that’s cultivated in a laboratory rather than from slaughtered animals. The meat is still actually meat, coming from animal cells, fertilized eggs or stored cells. “Instead of all of that land and all of that water that’s used to feed all of these animals that are slaughtered, we can do it in a different way,” Josh Tetrick, co-founder and chief executive of Eat Just, which operates Good Meat, told the Associated Press. The U.S. Food and Drug Administration had already determined the products were safe to eat, the AP reported. Manufacturing company Joinn Biologics was given the go-ahead to make products, which will initially be sold at the restaurant Bar Crenn in San Francisco in the case of Upside products, and at restaurant in Washington, D.C., run by chef Jose Andrés in the case of Good Meat. Singapore was the first country to begin allowing cultivated meat, the AP reported. The meat is grown in steel tanks, coming out in large sheets and then cut into expected shapes. The Upside chicken looks slightly paler, but has the same… read on > read on >
Diet Heavy in Omega-3s Might Help Slow ALS
Consuming omega-3 fatty acids like flaxseed oil and walnuts may help slow the decline in physical function related to amyotrophic lateral sclerosis (ALS), new research suggests. ALS (formerly known as Lou Gehrig’s disease) is a progressive neurodegenerative disease that affects nerve cells in the brain and spinal cord. People with ALS lose the ability to initiate and control muscle movement over time. The average life span after diagnosis is two to five years. A slower decline in symptoms may also slightly extend survival for people with ALS, the researchers noted. The new study findings were published online June 21 in the journal Neurology. “The link our study found between diet and ALS is intriguing and suggests, but does not prove, that people with ALS may benefit from incorporating more omega-3 fatty acids into their diet,” said Dr. Kjetil Bjornevik, an assistant professor of epidemiology and nutrition at Harvard T.H. Chan School of Public Health, in Boston. “It will now be important to conduct additional research looking specifically at the plant-based omega-3 fatty acid alpha-linolenic acid in people with ALS to further explore this possibility,” Bjornevik said in a journal news release. Besides flaxseed oil and walnuts, good sources of omega-3 fatty acids include canola oil and pumpkin seeds. Consuming more omega-6 fatty acid could also be beneficial, the investigators found. To study the link between… read on > read on >