Considered one of the most common sexually transmitted diseases, chlamydia can spread easily and often without obvious symptoms. And although chlamydia cases have declined in recent years, the U.S. Centers for Disease Control and Prevention chalks that up to reduced screening for sexually transmitted diseases (STDs) during the pandemic. It is estimated that 1 in 20 sexually active women between the ages of 14 and 24 gets chlamydia, according to the American Sexual Health Association (ASHA). The side effects of untreated infection are significant, per the CDC: Chlamydia can permanently damage a woman’s reproductive system, and can also cause a potentially fatal ectopic pregnancy (one that occurs outside the womb). What is chlamydia? Chlamydia is a bacterial infection that can be treated effectively if caught early, according to the Mayo Clinic. Often, it is symptom-free, making it easy to spread before someone realizes they have it. Between 50% and 70% of those who catch it don’t know they’ve caught it — a fact that has earned chlamydia the nickname of the “silent infection.” Research published recently in the Journal of Adolescent Health found that an opportune time to screen young women for chlamydia would be when they get long-acting birth control from their doctors. Is chlamydia curable? Because it is a bacterial infection, chlamydia is curable with antibiotics when caught early, according to the Cleveland…  read on >  read on >

A gene-editing experiment that restored the vision of mice might one day be used to treat a major cause of human blindness. Scientists in China reported they used the CRISPR-based gene-editing technique to bring back vision in mice with retinitis pigmentosa. Genome editing has previously been used to restore the vision of mice with genetic diseases such as Leber congenital amaurosis, which affect a layer of cells in the eye that supports the light-sensing rod and cone photoreceptor cells. Most of these conditions are caused by genetic defects in the photoreceptors themselves. “The ability to edit the genome of neural retinal cells, particularly unhealthy or dying photoreceptors, would provide much more convincing evidence for the potential applications of these genome-editing tools in treating diseases such as retinitis pigmentosa,” said researcher Kai Yao, a professor at Wuhan University of Science and Technology. For the study, Yao’s team set out to restore the vision of mice with retinitis pigmentosa caused by a flaw in a gene encoding a critical enzyme called PDE6B. For the task, they developed a more versatile CRISPR system called PESpRY. It can be programmed to correct many types of genetic mutation, no matter where they occur within the genome. When programmed to target the mutant gene, PESpRY efficiently corrected the mutation, according to the study. It restored the enzyme’s activity in the retinas…  read on >  read on >

Many patients worry that receiving a metal implant might set off their metal allergy, according to the American Academy of Dermatology. “Cases in which patients are inquiring about a metal allergy as it relates to their metal implants — including joint replacements, rods, pins, screws, plates, certain neurologic and cardiac devices such as pacemakers, and dental devices — are becoming more prevalent as medical implants become more common,” said Dr. Golara Honari, a clinical associate professor of dermatology at Stanford School of Medicine. About 10% of Americans will receive a medical implant during their lifetime. Millions of people in the United States report having a metal allergy. Metal, especially nickel, is one of the most common causes of allergic contact dermatitis, Honari said. It develops when skin is exposed to an allergen, often leading to a rash and itching. Other symptoms can include dryness, hives, blisters or pain. Honari noted that suspected metal implant allergies can be difficult to diagnose because everyone’s immune system reacts to allergens differently. Close collaboration between a dermatologist and the surgeon or physician who placed the implant is essential, she said. Patients who need an implant and have a documented history of a metal allergy should notify their dermatologist and physician or surgeon about any allergies prior to the procedure. Alternatives to metal implants are available. “For example, if it’s…  read on >  read on >

Commonly known as the “clap,” gonorrhea is a sexually transmitted disease that can cause infertility in both women and men if left untreated. The bad news is that cases are on the rise: According to the U.S. Centers for Disease Control and Prevention, some sexually transmitted diseases (STDs) are on a steady and steep climb. Gonorrhea, already the second most common STD in the United States, saw a 10% increase in prevalence in 2020 alone. “The COVID-19 pandemic put enormous pressure on an already strained public health infrastructure,” Dr. Jonathan Mermin, director of CDC’s National Center for HIV, Viral Hepatitis, STD, and TB Prevention, said recently. “There were moments in 2020 when it felt like the world was standing still, but STDs weren’t. The unrelenting momentum of the STD epidemic continued even as STD prevention services were disrupted.” The even worse news is that gonorrhea has developed antibiotic resistance, with recent research showing the bacteria is now resistant to numerous antibiotics in many parts of Africa. Doctors are down to one last effective class of antibiotics, cephalosporins, to treat a gonorrhea infection. What is gonorrhea? Gonorrhea is a bacteria that is spread through sexual contact, and sometimes through childbirth. The Mayo Clinic reports it most commonly affects the genitals, rectum and throat. In babies born to infected moms, it most commonly presents as an eye…  read on >  read on >