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Single Dose of Psychedelic Curbs Depression, But Study Raises Concerns

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A single psychedelic trip with psilocybin — the mind-altering component of magic mushrooms — appears to lift the fog of major depression in some hard-to-treat patients, a new clinical trial reports. A 25-milligram dose of a synthetic psilocybin compound called COMP360 caused a “rapid and durable response” in more than a third of patients suffering from treatment-resistant depression, said Dr. Steve Levine, senior vice president of patient access for the London-based pharmaceutical company COMPASS Pathways. It focuses on psilocybin research and created the COMP360 synthetic compound and funded the clinical trial. The results occurred in a phase 2 trial aimed at finding the most effective dose of COMP360, according to a report published Nov. 3 in the New England Journal of Medicine. However, there was one caveat: While side effects were minimal, four patients (out of 79) who took the highest dose either reported having suicidal thoughts or intentionally harming themselves in the weeks that followed. The psilocybin compound will now proceed to a full-fledged clinical trial that promises to be the largest ever conducted for a psychedelic compound, Levine said. The trial testing its effectiveness is expected to include more than 900 people in 14 countries, including the United States, Levine said. It’s expected to conclude in mid-2025. These early findings show that psilocybin could well provide an alternative to standard treatments for major…  read on >  read on >

‘First Impression’ Factors That Matter When Dating Turns to Love

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When it comes to love, first impressions matter. But what exactly fuels the flames of romance? It turns out that compatibility and popularity are two of the key factors shaping who people pursue as potential partners, a new speed-dating study suggests. “Although we expected that compatibility would be an important factor, we were amazed to find that compatibility was just as strong of a predictor of romantic pursuit as popularity was,” said study author Alexander Baxter, a PhD candidate in the psychology department at the University of California, Davis. For the study, researchers analyzed romantic first impressions among more than 550 speed-daters, including some men who date men, to rate their romantic interest in potential partners. There were more than 6,600 speed-dates in total during the experiment. The research team looked at three factors that affect how romantic first impressions form: selectivity, popularity and compatibility. “If Daniel liked Rose because he tended to like everyone, this would be selectivity,” Baxter explained. “If Daniel liked Rose because everyone liked her, this would be popularity, and if Daniel uniquely liked Rose above and beyond his own flirty disposition and her general popularity, this would be compatibility.” After the speed-dating events, the researchers asked folks if they dated anyone they met and how their feelings changed over the next two to three months. They used a statistical model…  read on >  read on >

Whole Wheat Better for You Than White Bread, Study Confirms

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New research reinforces advice to include more whole grains in your diet. A diet heavy in “refined” grains (such as white bread, cookies and muffins) may increase your risk for heart disease and early death, while whole grains may lower it, according to the study. “We encourage people to have moderate consumption of carbohydrates and to have different types of grain, especially whole grain,” said lead researcher Mahshid Dehghan, of the Population Health Research Institute at McMaster University in Hamilton, Ontario, Canada. “Reduction in quantity and improving the quality of carbohydrates is the message of our study,” Dehghan said. Grains like oats, rice, barley and wheat make up about half of diets around the world and as much as 70% in low- and middle-income countries, particularly in Africa and South Asia, the researchers noted. The findings don’t prove that a diet heavy in refined grains causes stroke, heart attacks or other forms of heart disease, only that there seems to be a link. For the study, the research team collected data on more than 137,000 people in 21 countries who were aged 35 to 70, had no history of heart disease and were tracked for more than nine years. People who reported eating 12 ounces of refined grains a day were found to have 27% higher odds of early death and a 33% higher risk…  read on >  read on >

Study Shows Young COVID Survivors Can Get Reinfected

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THURSDAY, Feb. 4, 2020 (HealthDay) — Being infected with the virus that causes COVID-19 is not a foolproof shield against reinfection, a small preliminary study warns. The finding stems from tracking nearly 3,250 young U.S. Marine recruits between May and October. Of those, 189 had previously tested positive for the SAR-CoV-2 virus. During the six-week study itself, 10% of those who had tested positive got reinfected. “You don’t have a get-out-of-jail-free card just because you have antibodies from a previous infection,” said study author Dr. Stuart Sealfon. He’s a professor of neurology at Icahn School of Medicine at Mount Sinai in New York City, which conducted the study in collaboration with the Naval Medical Research Center. The findings were recently published in the preprint server medRXiv and have not been peer-reviewed. All the Marines were beginning basic training and were initially held in Navy quarantine for two weeks, after two weeks of at-home quarantine, according to the study. Once training began, recruits were tested for COVID-19 every two weeks over a six-week period. The result: 19 of the 189 recruits who already had COVID tested positive for a second infection during the study. Researchers said first- and second- infections involved the same strain of the SARS-CoV-2 virus and none involved the new, more transmissible U.K., South African or Brazilian strains that have raised alarm in…  read on >  read on >

Major Medical Groups Urge Americans to Get COVID Vaccine

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Want to live like you did in the carefree days before the pandemic? Just roll up your sleeve when your turn comes to get the COVID-19 vaccine, three major medical groups urge in a new public service campaign. The vaccines are safe, effective and will help end the pandemic, according to the American Hospital Association, American Medical Association and American Nurses Association. “To defeat COVID-19 and get back the moments with friends and family we all miss, we need as many shots in arms as possible,” said Rick Pollack, president and CEO of the hospital association. “It’s imperative that all Americans consider the health of their loved ones and make the decision to take the COVID-19 vaccine when it is their turn,” Pollack said in a joint association news release. Dr. Susan Bailey, president of the American Medical Association, agreed, calling on Americans to exercise civic responsibility. “Whether enough people get the COVID-19 vaccine decides our future and the future toll of the virus, so be ready to do your part,” Bailey said. What if you have concerns in the meantime? Ernest Grant, president of the American Nurses Association, suggested reaching out to a nurse, doctor or other health care professional to get your questions answered. “Try to connect with someone you know and trust who has received a COVID-19 vaccine and ask them about…  read on >  read on >

Cancer Plagues California Sea Lions, With Implications for Humans

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A virus-linked cancer killing California sea lions is sounding a chilling alarm for mankind. Exposure to environmental toxins significantly boosts risk for the herpes-like cancer, which was discovered in sea lions in 1979. Since then, between 18% and 23% of adult sea lions admitted to a California animal rescue-and-research center have died of the disease. That’s the highest rate for a single type of cancer in any mammal, including humans, the researchers said. “The decades of research looking into this deadly disease clearly shows the ocean environment we all share is in trouble, and that we need to find solutions to protect our collective health,” said study co-author Pádraig Duignan, chief pathologist at The Marine Mammal Center in Sausalito, Calif. The study — based on more than 20 years of research and examination of nearly 400 California sea lions — was recently published in the journal Frontiers in Marine Science. The researchers said more must be done to stop ecosystem pollution in order to prevent virus-caused cancer in both wildlife and humans. The study found that the blubber of California sea lions has among the highest levels of some organic pollutants found in any marine mammal. “Even though some of the pollutants we’re finding in the blubber have been out of use for years, these cancer-causing elements remain in the environment for a very long…  read on >  read on >

Study Shows Young COVID Survivors Can Get Reinfected

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THURSDAY, Feb. 4, 2020 (HealthDay) — Being infected with the virus that causes COVID-19 is not a foolproof shield against reinfection, a small preliminary study warns. The finding stems from tracking nearly 3,250 young U.S. Marine recruits between May and October. Of those, 189 had previously tested positive for the SAR-CoV-2 virus. During the six-week study itself, 10% of those who had tested positive got reinfected. “You don’t have a get-out-of-jail-free card just because you have antibodies from a previous infection,” said study author Dr. Stuart Sealfon. He’s a professor of neurology at Icahn School of Medicine at Mount Sinai in New York City, which conducted the study in collaboration with the Naval Medical Research Center. The findings were recently published in the preprint server medRXiv and have not been peer-reviewed. All the Marines were beginning basic training and were initially held in Navy quarantine for two weeks, after two weeks of at-home quarantine, according to the study. Once training began, recruits were tested for COVID-19 every two weeks over a six-week period. The result: 19 of the 189 recruits who already had COVID tested positive for a second infection during the study. Researchers said first- and second- infections involved the same strain of the SARS-CoV-2 virus and none involved the new, more transmissible U.K., South African or Brazilian strains that have raised alarm in…  read on >  read on >

Major Medical Groups Urge Americans to Get COVID Vaccine

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Want to live like you did in the carefree days before the pandemic? Just roll up your sleeve when your turn comes to get the COVID-19 vaccine, three major medical groups urge in a new public service campaign. The vaccines are safe, effective and will help end the pandemic, according to the American Hospital Association, American Medical Association and American Nurses Association. “To defeat COVID-19 and get back the moments with friends and family we all miss, we need as many shots in arms as possible,” said Rick Pollack, president and CEO of the hospital association. “It’s imperative that all Americans consider the health of their loved ones and make the decision to take the COVID-19 vaccine when it is their turn,” Pollack said in a joint association news release. Dr. Susan Bailey, president of the American Medical Association, agreed, calling on Americans to exercise civic responsibility. “Whether enough people get the COVID-19 vaccine decides our future and the future toll of the virus, so be ready to do your part,” Bailey said. What if you have concerns in the meantime? Ernest Grant, president of the American Nurses Association, suggested reaching out to a nurse, doctor or other health care professional to get your questions answered. “Try to connect with someone you know and trust who has received a COVID-19 vaccine and ask them about…  read on >  read on >

Cancer Plagues California Sea Lions, With Implications for Humans

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A virus-linked cancer killing California sea lions is sounding a chilling alarm for mankind. Exposure to environmental toxins significantly boosts risk for the herpes-like cancer, which was discovered in sea lions in 1979. Since then, between 18% and 23% of adult sea lions admitted to a California animal rescue-and-research center have died of the disease. That’s the highest rate for a single type of cancer in any mammal, including humans, the researchers said. “The decades of research looking into this deadly disease clearly shows the ocean environment we all share is in trouble, and that we need to find solutions to protect our collective health,” said study co-author Pádraig Duignan, chief pathologist at The Marine Mammal Center in Sausalito, Calif. The study — based on more than 20 years of research and examination of nearly 400 California sea lions — was recently published in the journal Frontiers in Marine Science. The researchers said more must be done to stop ecosystem pollution in order to prevent virus-caused cancer in both wildlife and humans. The study found that the blubber of California sea lions has among the highest levels of some organic pollutants found in any marine mammal. “Even though some of the pollutants we’re finding in the blubber have been out of use for years, these cancer-causing elements remain in the environment for a very long…  read on >  read on >

Study Shows Young COVID Survivors Can Get Reinfected

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THURSDAY, Feb. 4, 2020 (HealthDay) — Being infected with the virus that causes COVID-19 is not a foolproof shield against reinfection, a small preliminary study warns. The finding stems from tracking nearly 3,250 young U.S. Marine recruits between May and October. Of those, 189 had previously tested positive for the SAR-CoV-2 virus. During the six-week study itself, 10% of those who had tested positive got reinfected. “You don’t have a get-out-of-jail-free card just because you have antibodies from a previous infection,” said study author Dr. Stuart Sealfon. He’s a professor of neurology at Icahn School of Medicine at Mount Sinai in New York City, which conducted the study in collaboration with the Naval Medical Research Center. The findings were recently published in the preprint server medRXiv and have not been peer-reviewed. All the Marines were beginning basic training and were initially held in Navy quarantine for two weeks, after two weeks of at-home quarantine, according to the study. Once training began, recruits were tested for COVID-19 every two weeks over a six-week period. The result: 19 of the 189 recruits who already had COVID tested positive for a second infection during the study. Researchers said first- and second- infections involved the same strain of the SARS-CoV-2 virus and none involved the new, more transmissible U.K., South African or Brazilian strains that have raised alarm in…  read on >  read on >