All Sauce from Weekly Gravy:

Some menstrual products — pads, tampons, cups and underwear — contain harmful “forever chemicals,” according to new research into the contents of these essential items. Researchers analyzed more than 100 period products looking for fluorinated compounds, an indicator of potentially harmful per- and polyfluoroalkyl substances, or PFAS. The products typically don’t list ingredients on their packaging. PFAS include more than 12,000 compounds that can resist water, stains and sticking. They don’t break down easily in the environment or the human body, but instead accumulate. While exposure to these compounds has been linked to some cancers and immune suppression, there are few regulatory limits on PFAS or period products in the United States or Europe. Researchers presented their findings Sunday at a meeting of the American Chemical Society, in San Francisco. “Of course, you’re concerned for the wearer, but we’re also concerned about the ecological impact because PFAS are ‘forever chemicals,’” said principal investigator Graham Peaslee, a professor of physics at the University of Notre Dame. “Once these products are thrown away, they go to landfills and decay, releasing PFAS into groundwater,” he said in a meeting news release. “And we, or later generations, could end up inadvertently ingesting them.” How much PFAS can pass from materials to skin is unknown. For this study, researchers analyzed a variety of period products, from single-use to reusable products.…  read on >  read on >

If you’re moving into a home where smokers lived, the first thing you should do to protect your lungs is rip out any old carpeting, new research suggests. Scientists found that tobacco smoke clings to carpet fibers long after smoking has stopped, and ozone generators that purify the air and surfaces can’t remove it completely. This leftover residue, also known as “thirdhand smoke,” can pollute indoor spaces for an extended period of time, according to investigators from the U.S. Department of Energy’s Lawrence Berkeley National Laboratory in Berkeley, Calif. “Because it does not reach deeply into materials, ozone [purification] has a limited ability to ‘clean’ permanently,” study lead author and researcher Xiaochen Tang said in a lab news release. “In the case of carpet, the best solution may be replacing it with a new one.” This thirdhand smoke reenters the air, rather than just settling into surfaces, and can sometimes transform into a new type of contaminant, the research found. To study this, researchers gathered old smoke-contaminated carpet from homes in the San Diego area, along with new carpet exposed to fresh smoke in the lab. Ozone generators partially removed a group of compounds named polycyclic aromatic hydrocarbons from both types of carpet samples. However, it was relatively ineffective at removing deeply embedded nicotine. Ozone generators work by releasing ozone gas that can react with…  read on >  read on >

Heading back to school requires supplies and planning for all, but if you’re a parent of a child with allergies or asthma then you have even more to consider. “The start of a new school year is exciting for some, but for parents of children with allergies and asthma, their thoughts are probably on keeping their child free from triggers that can cause allergic reactions,” said allergist Dr. Kathleen May, president of the American College of Allergy, Asthma and Immunology (ACAAI). “Allergies and asthma can significantly impact a child’s well-being and academic performance, but with proper preparation and management, they can thrive in the school environment,” May said in an ACAAI news release. ACAAI offers four tips to help parents get their child off to a smart start to the school year. Identify allergy triggers: Find out what’s causing your child’s allergic symptoms, such as pollen, mold, dust mites, pet dander or certain foods. Work with your child’s allergist to make sure you have the right treatments in place, including getting the proper prescriptions for their weight and age. Share your action plan: Your child’s management plan should outline symptoms, medications, emergency contacts and what to do in the event of flare-ups. Be sure the school nurse, teachers and other staff are familiar with the plan and are prepared to respond effectively in case of…  read on >  read on >

The link between pro football and the risk for a neurodegenerative disease called chronic traumatic encephalopathy (CTE) is well known, and now a new study suggests that football may also up the risk for Parkinson’s disease, even among past high school and college players. “Parkinson’s disease has been commonly reported in boxers, but we have not explored this link in great detail in football,” said study author Michael Alosco, an associate professor of neurology at Boston University Chobanian & Avedisian School of Medicine. “This is additional evidence that shows a link between football and later-in-life neurologic problems.” The common denominator is likely blows to the head. Parkinsonism is an umbrella term for a group of neurological disorders that result in movement problems. Parkinson’s disease is the most common cause. Symptoms include tremors, stiffness, a shuffling gait and slow movement. Exactly what causes Parkinson’s disease is not fully understood, but a combination of genetic and environmental factors likely play a role, according to the Michael J. Fox Foundation for Parkinson’s Research. For the study, researchers evaluated 1,875 athletes, including 729 men who played football, predominantly at the amateur level, and 1,146 men who played other sports. All of the participants were enrolled in Fox Insight, an online study of people with and without Parkinson’s disease sponsored by the Michael J. Fox Foundation. Participants who did not…  read on >  read on >

A single hardwired brain circuit might be responsible for male sexual drive, a new mouse study reports. Researchers have singled out in lab mice a brain region that controls sexual interest, libido, mating behavior and pleasure, said senior researcher Dr. Nirao Shah, a professor of psychiatry and neurobiology at Stanford University School of Medicine, in California. This region uses sensory input from the environment to recognize the sex of another mouse — “Aha, this is a female, maybe I can mate if she’s willing,” Shah said. “That recognition is then transformed into the desire to mate and the act of mating by this circuit,” he added. “Also, the circuit enables the behavior to be pleasurable so animals will seek to do it again, which is very important, because for a species to survive, animals need to reproduce.” While this study was in mice, Shah said similar brain structures have been found in other mammals — and perhaps even humans. “There are analogous anatomical counterparts we think in the human brain, but of course their function in the human brain remains to be determined,” he noted. For their experiments, Shah’s team used adult virgin male mice that had not seen a female mouse after being weaned at about 3 weeks of age. That way, the brain activity and behavior they observed would not have been shaped…  read on >  read on >

FRIDAY, Aug. 11, 2023 (HealthDay News) – As demand for the wildly popular weight-loss drug Wegovy continues to climb, drug maker Novo Nordisk said Thursday that it will continue restrictions on starter doses of the medication into 2024. The new plan extends by months existing restrictions and means patients who are not already taking the medication will have to wait to start. “We are going to continue to supply the market, but it’s just going to be on a limited form so we can have that continuity of care,” Doug Langa, executive vice president of North America Operations for Novo Nordisk, told CNN. “We’re still producing all strengths and we’re still supplying all strengths to the market,” Langa said. The company had previously expected the restriction to last through September. Eli Lilly is also struggling with supply and demand issues for its type 2 diabetes medication Mounjaro. That medication does not yet have U.S. Food and Drug Administration approval as a weight-loss drug. “Supply will likely remain tight in the coming months and quarters due to significant demand,” Eli Lilly Chief Financial Officer Anat Ashkenazi told CNN. Mounjaro targets a hormone known as GLP-1 and another called GIP, while Wegovy is a GLP-1 agonist, using semaglutide as its key ingredient. Novo Nordisk’s diabetes drug Ozempic also uses semaglutide, but in a smaller dose. Prescriptions for…  read on >  read on >

The mental health crisis hitting Americans shows no sign of abating, with provisional numbers for 2022 showing suicides rose by another 2.6% last year. That follows on an overall 5% increase in suicides in 2021, noted officials at the U.S. Centers for Disease Control and Prevention, which on Thursday released the early data for 2022. Overall, 49,449 Americans lost their lives to suicide last year, up from 48,183 deaths in 2021, the agency reported. “Today’s report underscores the depths of the devastating mental health crisis in America,” U.S. Surgeon General Dr. Vivek Murthy said in a CDC news release. “Mental health has become the defining public health and societal challenge of our time. Far too many people and their families are suffering and feeling alone.” The ongoing rise in mental health issues spurred the launch a year ago of the 988 Suicide and Crisis Lifeline, which is available 24/7 to anyone who feels they are in crisis. According to the latest CDC data, there was one glimmer of hope in the new statistics: An 8.4% drop in 2022 for suicides among the very young (ages 10 to 24), and a 6.1% drop among one group hit particularly hard by mental health issues and suicide, American Indian/Alaska Native people. Still, most demographics saw a rise in suicide rates. “The troubling increase in suicides requires immediate action…  read on >  read on >

People with autism are over three times more likely than their peers without the developmental disorder to experience self-injury, suicidal ideation, suicide attempt, or death by suicide, new research shows. “In general, I think there needs to be more support for individuals with autism. And this shows that there are life-threatening consequences in terms of suicide and self-harm,” said Alycia Halladay, chief science officer for the Autism Science Foundation. She was not involved in the study. The researchers agreed. “The presence of psychiatric illnesses substantially accounts for these increased risks,” said lead study author Dr. Meng-Chuan Lai, staff psychiatrist and clinician scientist with the Child and Youth Mental Health Collaborative at the Centre for Addiction and Mental Health (CAMH) at the University of Toronto. “We know that many self-harm and suicide-related events could be prevented when people have access to tailored mental health supports and services, and this is crucial for autistic people,” he said in a CAMH news release. Megan Pilatzke is an advocate and a woman living with autism. ”Autistic people are continually forced to mask and hide who we are to accommodate a world that generally does not accept our traits,” Pilatzke said in the release. “I want people to understand that autistic people are struggling because our needs are just not being met throughout society.” Broken down by gender, females with…  read on >  read on >

Modern antidepressants could be effective for long-term treatment of some patients with bipolar disorder, a new trial suggests. Current guidelines discourage use of antidepressants in these patients, over concerns that the drugs will trigger a manic episode. But bipolar patients who remained on antidepressants for a whole year had fewer mood episodes than those who were switched to a placebo after two months, the investigators found. These results “should change practice and it should convert more people that were nonbelievers to saying, yeah, at least for some patients, continuing antidepressants is a good strategy,” said lead researcher Dr. Lakshmi Yatham, head of psychiatry at the University of British Columbia, in Canada. However, the clinical trial doesn’t provide cut-and-dried support for antidepressants. The trial failed its primary goal of showing a statistically significant benefit for using antidepressants long-term versus short-term, because too few patients participated, noted Dr. Michael Thase, a psychiatrist with Penn Medicine in Philadelphia. “You have an effect on the main primary outcome that is in the direction of a clinically meaningful effect in favor of staying on the antidepressants, but it’s below the threshold of statistical significance because the study didn’t get to the size that it was supposed to be,” explained Thase, who was not part of the research. Depressive episodes are of great concern to doctors because they bring with them…  read on >  read on >

Microplastics appear to be everywhere, including within the tissues of the human heart. A new Chinese report describes doctors finding microplastics in heart tissue both before and after heart surgery. The researchers also noted there is evidence suggesting that microplastics may have been unexpectedly introduced during the heart procedures. The researchers, who included Kun Hua and Xiubin Yang from Capital Medical University in Beijing, collected heart tissue samples from 15 people during cardiac surgeries. They also gathered blood samples from the patients both before and after surgery. These plastic fragments, about the size of a pencil eraser or smaller, can enter the human body through mouths, noses and other body cavities. The full extent of microplastics inside the body isn’t known because most organs and tissues are fully enclosed within the body. In this study, the team analyzed the samples with laser direct infrared imaging, identifying 20- to 500-micrometer-wide particles made from eight types of plastic. These included polyethylene terephthalate, polyvinyl chloride and poly(methyl methacrylate). Most tissue samples had tens of thousands of individual microplastic pieces. The blood samples also contained plastic particles. However, the average size of those particles decreased after surgery. The findings were reported recently in the American Chemical Society’s Environmental Science & Technology journal. The study was small but provides preliminary evidence that microplastics can accumulate and persist in the heart.…  read on >  read on >