All Sauce from Weekly Gravy:

A new analysis shows that parts of the country that had been spared the worst of the coronavirus pandemic are now tallying record-high cases of new infections. Since the start of June, 14 states and Puerto Rico have recorded their highest seven-day average of new coronavirus cases since the pandemic began, data tracked by the Washington Post shows: Alaska, Arizona, Arkansas, California, Florida, Kentucky, New Mexico, North Carolina, Mississippi, Oregon, South Carolina, Tennessee, Texas and Utah. At the same time, new predictions from the University of Washington in Seattle show the U.S. coronavirus death toll could now hit 145,000 by August, NBC News reported Tuesday. If the prediction bears out, it would mean 30,000 more deaths would occur in the country in the next two months. As of Tuesday, nearly 111,000 COVID-19 deaths have been reported in this country. And in a confusing twist on the effort to understand how coronavirus spreads, a World Health Organization official said Monday that asymptomatic transmission of COVID-19 seems to be rare. Until now, experts believed that transmission by infected people who did not show any symptoms was a main driver of viral spread. “From the data we have, it still seems to be rare that an asymptomatic person actually transmits onward to a secondary individual,” Maria Van Kerkhove, the WHO’s technical lead for coronavirus response and head of…  read on >

The COVID-19 pandemic has had far-reaching effects, and a new study points to yet another: It may be keeping people from seeking emergency care for suicidal thoughts. The study, at one large Ohio health system, found that ER visits for suicidal ideation dropped by over 60% in the month after the state instituted its stay-at-home order. And that’s concerning, researchers said, because, if anything, this is a time when mental health needs are expected to be more acute than ever. “The question is: Where are these patients now?” said senior researcher Dr. Baruch Fertel of the Cleveland Clinic in Ohio. “Are they just brushing off their problems? Are they getting help through telemedicine instead?” Or, most worrisome, are some people going through with suicide instead of getting help? There is no way of knowing at this point, Fertel said, because figures are not available. “Unfortunately, we’ll only find out later, when we’re able to study suicide rates,” he said. The findings, published June 1 in the American Journal of Emergency Medicine, are the latest snapshot of how the COVID-19 pandemic has affected all aspects of medical care. U.S. studies have charted declines in everything from hospital admissions for heart attack, to organ transplants, to childhood vaccinations. In areas hard-hit by the disease, health systems were flooded, and non-urgent medical procedures put on hold. But even…  read on >

Back before coronavirus took over the headlines, every week seemed to bring another report about artificial intelligence besting human doctors at everything from diagnosing skin cancer to spotting pneumonia on chest X-rays. But these artificial intelligence (AI) tools — computer programs that get better at performing a task by being “trained” on the right kind of data — are years away from being used to help diagnose real-life patients, according to the doctors helping to develop and test them. “We still have a lot of unknowns in terms of generalizing and validation of these systems before we can start using them as standard of care,” said Dr. Matthew Hanna, a pathologist at Memorial Sloan Kettering Cancer Center in New York City. Generalizing means building an AI tool that can be used in multiple hospitals, and validation involves testing and adjusting an AI tool to ensure it’s accurate. “These are the types of studies we need to do to make sure these models are performing properly and not potentially harming patients,” Hanna explained. Meanwhile, humans are in no rush to swap their doctor for an AI diagnosis. In a 2019 New York University-Harvard study, business school students said they’d be OK with getting poorer quality health care as long as it was provided by a human instead of AI. People resisted AI, the study authors found,…  read on >

New York City finally reopened its economy on Monday after being the epicenter of the U.S. coronavirus pandemic for months, and a new study shows that stay-at-home orders may have been worth it, preventing nearly 60 million U.S. infections. The research, published in the Nature medical journal, examined how different social distancing policies and measures might have limited the spread of COVID-19, the Washington Post reported. A second study, from epidemiologists at Imperial College London and also published in Nature, found the shutdowns saved approximately 3.1 million lives in 11 European countries and dropped infection rates there by an average of 82 percent. In the first study, researchers at the University of California at Berkeley examined six countries — China, the United States, France, Italy, Iran and South Korea — and estimated how more than 1,700 different interventions, such as stay-at-home orders, business closings and travel bans, altered the spread of the virus. The report concluded that those six countries collectively managed to avert 62 million test-confirmed infections, which the researchers estimated would correspond to roughly 530 million total infections, the newspaper said. Surprisingly, school closures had no significant effect, although the authors said the issue requires further study, the Post reported. Meanwhile, New York City began to ease restrictions that had shut down schools, businesses and much of city life in March and April,…  read on >

When you’re searching for a misplaced item, it’s helpful to think about its color, size and shape. But Johns Hopkins researchers say traits you can’t see also come into play. The researchers said that volunteers found everyday items in clutter 20% quicker if they subconsciously factored in traits you can’t see, like hardness or softness. “Simply knowing the latent physical properties of objects is enough to help guide your attention to them,” said senior study author Jason Fischer, a cognitive neuroscientist in the department of psychological and brain sciences. “It’s surprising because nearly all prior research in this area has focused on a host of visual properties that can facilitate search, but we find that what you know about objects can be as important as what you actually see,” he said. For the study, Fischer’s team did experiments in which people tried to find everyday objects amid clutter. Some searches involved hardness of the missing object. Researchers found that people used the perception of hardness to find the object faster, but none of the participants was aware of doing so. “If you are searching for a sweater in a cluttered room, without any awareness of doing so you are able to avoid wasting time searching through the hard objects in the room and instead focus on the soft ones,” Fischer said. The greater the clutter,…  read on >

How you store your tomatoes doesn’t affect the flavor — what really matters is the type of tomato you choose, researchers say. A team from the University of Göttingen in Germany investigated the differences in flavor of ripe, picked tomatoes when stored in the refrigerator (44.6 degrees Fahrenheit) and at room temperature (68 degrees F). A panel of experienced taste-testers who judged the sweetness, acidity and juiciness of the tomatoes found no significant differences between those kept in the fridge and those stored at room temperature. The variety of tomato played a far bigger part in flavor than storage methods, according to the researchers. The study focused on two varieties of black cherry tomatoes. “It is the variety of tomato in particular that has an important influence on the flavor. Therefore, the development of new varieties with an appealing flavor can be a step towards improving the flavor quality of tomatoes,” lead author Larissa Kanski said in a university news release. She is a doctoral student in the Division of Quality Plant Products. Study co-author Elke Pawelzik said freshness is a key to flavor but short-term storage won’t hurt. “The shorter the storage period, the better it is for the flavor and related attributes,” said Pawelzik, head of the Division of Quality Plant Products. “However, we were able to show that, taking into account the…  read on >

An over-the-counter heartburn remedy is showing some potential as a symptom reliever for COVID-19, a small study finds. Famotidine, sold under the brand name Pepcid, appeared to improve symptoms in a group of 10 patients diagnosed with COVID-19, researchers reported online June 4 in the journal Gut. The patients’ self-reported symptoms began to feel better within a day or two of taking famotidine, the study authors said. “A clinical trial is now needed to formally test if famotidine works against COVID-19,” said lead researcher Dr. Tobias Janowitz, a medical oncologist and cancer researcher with Cold Spring Harbor Laboratory in New York. But don’t rush out to stock up on Pepcid just yet, warned Dr. Amesh Adalja, a senior scholar with the Johns Hopkins Center for Health Security in Baltimore. “This is a very small study that was observational in nature,” Adalja said. “It is very hard to draw any conclusions from it.” A clinical trial in which Pepcid’s effectiveness is compared against a placebo is essential to prove that the medication works, since it is being used in mild to moderate cases of COVID-19, Adalja said. “These are mild cases and mild cases do get better over time, so these cases have to be compared to placebo in order to see if this was actually just the natural course of infection or the famotidine,” Adalja…  read on >

Among patients in China with COVID-19, researchers found that those with high blood pressure had twice the risk of death from the coronavirus compared with patients who didn’t have high blood pressure. And patients with high blood pressure who were not taking drugs to control it were at even higher risk, the findings showed. However, the study only found an association and could not prove cause-and-effect. For the study, researchers in China and Ireland analyzed data on nearly 2,900 COVID-19 patients who entered one hospital in Wuhan, China, between Feb. 5 and March 15. Nearly 30% of these patients had a history of high blood pressure. The analysis revealed that 4% of patients with high blood pressure died versus 1% of other patients, according to the report published June 5 in the European Heart Journal. Among those not taking medication for their high blood pressure, 8% died. That compared with 3% of patients who were taking blood pressure medication. The researchers, led by Fei Li and Ling Tao from Xijing Hospital in Xi’an, then pooled that data with data from three other studies involving 2,300 high blood pressure patients. The investigators found that patients taking angiotensin-converting enzyme (ACE) inhibitors or angiotensin receptor blockers (ARBs) were less likely to die than patients on other blood pressure drugs. But the researchers stressed that due to the size…  read on >

COVID-19 is taking a heavy toll on Americans’ mental health, a new nationwide survey shows. Overall, psychological distress more than tripled between 2018 and this spring — from 4% of U.S. adults in 2018 to 14% in April. Beth McGinty, an associate professor at Johns Hopkins Bloomberg School of Public Health in Baltimore, said the findings, from a survey of 1,500 adults, suggest the need to prepare for a wave of mental illness once the pandemic passes. “It is especially important to identify mental illness treatment needs and connect people to services, with a focus on groups with high psychological distress including young adults, adults in low-income households, and Hispanics,” McGinty said in a university news release. The survey used a scale to gauge feelings of emotional suffering as well as symptoms of anxiety and depression. It found that distress was especially acute among younger adults. Among 18- to 29-year-olds, 24% reported feelings of distress this spring, compared to 4% in 2018, researchers found. Lower-income households also were keenly feeling the impact of the pandemic. Distress rose from less than 8% in 2018 to 19% in homes with a yearly income of less than $35,000, the survey found. And 18% of Hispanics reported psychological distress in 2020, up from 4% in 2018. Among Americans age 55 and older, psychological distress nearly doubled between 2018 and…  read on >

Federal data released Friday offered signs of hope on the economic front, as jobless numbers actually fell — from 14.7 percent in April to 13.3 percent in May. The economy, hit hard by stay-at-home orders and shuttered businesses tied to the coronavirus crisis, ended up adding 2.5 million job in May, as some Americans warily crept back to work, The New York Times reported. It was very welcome news: According to the Times the unemployment rate in April was the highest seen since the federal government began keeping record afters World War II. Many economists expect that unemployment numbers will slow further as states reopen and more employees return to work. However, none of the good economic news has curbed the onslaught of SARS-CoV-2, the virus behind COVID-19. By Friday, the U.S. coronavirus case count had topped 1.8 million and the death toll passed 108,000. And a new review shows that crowded protests against police brutality have occurred in every one of the 25 U.S. communities with the highest concentrations of new COVID-19 cases. The Associated Press analysis also found that some cities — Minneapolis, Chicago, Washington, D.C., and Los Angeles among them — have witnessed protests on multiple days. In some communities, such as Minneapolis where the protests started, the number of people hospitalized with COVID-19 has also been rising, the news agency added.…  read on >