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Obesity May Boost Effectiveness of a Lung Cancer Therapy

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Obesity is seldom a friend to health, but in one medical context it might give patients a slight advantage, new research suggests. Specifically, when Australian researchers looked at trials of atezolizumab, an immune system-based treatment for lung cancer, they found that the drug worked better in people who were overweight. The trial involved more than 2,100 people with the most common form of lung tumors, non-small cell lung cancer. About half of the participants were normal weight, about one-third were overweight and 7 percent were obese. About two-thirds of patients received the newer drug, atezolizumab, while the remaining third got an older drug, docetaxel. The researchers found that obesity — a body mass index (BMI) of 30 or above — “was associated with significantly improved overall survival in patients treated with atezolizumab, but not in those who received docetaxel.” What’s more, there seemed to be a “linear relationship.” As body weight rose in patients taking atezolizumab, so too did their odds for survival. The study was led by Dr. Ganessan Kichenadasse, a medical oncology researcher at the Flinders Centre for Innovation in Cancer. “This is an interesting outcome and it raises the potential to investigate further with other cancers and other anti-cancer drugs,” Kichenadasse said in a Flinders University news release. “While our study only looked at baseline and during treatment, we believe it warrants…  read on >

Festive Foods Can Leave Those on Restricted Diets Out in the Cold

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Elaborate feasts are a centerpiece of the holidays, but all that food can make people with restricted diets feel left out, a new study suggests. People whose allergies or health, religious or cultural norms keep them from sharing the meals with others can leave them lonely, researchers say. “Despite being physically present with others, having a food restriction leaves people feeling left out because they are not able to take part in bonding over the meal,” said researcher Kaitlin Woolley, an assistant professor of marketing at Cornell University. A review of seven previously published studies found that restricted diets predicted loneliness among both children and adults. In one experiment, for instance, when people without food restrictions were given restrictions, they felt lonely. This suggests that these feelings aren’t the result of other issues or just picky eating, Woolley said. More evidence came from people who attended a Passover Seder. When they were reminded that they couldn’t eat leavened foods, participants felt lonelier. But within their restricted group, they felt a stronger bond. In earlier research, Woolley found that strangers felt more connected and trusting when they shared the same food. Also, sharing food from the same plate increased cooperation between strangers. But restricted sharing makes people suffer “food worries,” she said. They’re concerned about what they can eat and if others will judge them for…  read on >

Recipes for Healthy Holiday Appetizers

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Finger foods are delicious, but they can pack on the calories even when you just nibble. Here are two appetizer makeovers with plenty of flavor and a lot less fat. Jalapeno poppers are a favorite thanks to their creamy filling and crunchy coating. By baking instead of deep frying them, you’ll cut back on hundreds of calories yet keep the crunch. Another crowd pleaser is taco dip. Ingredients with a lower fat content make all the difference in this recipe. Baked Jalapeno Poppers 12 fresh jalapeno peppers, halved lengthwise, stems, seeds and membranes removed 8 ounces reduced-fat cream cheese 1 cup grated part-skim mozzarella 1 teaspoon cumin or fennel seeds, slightly crushed 1 teaspoon mild ground chili powder 1/4 teaspoon freshly ground black pepper 1 egg 2 egg whites 1/2 cup whole wheat flour 1 cup seasoned breadcrumbs 1/2 teaspoon salt Note: Wear disposable gloves to prepare the jalapenos to minimize the capsaicin that gets on your fingers. Preheat oven to 350 degrees. Lightly coat a large baking sheet with nonstick spray and set aside. In a large bowl, mash together cream cheese, mozzarella, cumin or fennel seeds, chili powder and black pepper. In a shallow dish, whisk the egg and egg whites. Spread out the flour on a sheet of wax paper. Spread breadcrumbs on another sheet of wax paper. Fill each pepper half…  read on >

How You Can Be Overfat Without Being Overweight

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You know that you need to watch your weight to lower your risk for heart disease, but that is far from the whole story. It is possible to be overfat without being overweight, meaning that you’re storing fat within your body even though the scale says you’re at a normal weight. And that distinction is key when it comes to heart health. For decades, doctors have measured a patient’s body mass index, or BMI, as a way to determine the heart disease risk associated with obesity. (There are even online calculators that let you figure out your BMI on your own.) Basically, BMI determines the percentage of fat in your body related to your height and weight. But some evidence shows that the calculation may misclassify up to 50% of those at risk of heart disease from excess fat. That’s because fat is not all the same. Fat stored around the belly, called visceral fat, is associated with insulin resistance and other metabolic abnormalities. Evidence shows that someone with a large waistline — over 40 inches for men and 35 inches for women — is more at risk for heart disease than someone with a smaller waist, even if they have the same BMI. Who’s most at risk? There are genetic components that indicate that white men, black women and people from India and South…  read on >

Do Your Heart a Favor: Bike, Walk to Work

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Leave your car in the garage if you can: A new study suggests that walking or biking to work could cut your risk of a heart attack. The researchers analyzed 2011 data from 43 million working adults in England and found that 11.4% were active commuters, with 8.6% walking to work and 2.8% cycling to work. In areas where walking or cycling to work were more common in 2011, the incidence of heart attacks fell among men and women over the next two years. Major heart disease risk factors include inactivity, being overweight, smoking and diabetes, the study authors noted. After adjusting for those factors, the investigators found that women who walked to work in 2011 had a 1.7% lower risk of heart attack in the following year, and men who cycled to work had the same reduction in heart attack risk. The University of Leeds study was published online recently in the European Journal of Preventive Cardiology. The findings show “that exercise as a means of commuting to work is associated with lower levels of heart attack. The benefits of regular exercise are numerous and we support initiatives to help everyone become and stay active,” study co-author Alistair Brownlee said in a university news release. Lead author Chris Gale added, “Whilst we cannot conclusively say that active travel to work lowers the risk of…  read on >

Health Tip: Home Care for Stomach Cramps

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(HealthDay News) — Stomach cramps typically refer to abdominal pain or discomfort between your chest and groin. Causes range from constipation to food intolerance, says the Icahn School of Medicine at Mount Sinai. To help ease mild stomach cramps at home, Mount Sinai suggests: Sip water or other clear fluids. Only drink sports drinks in small amounts. Avoid solid food for the first few hours. If you’ve been vomiting, wait six hours and then eat small amounts of mild foods, such as crackers. Do not take any medicine without talking to your doctor. Call your doctor if stomach cramps are accompanied by other symptoms, such as persistent bloating, diarrhea, weight loss or fever.

The Financial Reward of Slimming Down

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If you’re overweight or obese, shedding pounds can help improve your health and your longevity. What’s more, doing so may also significantly boost your bank balance. Researchers at Johns Hopkins University in Baltimore wanted to know how a person’s expenses and income might change if their weight went from obese to overweight to normal at different ages. So they created a computer simulation that looked at a person’s health and weight over the years. They considered time lost from work, health complications related to being overweight — such as heart disease, high blood pressure and diabetes — and direct medical costs to insurers and health care facilities, among other things. How much could you save? If you’re 20, the research, which was published in the Journal of Obesity, found that slimming down from obese to overweight saves you more than $17,000 in direct medical costs and lost productivity over your lifetime. Reach a healthy weight and the savings exceed $28,000. If you’re in your 40s, going from obese to overweight saves you around $18,000. Drop to a healthy weight and you’ll net an average lifetime savings of about $31,000. Savings peak for those who slim down in the midlife years. A 50-year-old who goes from obese to overweight can see a lifetime savings of about $36,000. You’ll add even more cash to your wallet if…  read on >

To Avoid Falls, Check Your Balance

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Bad balance is a common cause of dangerous falls, especially among older adults. Falls send more than 2 million adults to the emergency room every year and often result in lengthy rehab stays. Preventing falls is a priority for staying healthy and preventing painful broken bones as you age. Easy strength and balance exercises that you can do anytime, anywhere, such as tai chi and yoga, can help you stay steady on your feet. But first it’s important to know how good (or lacking) your balance is. Grab a friend or loved one, a sturdy chair and a stopwatch to check your balance with a quick test called the single leg stance. It basically involves standing on one leg, and doctors use it to predict who might be at risk of falling. Stand barefoot in front of the chair but don’t touch it. Cross your arms. Lift one leg up off the floor and start the timer. As you feel yourself start to sway, immediately steady yourself with the chair and stop the timer. Here are the average times that indicate good balance when you stand on one leg based on age: Ages 18-39: 43 seconds for men and women Ages 40-49: 40 seconds for men and women Ages 50-59: 36 seconds for women, 38 for men Ages 60-69: 25 seconds for women, 28 for…  read on >

Fatty Diets Tied to Leading Cause of Vision Loss in Seniors

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Diets heavy in red meat and fatty foods could help spur a leading cause of vision loss in older Americans, new research suggests. The study found that people who ate more typical Western diets were three times more likely to develop an eye condition that robs you of your central vision — late-stage age-related macular degeneration. “What you eat seems to be important to your vision, and to whether or not you have vision loss later in life,” said study lead author Amy Millen. She’s an associate professor in the department of epidemiology and environmental health at the University at Buffalo’s School of Public Health and Health Professions, in Buffalo, N.Y. “People know that diet influences cardiovascular risk and the risk of obesity, but the public may not know that diet can affect vision loss,” Millen said. Age-related macular degeneration occurs when a part of the eye called the macula is damaged. Sometimes this happens when deposits called drusen grow on the macula. Or it can occur when new blood vessels keep forming and leak blood, scarring the macula, according to the American Academy of Ophthalmology. Genetics and smoking are known risk factors for age-related macular degeneration. The study included almost 1,300 people from a nationally representative sample. Most did not have macular degeneration. There were 117 who had early AMD, and 27 had late.…  read on >

Health Tip: Signs of a Herniated Disc

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(HealthDay News) — The bones that form your spine are cushioned by round discs. A herniated disc is a disc that has been pushed out of place, says the American Association of Neurological Surgeons. The group mentions warning signs of a herniated disc: Low backache. Numbness or weakness in parts of the body. A sharp, electric shock-like pain on one side of the body. Burning or tingling that radiates into the leg or shoulder. Sometimes, these symptoms can worsen with standing, walking or sitting.