Taking even high doses of supplementary vitamin D won’t lower an older person’s odds for type 2 diabetes, new research confirms. Vitamin D supplements may have other benefits, but in otherwise healthy folks with sufficient levels of the nutrient, “our findings do not suggest benefits of long-term moderate- or high-dose vitamin D3 supplementation” in warding off type 2 diabetes, the team of Finnish researchers concluded. They published their findings Dec. 2 in the journal Diabetologia. The new research followed on data from other studies that had suggested that people with especially low levels of vitamin D might face a higher risk for diabetes. That was true for people who were already prediabetic, especially. So could a relatively high dose of vitamin D supplements help lower type 2 diabetes rates among people without prediabetes — those at no special risk for the blood sugar disease? To find out, researchers led by Jirki Vyrtanen, from the University of Eastern Finland, randomly assigned nearly 2,300 people aged 60 or older to receive either placebo pills or 40 or 80 micrograms of vitamin D3 supplements per day, for five years. At the end of the five years, “105 participants developed type 2 diabetes: 38 in the placebo group, 31 in the group receiving 40 micrograms of vitamin D3 per day, and 36 in the group receiving 80 micrograms of vitamin… read on > read on >
All Eats:
Heart Trouble Harms Men’s Brains Far Sooner Than Women’s
Men with heart risk factors tend to lose their brain health more quickly than women with similar heart risks, a new study finds. These men face brain decline as early as their mid-50s, while women are most susceptible from their mid-60s onward, researchers report in the Journal of Neurology Neurosurgery and Psychiatry. “These results suggest that mitigating cardiovascular risk is an important therapeutic target in the prevention of Alzheimer’s disease, and indicate that this should be addressed aggressively a decade earlier in males than in females,” concluded the research team led by senior researcher Paul Edison, a professor of neuroscience with the Imperial College London. Heart disease risk factors like type 2 diabetes, obesity, high blood pressure and smoking have previously been associated with a higher risk of dementia, researchers said in background notes. However, it’s not been clear when these heart health factors begin to take their toll on brain health, and whether there’s any differences between men and women, researchers noted. For the study, researchers analyzed data on nearly 34,500 participants in the UK Biobank, an ongoing large-scale research project. Imaging scans helped track changes in the participants’ brains over time, and researchers calculated their heart disease risk using their recorded health data. Results showed that heart risk factors, obesity and high levels of belly fat caused a gradual loss of brain volume… read on > read on >
Skin Patch Could Monitor Your Blood Pressure
A wearable patch the size of a postage stamp that can monitor blood pressure continuously could soon help people manage their hypertension. Researchers at the University of California, San Diego, who developed the wearable ultrasound patch report Nov. 20 in the journal Nature Biomedical Engineering that it has worked well in tests with more than 100 patients. Maintaining a normal blood pressure — 120/80 — helps prevent many illnesses, from heart disease and stroke to kidney problems, dementia and vision loss, so many patients with high blood pressure use a cuff-and-meter device to track their levels. “Traditional blood pressure measurements with a cuff, which are limited to providing one-time blood pressure values, can miss critical patterns,” said study co-author Sai Zhou, who recently received his doctorate degree from the University of California, San Diego’s Jacobs School of Engineering. “Our wearable patch offers continuous stream of blood pressure waveform data, allowing it to reveal detailed trends in blood pressure fluctuations,” he added in a university news release. The soft, stretchy patch adheres to the skin and is worn on the forearm. An array of tiny transducers inside it send and receive ultrasound waves that track changes in the diameter of blood vessels. These changes are then converted into blood pressure values. Developers said the patch produces results comparable not only to those of a standard blood… read on > read on >
Trump Picks Vaccine Skeptic Robert F. Kennedy Jr. to Lead Health & Human Services
In a move guaranteed to alarm many, President-elect Donald Trump has chosen Robert F. Kennedy Jr., a vocal opponent of vaccines and other tenets of mainstream health care, to head the massive U.S. Department of Health and Human Services (HHS). The department encompasses numerous key agencies, including the U.S. Centers for Disease Control and Prevention, the U.S. Food and Drug Administration, the National Institutes of Health, Medicaid and Medicare. Trump’s nomination, which came Thursday, shifts the 70-year-old Kennedy from a fringe character railing against many long-accepted medical practices to one of the most powerful people in the federal government, charged with overseeing Americans’ health care and safety. In a statement, Trump, who has already said he’d let Kennedy “go wild on health,” reinforced his would-be appointee’s image as a maverick. “For too long, Americans have been crushed by the industrial food complex and drug companies who have engaged in deception, misinformation and disinformation when it comes to Public Health,” Trump said in a post on his Truth Social site announcing the nomination. Kennedy, he said, would “Make America Great and Healthy Again!” It’s been a dramatic arc for Kennedy, whose namesake father was assassinated in 1968 in the midst of a campaign to become the Democratic Presidential nominee that year. Kennedy Jr. was himself a Democrat until he campaigned in this year’s presidential campaign as… read on > read on >
Good Night’s Sleep Wards Off High Blood Pressure in Teens
High blood pressure is a rare health issue among teens, but U.S. case numbers are creeping upwards. Now, research published recently in the Journal of the American Heart Association, shows that healthy sleep can help keep hypertension at bay in the young. That’s probably because “disrupted sleep can lead to changes in the body’s stress response, including elevated levels of stress hormones like cortisol, which in turn can increase blood pressure,” explained study first author Augusto César Ferreira De Moraes. He’s an assistant professor of epidemiology at the University of Texas Health Science Center, in Houston. As the researchers noted, high blood pressure can affect a teenager: Data shows that about 1.7% of U.S. adolescents (averaging about 14 years of age) were diagnosed with hypertension in 2018-2020, and that number rose to 2.9% by 2020-2022. The new study looked at the same dataset, which included more than 3,300 kids who wore Fitbits that tracked their daytime activity and nighttime total sleep time, as well as their REM (deep) sleep. The study found that adolescents who got the age-recommended 9 to 11 hours of sleep nightly had a 37% lowered odds for high blood pressure “incidents,” compared to those who didn’t. Certain factors, such as the noise level of the neighborhood the teen lived in, didn’t impact the results, De Moraes and colleagues noted. There are… read on > read on >
Vitamin D Supplements Could Help Lower Blood Pressure in Obese People
Vitamin D supplements might lower blood pressure in seniors who are obese, reducing their heart health risk, a new study says. But taking more than the recommended daily dose will not provide additional health benefits, researchers report in the Journal of the Endocrine Society. “Our study found vitamin D supplementation may decrease blood pressure in specific subgroups such older people, people with obesity and possibly those with low vitamin D levels,” said researcher Dr. Ghada El-Hajj Fuleihan of the American University of Beirut Medical Center in Beirut, Lebanon. Studies have linked vitamin D deficiency to an increased risk of high blood pressure, researchers said in background notes. However, there’s not solid evidence whether taking vitamin D supplements can help lower blood pressure. The recommended daily dose of vitamin D is 600 IU, or about 15 micrograms, researchers said. For the study, researchers tracked the health of 221 seniors with obesity who took either 600 IU or 3,750 IU of daily vitamin D supplements for a year. The supplements did lower their blood pressure, results show, but higher doses did not provide additional benefits. “High vitamin D doses compared to the Institutes of Medicine’s recommended daily dose did not provide additional health benefits,” El-Hajj Fuleihan said in a news release. More information The Endocrine Society has more on vitamin D for preventing disease. SOURCE: The Endocrine… read on > read on >
Diabetes & Kidney Trouble Can Bring Heart Disease Decades Earlier
People with both type 2 diabetes and chronic kidney disease face a heart health double-whammy, a new study says. Men with both diabetes and kidney disease will develop heart health problems 28 years earlier than those without either condition, researchers reported today at an American Heart Association meeting in Chicago. Women with diabetes and kidney disease will develop heart problems 26 years earlier, results show. “Our findings help to interpret the combination of risk factors that will lead to a high predicted cardiovascular disease risk and at what age they have an impact on risk,” lead study author Vaishnavi Krishnan, a researcher at Northwestern University in Chicago and a medical student at Boston University School of Medicine, said in a news release. “For example, if someone has borderline-elevated levels of blood pressure, glucose and/or impaired kidney function, but they don’t yet have hypertension or diabetes or chronic kidney disease, their risk may not be recognized,” Krishan said. For the study, researchers used federal health survey data from 2011 to 2020 to create heart risk profiles for people who have type 2 diabetes, kidney disease, or both. Kidney disease and type 2 diabetes are two of the four components of cardiovascular-kidney-metabolic syndrome (CKM), which the heart association defines as the overall health risk that arises from the interplay of heart disease, kidney problems, diabetes and obesity.… read on > read on >
FDA Proposes Ban on a ‘Useless’ Decongestant, Phenylephrine
More than a year after its advisory panel unanimously declared the drug phenylephrine to be useless against nasal congestion, the U.S. Food and Drug Administration is proposing that it be removed from common over-the-counter decongestants. Products that include phenylephrine as an active ingredient include Sudafed PE, Vicks Sinex and Benadryl Allergy Plus Congestion. In fact, “it is important to note that some products only contain oral phenylephrine as a single, active ingredient,” the FDA said in a statement released Thursday. However, based on the available science, it’s time for consumers to stop throwing their money away on such products, the FDA said. “It is the FDA’s role to ensure that drugs are safe and effective,” Dr. Patrizia Cavazzoni, who directs the FDA’s Center for Drug Evaluation and Research (CDER), said in the statement. “Based on our review of available data, and consistent with the advice of the advisory committee, we are taking this next step in the process to propose removing oral phenylephrine because it is not effective as a nasal decongestant.” The agency said its experts poured over decades of data on whether or not phenylephrine could ease nasal congestion. They found no evidence to support the claim, nor any evidence to support the notion that phenylephrine might boost the effects of other medicines included in a decongestant, such as acetaminophen or dextromethorphan. At… read on > read on >
Novo Nordisk CEO Warns of Deaths Linked to Compounded Semaglutide
The head of the company that makes the diabetes and obesity drugs Ozempic and Wegovy has warned that compounded versions of the active ingredient in those medications have now been linked to at least 100 hospitalizations and 10 deaths. “Honestly, I’m quite alarmed by what we see in the U.S. now,” Novo Nordisk President and CEO Lars Fruergaard Jorgensen told CNN on Wednesday. “Patients who believe that they’re getting access to a safe product, and they believe they’re getting semaglutide … I know for a fact that they are not getting semaglutide, because there’s only one semaglutide, and that’s produced by Novo Nordisk, and we don’t sell that to others.” Compounded drugs are made by pharmacies or manufacturers other than the companies that make approved versions of those medicines, and they typically are allowed when there is a shortage of those drugs. Semaglutide, and other GLP-1 drugs like it, have experienced shortages in the past two years as millions of Americans have turned to the medications for help with significant weight loss. While semaglutide remains on the shortage list, Novo Nordisk noted last week that the last remaining dose in short supply — the lowest dose of Wegovy — is now listed as available, CNN reported. “We’re collaborating with the FDA, and I think they’re looking into what are some of the considerations they have… read on > read on >
Just 5 Extra Minutes of Exercise Per Day Could Lower Blood Pressure
It doesn’t take much: Adding just five minutes of exercise to your daily routine lowers your blood pressure and might cut your odds for heart disease, new research shows. “The good news is that whatever your physical ability, it doesn’t take long to have a positive effect on blood pressure,” said study lead author Jo Blodgett, from University College London (UCL). “What’s unique about our exercise variable is that it includes all exercise-like activities, from climbing the stairs to a short cycling errand, many of which can be integrated into daily routines.” Her team published its findings Nov. 6 in the journal Circulation. According to the researchers, high blood pressure affects almost 1.3 billion adults globally and is one of the biggest causes of premature death due to stroke and other causes. The new study focused on almost 15,000 adult volunteers who were given activity trackers to chart their daily involvement in six key activities: Sleep Sedentary behavior (such as sitting) Slow walking (less than 100 steps per minute) Fast walking (100 steps per minute or more) Standing More vigorous exercise (such as running, cycling or stair climbing) Each day, the average participant got seven hours of sleep, 10 hours of sedentary behavior such as sitting, three hours of standing, one hour of slow walking, one hour of fast walking and just 16 minutes of… read on > read on >