A top vaccine official at the U.S. Food and Drug Administration (FDA) is stepping down, warning that vaccine misinformation is coloring the country’s top health decisions. Dr. Peter Marks, director of the FDA’s Center for Biologics Evaluation and Research, said he will resign and retire by April 5. In a letter to the acting FDA commissioner obtained by The Associated Press, Marks said the new leadership under Health Secretary Robert F. Kennedy Jr. does not value science or transparency. “It has become clear that truth and transparency are not desired by the Secretary, but rather he wishes subservient confirmation of his misinformation and lies,” Marks wrote. Kennedy, who has a history of spreading vaccine misinformation, promised during his Senate confirmation that he would not change vaccine policies.  But since taking office, he has said he plans to closely review the safety of childhood vaccines — despite decades of research showing vaccines are safe and save lives. A former FDA official told reporters that Marks was told to either resign or be fired, The Associated Press reported. Marks played a major role in the country’s COVID response. He helped lead the fast-tracked development and approval of COVID vaccines and created the name and idea behind “Operation Warp Speed” — which helped get vaccines to people in record time. “RFK Jr.’s firing of Peter Marks because he…  read on >  read on >

Artificial intelligence (AI) can help improve how premature babies are fed, giving them a better chance at normal growth and development, a new study says. Currently, preemies in a neonatal intensive care unit are fed by IV, receiving a drip-drop handmade blend of nutrients that doctors call total parenteral nutrition, or TPN. This is the only way to feed newborns whose digestive systems haven’t matured enough to properly absorb nutrients, researchers said. “Right now, we come up with a TPN prescription for each baby, individually, every day,” senior researcher Nima Aghaeepour, an associate professor of pediatrics at Stanford University, said in a news release. “We make it from scratch and provide it to them.” Unfortunately, the process is error-prone, and it’s tough for docs to know if they’ve gotten the formula right, researchers said. There’s no blood test to measure whether a preemie has received enough daily calories, and preemies don’t necessarily cry when they’re hungry or become calm and content when they’re full. “Total parenteral nutrition is the single largest source of medical error in neonatal intensive care units, both in the United States and globally,” Aghaeepour said. To try to solve this problem, researchers trained an AI program on nearly 80,000 past prescriptions for preemie IV nutrition, linked to data on how the tiny patients fared. The AI uses information in a preemie’s…  read on >  read on >

Statins are very cheap and highly effective cholesterol-lowering drugs — but high-risk heart patients may have an even better option, a new evidence review says. Combining statins with another drug, ezetimibe, significantly reduces the risk of death in patients with clogged arteries, according to findings published March 23 in Mayo Clinic Proceedings. Using a high-dose statin with ezetimibe significantly reduces levels of “bad” LDL cholesterol, increasing a person’s chances of reaching healthy levels by 85%, researchers found. The combo also brought about a 19% reduction in risk of death from any cause; a 16% reduction in heart-related deaths; an 18% decrease in the risk of a major cardiovascular health problem; and a 17% decline in stroke risk. This combination therapy would prevent more than 330,000 deaths a year worldwide among patients who have already suffered a heart attack, including almost 50,000 deaths in the U.S. alone, researchers said. “This study confirms that combined cholesterol lowering therapy should be considered immediately and should be the gold standard for treatment of very high-risk patients after an acute cardiovascular event,” senior researcher Dr. Peter Toth, a professor of clinical family and community medicine at the University of Illinois, said in a news release. Up to now, studies have been inconsistent regarding whether to provide combo cholesterol-lowering therapy immediately for high-risk patients, even before they suffer a heart attack…  read on >  read on >

How should a person eat in middle age to protect their health as they grow older? One diet came out a clear winner in a 30-year study involving more than 105,000 men and women and eight diets, researchers reported in the journal Nature Medicine. People whose dietary pattern more closely stuck to the Alternative Healthy Eating Index (AHEI) in middle-age had the greatest likelihood of good health in their 70s, researchers say. Those with the highest AHEI score had 86% better odds of healthy aging at 70, and were 2.2 times more likely to be healthy at 75, results show. The AHEI centers on a diet rich in fruits, vegetables, whole grains, nuts, legumes and healthy fats, and low in red and processed meats, sugary drinks, sodium and refined grains, researchers said. “Our findings suggest that dietary patterns rich in plant-based foods, with moderate inclusion of healthy animal-based foods, may promote overall healthy aging and help shape future dietary guidelines,” co-senior researcher Marta Guasch-Ferré, an associate professor of public health at the University of Copenhagen and adjunct associate professor of nutrition at the Harvard T.H. Chan School of Public Health, said in a news release. Harvard researchers created the AHEI in 2002 as an alternative to the U.S. Department of Agriculture’s Healthy Eating Index, which measures how well people’s diets stick to the federal Dietary…  read on >  read on >

A rare red meat allergy, usually linked to a bite from the lone star tick, may also be caused by other tick species found in different parts of the U.S., a new report shows. “Alpha-gal syndrome is relatively rare, but those who have it can have a full-on anaphylactic shock,” Douglas Norris, a professor of molecular microbiology and immunology at the Johns Hopkins Bloomberg School of Public Health, said in a report from NBC News. The U.S. Centers for Disease Control and Prevention (CDC) estimates nearly 450,000 people in the U.S. have this condition. Most cases are linked to the lone star tick, which is common in the Southeast and lower Midwest.  But new case reports from Maine and Washington state found two women who developed alpha-gal syndrome after being bitten by ticks in places where lone star ticks aren’t common. This suggests that other types of ticks, like the black-legged tick (also called deer tick) that transmits the bacteria that causes Lyme disease, and the western black-legged tick, may also cause the condition. “We do believe the lone star tick is still responsible for most of the cases of alpha-gal syndrome in the U.S.,” Dr. Johanna Salzer, a veterinary medical officer and epidemiologist with the CDC’s Division of Vector-Borne Diseases, told NBC News. In the Washington case, a 61-year-old woman went into anaphylactic shock…  read on >  read on >

Tool is an online, searchable database that provides a consolidated list of contaminant levels  read on >