
Few heartbreaks are as devastating as when a beloved family dog falls ill with cancer. But a new research paper could spur development of more and better treatments for a canine companion who has a brain tumor — because it’s possible that those same therapies will help human kids, too. Dogs’ brain cancers are genetically akin to those found in children, a new study in the journal Cancer Cell reports. “These dog tumors were much more similar to the tumors we find in kids than the tumors we find in adults,” said senior researcher Roel Verhaak, associate director of computational biology at The Jackson Laboratory in Farmington, Conn. “This is important because it means whatever results we find in preclinical experimental therapy studies involving canines is going to be most applicable — and maybe even only applicable — to children’s brain tumors,” he added. Striving to cure pet dogs with brain tumors and learning which therapies work best — and why — could inform cancer treatments for children with these tumors, the researchers concluded. It’s been thought for some time that family dogs might be better for testing experimental cancer drugs than lab animals like mice or monkeys, said Dr. Len Lichtenfeld, deputy chief medical officer for the American Cancer Society. That’s because dogs live tightly alongside humans, sharing the same exposures from home and… read on >