Suffering from low back pain? Addressing your unhealthy lifestyle habits could help ease your pain better than traditional care, a new study says. Back pain sufferers who got lifestyle coaching functioned better and had improved quality of life compared to others who received standard care, researchers report in the study published Jan. 10 in the journal JAMA Network Open. “Resolving back pain needs to focus on more than the back,” senior investigator Chris Williams, a research fellow with the University of Sydney in Australia, said in a news release. “Our bodies are not like machines, we are more like ecosystems where lots of factors interact and determine how we work and feel,” Williams continued. “Back pain is no different.” For the study, nearly 350 people with low back pain were randomly assigned to receive either lifestyle coaching or standard care conducted under existing guidelines. Physical therapists, dietitians and telephone health coaches helped people assigned to the coaching group figure out which of their lifestyle habits might be making their back pain worse. These risk factors could include excess weight, lack of physical activity, bad diet, poor sleep, smoking or excessive alcohol use, researchers explained. For six months, the coaching group was provided support to help them address the factors potentially linked to their back pain. By the end of the study, people in the lifestyle…  read on >  read on >

Women past menopause can protect themselves from future fractures through infrequent, cheap IV infusions of a bone-strengthening drug. Women 50 to 60 who got two IV infusions of zoledronate (Reclast) within five years had a 44% lower risk of spinal fractures, compared to women who received a placebo, according to results published Jan. 15 in the New England Journal of Medicine. They also had a lower risk of major fractures related to osteoporosis and fragility fractures caused by little to no trauma, results show. “The results show that prevention of vertebral fractures in early postmenopausal women is possible with very infrequent infusions of zoledronate,” concluded the research team led by Dr. Mark Bolland, an associate professor of medicine with the University of Auckland in New Zealand. “The cost of the treatment, either to individual patients or to health systems, is likely to be low because the drug is generic and the frequency of administration low,” the team added. At menopause, women have a 50% lifetime risk of suffering from a fracture, particularly as their bones grow thin and frail through the aging process, researchers said in background notes. Zoledronate is used to treat or prevent osteoporosis caused by menopause, but it hadn’t been tested to see if early treatment could prevent bone loss in early postmenstrual women, even those with good bone density at the…  read on >  read on >

FRIDAY, Jan. 17, 2025 (HealthDay News) — Brain tissue samples are essential for scientific research, especially when it comes to brain disorders such as autism spectrum disorder. Not surprisingly, samples are hard to get. Despite the great need for brain tissue, donations remain rare and aren’t easily collected.  In an article published in Dec. 2024 in the journal Frontiers in Neurology, researchers describe the critical role that brain tissue plays in autism scientific research. The authors’ explain what many families of people with autism know. “The basis for an individual’s autism is not determined, the underlying biological mechanisms are poorly understood, and clinical care is often suboptimal,” they write. Experts rarely understand the exact factors that contribute to autism, and there is much to learn about causes, diagnosis and treatment. What’s more, autism symptoms vary greatly. Anxiety, sleep problems, epilepsy and gastrointestinal problems are some common co-occurring conditions. Noted in the study is Autism BrainNet, a program set up to educate autistic people and their families about the opportunity to donate brain tissue, the process, and the legacy for research created by individual donors.  Surprising facts about brain donation It’s a comforting process during a painful time for these families, according to David G. Amaral, Scientific Director of Autism BrainNet and Distinguished Professor at the UC Davis MIND Institute and Department of Psychiatry and Behavioral Sciences.…  read on >  read on >

Smokers are better able to quit if they’re offered financial incentives for their efforts. Overall, smokers had up to a 54% better chance at kicking the habit if their quit program offered them cash or vouchers as a reward, researchers found in a new evidence review published Jan. 13 in the Cochrane Database of Systematic Reviews. These incentives made even more of an impression on pregnant smokers, who were more than twice as likely to quit long-term if provided rewards, the review says. “Smoking is the leading preventable cause of ill health and early death worldwide, and quitting smoking is vitally important to help people live in good health for longer,” lead researcher Caitlin Notley, professor of addiction sciences at University of East Anglia’s Norwich Medical School, said in a news release. “We are now very confident that incentives help people, and pregnant people too, to quit smoking better than not offering incentives,” Notley added. Up to now, the evidence regarding financial incentives for quitting smoking hasn’t been solid, researchers noted. But an evaluation of 47 previous studies, including 14 newer papers, “found high-certainty evidence this time that indeed they help people who are pregnant quit smoking and stay quit,” senior researcher Jamie Hartmann-Boyce, assistant professor of health policy and promotion with the University of Massachusetts Amherst School of Public Health and Health Sciences, said…  read on >  read on >

The way obesity is diagnosed needs to become more sophisticated, an international commission has concluded. Using body-mass index (BMI) to tell who is overweight or obese is not reliable, and can result in misdiagnosis, the Commission on Clinical Obesity says in a new paper published today in The Lancet Diabetes & Endocrinology. “People with excess body fat do not always have a BMI that indicates they are living with obesity, meaning their health problems can go unnoticed,” commission member Dr. Robert Eckel, chair of atherosclerosis with the University of Colorado Anschutz Medical Campus said in a news release. “Additionally, some people have a high BMI and high body fat but maintain normal organ and body functions, with no signs or symptoms of ongoing illness,” Eckel added. Instead of BMI, the commission recommends that obesity be diagnosed through one of these methods: Using another measurement of body size (waist circumference, waist-to-hip ratio or waist-to-height ratio) along with BMI. Using two of those body size measurements without BMI. Making direct measurements of body fat using sophisticated scans. Assuming that people with very high BMI above 40 are clinically obese. “Relying on BMI alone to diagnose obesity is problematic as some people tend to store excess fat at the waist or in and around their organs, such as the liver, the heart or the muscles, and this is…  read on >  read on >

All women 65 and older should continue to be screened for osteoporosis, the nation’s leading preventive health panel says in an updated recommendation. The U.S. Preventive Services Task Force also recommends screening women younger than 65 who’ve gone through menopause and are at increased risk of a fracture from bone loss, according to the updated guidelines published in the Journal of the American Medical Association. “Too often, the first sign of osteoporosis is a broken bone, which can lead to serious health issues,” USPSTF member Dr. Esa Davis said in a statement from the group. “The good news is that for women 65 years or older, as well as younger women at increased risk, screening can detect osteoporosis early—before fractures happen—helping women maintain their health, independence, and quality of life,” added Davis, senior associate dean of population and community medicine at the University of Maryland School of Medicine. Osteoporosis happens as people grow older and their bones lose the ability to regrow and replenish themselves. As bones become thinner and less dense, the risk of a bone fracture grows worse. Bones most commonly broken due to osteoporosis include the hips, wrists and spine, according to the Cleveland Clinic. The updated guideline for women is consistent with earlier versions issued in 2018 and 2011. The USPSTF regularly reviews each of its screening guidelines, to make sure…  read on >  read on >

It takes a village to help a smoker quit. And a new study published recently in JAMA Internal Medicine shows that smokers had a nearly doubled success rate quitting when supported by an integrated approach that included medication and personal counseling. “Our study demonstrates that providing access to effective medications and trained tobacco cessation specialists offers the greatest chance at successfully quitting and, hopefully, avoiding the potential of lung cancer,” principal investigator Paul Cinciripini, executive director of the University of Texas MD Anderson Cancer Center’s Tobacco Research and Treatment Program, said in a news release from the college. Lung cancer is the top cancer killer in the U.S., accounting for one in five cancer-related deaths, researchers said in background notes. Tobacco use is responsible for 85% of lung cancer cases and contributes to nearly 30% of all cancer-related deaths, researchers added. The average smoker requires several attempts before they’re able to break their nicotine addiction and quit, researchers said. For this study, researchers recruited a group of 630 smokers between 2017 and 2021. The smokers were at least 50, and smoked an average 20 cigarettes a day. The smokers were randomly assigned to one of three groups, each containing 210 people. One group was provided nicotine replacement therapy or medication and access to phone-based support. The second received the same, only prescribed by a lung…  read on >  read on >

Eating disorders appear to be linked to differences in brain structure among teenagers. Young adults who develop eating disorders appear to have delayed brain maturation as teenagers, MRI scans show in a new study published Jan. 10 in the journal Nature Mental Health. In particular, reduced maturation of the cerebellum — a brain region that controls appetite — helped explain an increased risk of unhealthy dieting or purging by age 23, researchers said. “Our findings reveal how delayed brain maturation during adolescence links genetics, mental health challenges and disordered eating behaviors in young adulthood, emphasizing the critical role of brain development in shaping eating habits,” lead researcher Xinyang Yu, a doctoral student at the King’s College London Institute of Psychiatry, Psychology & Neuroscience, said in a news release from the university. For the study, researchers analyzed data from nearly 1,000 people in England, Ireland, France and Germany. The participants all underwent MRI scans at ages 14 and 23, provided samples for genetic analysis, and completed questionnaires related to their eating habits. By 23, about 42% of the participants had healthy eating behaviors, 33% tended to diet and purge, and 25% were binge eaters, researchers noted. Eating disorders were linked to emotional problems in their teenage years like anxiety and depression, researchers found, as well as behavioral problems like hyperactivity. Anxiety and depression also significantly increased…  read on >  read on >

MONDAY, Jan. 13, 2025 (HealthDay news) — The sleep aid Ambien could be allowing toxic proteins to pollute the brain, potentially increasing a person’s risk of disorders like Alzheimer’s disease. Drugs like the main ingredient in Ambien, zolpidem, suppresses a system designed to clear protein waste from the brain during dreamless sleep, a mouse study published Jan. 8 in the journal Cell shows. The study “calls attention to the potentially detrimental effects of certain pharmacological sleep aids on brain health, highlighting the necessity of preserving natural sleep architecture for optimal brain function,” senior researcher Dr. Maiken Nedergaard, co-director of the University of Rochester Center for Translational Neuromedicine, said in a news release. For the study, researchers used brain imaging along with electrical brain readings to track the activity in lab mice of the glymphatic system, a brain-wide network responsible for clearing away waste proteins. They found that tightly synchronized oscillations occur in the brain during deep sleep, involving cerebral blood, spinal fluid and the biochemical norepinephrine. Norepinephrine is a brain chemical involved in the “fight or flight” response, and is associated with arousal, attention and stress. During sleep, norepinephrine triggers rhythmic constriction of blood vessels independent of a person’s heartbeat, researchers found. This oscillation generates the pumping action that powers the glymphatic system, which removes toxic proteins like tau and amyloid — proteins known to…  read on >  read on >

A fecal transplant could help people whose type 1 diabetes has fouled up their digestive system. Swallowing a handful of capsules filled with donor feces helped ease gut pain, nausea, bloating and diarrhea stemming from diabetes, researchers reported in a study published recently in the journal EClinicalMedicine. “The patients experienced a significant improvement in their quality of life and symptoms, far beyond what we observed with placebo,” lead researcher Dr. Katrine Lundby Høyer, a gastroenterologist with Aarhus University Hospital in Denmark, said in a news release from the college. This is the first time fecal transplant has been tested in type 1 diabetics against a placebo, and “the results are very promising,” Høyer added. As many as a quarter of type 1 diabetics suffer from diabetic gastroenteropathy, a condition in which the nerves that regulate the GI tract become damaged. Few treatment options are available, so researchers decided to see if a fecal transplant might be able to restore gut health in these patients, Høyer said. In fecal transplant, bacteria from a healthy person’s gut is transferred into a person with GI problems. The procedure is frequently used to treat C. difficile, a harmful bacteria that can cause severe diarrhea if it colonizes a person’s gut. For this study, researchers recruited 20 type 1 diabetes patients and randomly assigned them to receive either a fecal…  read on >  read on >