
Carefully targeted deep brain stimulation might one day enhance long-term memory, a small study suggests. The experiment involved just 14 epilepsy patients, all of whom had undergone an invasive procedure to insert electrodes deep within their brains as a means of identifying the source of future seizures. Taking advantage of the opportunity, the researchers asked the patients to participate in an additional memory study that involved presenting them with a series of 200 computerized images. Some of the images were viewed without any additional intervention. But some were viewed in tandem with exposure to highly controlled electrical impulses directed towards a specific part of the brain called the amygdala. The amygdala is known to be a key center for the regulation and processing of both emotions and memory. The result? “We found that delivering small-amplitude brief electrical pulses at a particular frequency just after a patient viewed an image on a computer screen would significantly enhance their ability to recognize that same image the next day,” said study co-author Dr. Jon Willie. How? Willie said deep brain stimulation appeared to spark immediate changes in brain activity. And that led his team to conclude that “this type of amygdala-mediated memory enhancement works by telling the brain to prioritize certain experiences to remember later.” Willie is an assistant professor of neurosurgery at Emory University’s departments of neurosurgery… read on >