A study based on online Google searches suggests surging U.S. interest in microdosing psychedelics, such as psilocybin, as rules around the use of such drugs begin to relax. But the safety of these drugs isn’t entirely clear, said study lead author Dr. Kevin Yang. “As public interest in using psychedelics and cannabis for health grows, it’s crucial that the medical community conducts studies to establish a strong evidence base for their safety and efficacy,” said Yang, a psychiatry resident physician at the University of California, San Diego (UCSD) School of Medicine. ‘Magic mushrooms’ have long been used recreationally to get high, but in recent years numerous studies have suggested that the fungus’ active ingredient, the hallucinogen psilocybin, might have some therapeutic effects if used in smaller doses (“microdosing”) under controlled conditions. According to a UCSD news release, people who microdose take “‘sub-perceptual’ doses of psychedelics, often over prolonged periods, with users claiming it improves cognition, mood and overall health without causing the intense hallucinogenic effects of higher doses.” Already, eight U.S. states have had cities or counties decriminalize this type of psychedelic use, and two states, Colorado and Oregon, have legalized psychedelic-assisted therapy and decriminalized psychedelics statewide. Those moves come at the same time that another recreational drug, cannabis, has gained mainstream acceptance and has been legalized in 24 states. So what is the current…  read on >  read on >

People largely date and marry people in their own “league,” as far as beauty is concerned, a new review finds. Men and women are fairly accurate at rating their own physical attractiveness, and they tend to choose mates who have similar views of their own beauty, researchers report. For example, fellows who rated themselves as attractive tended to date ladies with similar self-ratings, researchers reported recently in the journal Personality and Individual Differences. These results come from more than two dozen studies involving nearly 1,300 opposite-sex couples dating as far back as 1972. In the studies, members of couples were asked to rate their own physical attractiveness. Their pictures were then shown to strangers, who provided an outside rating on their beauty. People’s own assessment of their attractiveness largely tended to align with the rating provided by a stranger, results show. “The fundamentals of what humans consider to be attractive across cultures and across time are pretty consistent,” said lead researcher Gregory Webster, a professor of psychology at the University of Florida. The review also allowed researchers to track how these self-ratings change at different points in long relationships. Some studies focused on young dating couples, while others involved long-married spouses. Among people who had been together longer, men were more accurate at judging their own attractiveness, researchers found. That might be due to the…  read on >  read on >

Exposure to air pollution as a child increases an adult’s risk of bronchitis, a new study warns. Young adults with bronchitis symptoms tended to have been exposed during childhood to two types of air pollutants, researchers found: Particle pollution from dust, pollen, wildfire ash, industrial emissions and vehicle exhaust. Nitrogen dioxide from gasoline engines. Bronchitis occurs when the large airways of the lungs become inflamed, causing severe coughing spells that bring up mucus or phlegm. Wheezing, chest pain and shortness of breath are other symptoms. “Our results suggest that childhood air pollution exposure has more subtle effects on our respiratory system that still impact us in adulthood,” said researcher Dr. Erika Garcia, an assistant professor of population and public health sciences at the University of Southern California Keck School of Medicine. “Reducing air pollution would have benefits not only for current asthma in children but also for their respiratory health as they grow into adulthood,” Garcia added in a university news release. Air pollution has been consistently associated with lung ailments among children, and childhood lung problems are consistently associated with lung issues as adults, researchers said in background notes. However, few studies have explored the effect of childhood air pollution exposure on adult lung health, whether or not kids suffered lung problems, researchers said. Children are particularly vulnerable to the effects of air pollution, researchers…  read on >  read on >

It’s a nasty cycle: Chronic migraine sufferers who use too much pain medication sometimes get smacked with rebound headaches. But new research suggests that a medication commonly used to prevent migraines may also help fend off rebound headaches.  The study of 755 people with chronic migraine — meaning 15 or more headache days a month with migraines on eight or more — found that those who overused pain meds had fewer headache days when taking the migraine prevention drug atogepant (Quilipta). “There is a high prevalence of pain medication overuse among people with migraine as they try to manage what are often debilitating symptoms,” explained study author Dr. Peter Goadsby, from King’s College London. “However, medication overuse can lead to more headaches called rebound headaches, so more preventive treatments treatments are needed.” Two-thirds of the participants, who reported their headache and medication history, met the criteria for medication overuse. That means they took pain relievers such as aspirin, acetaminophen or non-steroidal anti-inflammatory drugs (NSAIDs) on 15 or more days a month; migraine drugs called triptans or ergots for 10 days or more; or any combination for 10 days or more. On average, participants reported 18 to 19 migraine days a month and using pain meds on 15 to 16 days. For 12 weeks, they were given 30 milligrams (mg) of atogepant twice daily; 60 mg…  read on >  read on >

Acupuncture can help breast cancer patients deal with the hot flashes that often accompany hormone therapy, a new clinical trial says. Nearly 2 in 3 women who got acupuncture during hormone therapy reported fewer and less intense hot flashes, results show. Hormone therapy blocks the effect of estrogen and other hormones that powers some breast cancers. Unfortunately, 4 in 5 patients (80%) experience hot flashes and other side effects associated with hormone deficiencies, researchers said. This causes some patients to drop hormone therapy, increasing their risk of cancer progression and death. “By managing side effects, our approach makes it easier for patients to continue their prescribed medication, which has the potential to reduce the risk of cancer recurrence and improve long-term outcomes for breast cancer survivors,” researcher Weidong Lu, lead oncology acupuncturist at the Dana-Farber Cancer Institute in Boston, said in a news release. For the study, researchers recruited 158 women with early to advanced breast cancers who were receiving hormone therapy. Half were randomly assigned to receive acupuncture twice a week for 10 weeks. About 64% of women who got acupuncture reported improvement in the number and severity of their hot flashes, compared to 18% of women not receiving acupuncture, results show. They also reported greater improvements in quality of life. After 10 weeks, the women not initially chosen also were given acupuncture, and…  read on >  read on >

Many sexually transmitted diseases are on the rise in the United States, and a nationwide poll indicates that ignorance about how they’re transmitted could be fueling their spread. About a third of Americans (34%) falsely believe sexually transmitted infections (STIs) can only be transmitted through sexual intercourse, poll results show. In fact, they can also be transmitted by kissing, sharing needles and during childbirth. It also found that 1 in 5 Americans (20%) think they only need to be tested for STIs if they are experiencing symptoms. “We’re likely still experiencing some of the effects of the COVID-19 pandemic when STI prevention services were completely shut down,” researcher Dr. Jose Bazan, a professor of clinical internal medicine with Ohio State University’s Division of Infectious Diseases, said in a news release. Syphilis cases have jumped 80% over a five-year period, researchers said in background notes. Worse, cases of congenital syphilis – in which women pass the bacteria to their babies during pregnancy – increased 180% between 2018 and 2022, according to the U.S. Centers for Disease Control and Prevention (CDC). During the pandemic, “a lot of STIs were undiagnosed and under-reported then, allowing these infections to spread within the population,” Bazan said. “It’s important that pregnant individuals get screened for syphilis as this is a very preventable infection that can easily be treated with antibiotics. Unfortunately,…  read on >  read on >

A full third of American adults take multivitamins, despite prior studies suggesting they do little to boost health. Now, a study involving almost 400,000 people finds zero benefit from multivitamin use in helping folks live longer. Among people “without a history of major chronic diseases, we did not find evidence to support improved longevity among healthy adults who regularly take multivitamins,” concluded a team led by Erikka Loftfield. She’s with the Division of Cancer Epidemiology and Genetics at the U.S. National Cancer Institute (NCI). Her team published its findings June 26 in the journal JAMA Network Open. In the study, Loftfield’s group analyzed data from three prospective studies (meaning people were followed over time) with an average 27 years of follow-up. Over 390,000 healthy adults were enrolled in the studies, and they averaged about 61 years of age upon study entry. Researchers gathered data on the participants’ multivitamin use. Over the nearly three decades of follow-up, almost 165,000 of the participants died. About 50,000 deaths were attributed to cancer, about 35,000 deaths were caused by heart disease and 9,275 deaths were linked to strokes. However, Loftfield’s group detected no association between multivitamin use and a person’s odds of dying within the study period. In fact, “we found that daily multivitamin use vs nonuse was associated with 4% higher mortality [death] risk,” the researchers noted. People’s…  read on >  read on >

Gun violence in the United States has become a national public health crisis, the U.S. Surgeon General declared Tuesday. “Today, for the first time in the history of our office, I am issuing a Surgeon General’s Advisory on firearm violence. It outlines the urgent threat firearm violence poses to the health and well-being of our country,” Dr. Vivek Murthy said in a news release announcing the new health advisory. “As a doctor, I’ve seen the consequences of firearm violence up close,” he added. “These are moms and dads, sons and daughters, all of whom were robbed of their physical and mental health by senseless acts of violence.” “Unfortunately, the problem has continued to grow. Fifty-four percent of adults in America report that they or family member have experienced a firearm-related incident, whether they’ve been personally threatened with or injured by a firearm, lost a family member, witnessed a shooting or shot a firearm in self-defense.” Some Americans are harmed more than others, Murthy noted. “Black individuals endure the highest rates of firearm homicides, while suicide rates are highest among veterans, older white individuals and younger American Indian or Alaska Native people,” he said. “What is especially devastating is how this has affected our children. Firearm violence has become the number one cause of death among children and adolescents, more than car accidents or drug overdoses.”…  read on >  read on >

Weight-loss drugs like Wegovy can improve symptoms in heart failure patients, a new clinical trial shows. Both men and women showed improved heart function after a year on semaglutide, the active ingredient in Ozempic and Wegovy, researchers report. Women tended to lose more weight than men, on average about 9.6% of their body weight compared with 7.2% in men. However, both genders experienced similar improvements regarding their heart health, researchers found. This could mean the drug might have heart benefits above and beyond helping people lose weight. The results shed light on “the consistent benefits of semaglutide for women and men,” said senior researcher Dr. Mikhail Kosiborod, a cardiologist at Saint Luke’s Mid-America Heart Institute in Kansas City, Mo. For the clinical trial, researchers randomly assigned 1,145 people with heart failure to take either semaglutide or a placebo for a year. Heart failure occurs when the heart starts to pump less efficiently, slowing the delivery of oxygen-rich blood throughout the body. This results in fatigue and shortness of breath, making everyday activities like walking or carrying groceries very difficult for some, according to the American Heart Association. But people on semaglutide experienced improvement in both their heart failure symptoms and the physical limitations the condition placed upon them, trial results show. They also had lower blood pressure and a smaller waist circumference after a year…  read on >  read on >

Losing weight can protect you against cancers related to obesity, a new study finds. Obesity has been linked to higher risk of at least 13 types of cancer, researchers said. This is largely due to excess levels of hormones like estrogen and insulin. But study results show that dropping pounds can improve a person’s odds against developing these cancers, including breast, kidney, ovary, liver and pancreatic cancers. “This study reinforces how crucial it is to treat obesity as a chronic disease,” said researcher Dr. Kenda Alkwatli, a clinical fellow at Cleveland Clinic. “We are hopeful that these results can help us better understand how we can use weight loss to address co-morbidities, including cancer in patients with obesity.” For the study, researchers evaluated the electronic health records of more than 100,000 obese patients at the Cleveland Clinic, of whom more than 5,300 developed cancer. Researchers tracked changes in BMI at three-, five- and 10-year intervals prior to a person’s cancer diagnosis and compared them against controls. They found that losing weight could reduce a person’s risk of developing most obesity-related cancers within a five-year span. For example, the risk of kidney cancer dropped within three years and endometrial cancer at three and five years. Multiple myeloma risk fell within 10 years. What’s more, losing weight also appeared to protect people against a range of 16…  read on >  read on >