Ozempic, a type 2 diabetes drug that has increasingly been used to help with weight loss, will now be labeled as having the potential to block intestines. The U.S. Food and Drug Administration recently made the label update for the drug made by Novo Nordisk, without directly citing Ozempic as the cause for this condition. “Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure,” the label reads. The side effect, known by the medical term “ileus,” is also listed on labels for the weight-loss drug Wegovy, also made by Novo Nordisk, and in the diabetes medication Mounjaro, made by Eli Lilly, CBS News reported. Both Ozempic and Wegovy are known generically as semaglutide. Among more than 8,500 reports of gastrointestinal disorders after using semaglutide medications through June 30, ileus is mentioned in 33 cases, including two deaths, CBS News reported. The two pharmaceutical companies that make these medications are both being sued for claims that the drugs can cause a similar health issue known as gastroparesis, or stomach paralysis, CBS News reported. More information The U.S. National Library of Medicine has more on ileus. SOURCE: CBS News read on >
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PTSD Can Harm a Woman’s Sex Life
Suffering from PTSD may take a toll on your sex life if you’re a woman, new research reveals. About 10% of women have PTSD symptoms because of combat exposure, childhood abuse and sexual violence. Little research has been done looking at how these symptoms might affect sexual functioning among midlife women. “As women age, there are many reasons why sexual functioning may become an issue for them,” said Dr. Stephanie Faubion, medical director for the North American Menopause Society. “This study highlights the need for health care professionals to ask about any history of trauma and open up the dialogue with their patients on this sensitive issue,” she said in a society news release. Researchers studied this in more than 100 postmenopausal women ages 45 to 66. The authors accounted for factors such as age, race/ethnicity, education, vaginal estrogen use, alcohol use and depressive symptoms. Study participants needed to have met certain criteria — they had to have experienced PTSD symptoms and had sexual activity within the month prior to evaluation. On average, women who reported moderate and severe PTSD symptoms also reported lower sexual functioning. The authors then considered specific aspects of PTSD symptoms. They found that greater avoidance/numbing symptoms were related to poorer sexual functioning. The results will be presented Wednesday during the Menopause Society’s annual meeting, in Philadelphia. Findings presented at medical… read on > read on >
Strike a Pose: Yoga Helps Heart Failure Patients
Heart failure can make everyday activities and exercise tough to carry out, but yoga might be a beneficial add-on to standard care. A new study from India finds this ancient practice improves quality of life and cardio functioning. “Our patients observed improvement in systolic blood pressure and heart rate compared to patients who were on medication without yoga,” said lead study author Ajit Singh, a research scientist at Manipal Academy of Higher Education. (Systolic blood pressure is the first number in a blood pressure reading.) In heart failure, the heart muscle is either too weak or too stiff to pump properly. This can lead to fluid buildup, shortness of breath and other complications. How might yoga help? “Yoga is a combination of mind-body techniques, which is a set of physical exercises [asana] with breathing techniques [pranayama], relaxation and meditation that can be effectively used to stimulate physical and mental well-being,” Singh explained in an American College of Cardiology news release. For the study, the researchers enrolled 75 heart failure patients between the ages of 30 and 70 at a care center in South India. They had received recommended therapy for the previous six months to one year. Each had what’s called left ventricular ejection fraction (LVEF) of less than 45%, a sign of mild to moderate dysfunction, according to the U.S. National Institutes of Health.… read on > read on >
Water Beads Can Expand Inside Body, Causing Kids Serious Harm. Should They Be Banned?
Ashley Haugen’s 13-month-old daughter, Kipley, woke up projectile vomiting in their Texas home one morning in July 2017. The Haugens took her to the doctor after it became apparent she wasn’t keeping anything down. After not responding to medication, Kipley was whisked to a nearby children’s hospital for emergency surgery. “I remember [the surgeon] showing us the picture of the material that he pulled out of Kipley’s small intestine,” Haugen recalls. “He was like, ‘I found this inside her small intestine, do you know what this is?’ And we recognized it immediately as the birthday gift that we had gotten for Abigail,” their 6-year-old daughter. The obstruction was a water bead — a tiny, super-absorbent pellet of gel that expands into a soft, slippery, squishy ball when soaked in water. Water beads are sold as toys and “sensory aids” for children, but regulators and consumer advocates are putting out an alert that the beads pose a health hazard to children. Kids can easily ingest the beads, which can cause choking or intestinal blockage as they absorb water from the body. Some kids have inserted the beads into their noses or ears, suffering damage as the gel expands, experts said. In some cases, beads have even wound up in children’s lungs. Some of the colorful beads start as tiny as a candy sprinkle and then grow… read on > read on >
Ginger May Ease Inflammation of Autoimmune Diseases
Ginger supplements may help those with certain autoimmune diseases, such as lupus and rheumatoid arthritis, control inflammation. New research has added evidence to support the impact of ginger on white blood cell function, particularly a type of cell called a neutrophil. The researchers were particularly interested in neutrophil extracellular trap (NET) formation, also called NETosis, and its role in controlling inflammation. When healthy people take ginger, the study found, their neutrophils are more resistant to NETosis. NETs are microscopic spider web-like structures. They propel inflammation and clotting, which contribute to many autoimmune diseases, including lupus and rheumatoid arthritis. “There are a lot of diseases where neutrophils are abnormally overactive,” senior co-author Dr. Kristen Demoruelle, associate professor of medicine at the University of Colorado School of Medicine, said in a university news release. “We found that ginger can help to restrain NETosis, and this is important because it is a natural supplement that may be helpful to treat inflammation and symptoms for people with several different autoimmune diseases.” A clinical trial with healthy volunteers showed that a week of daily intake of 20 mg of gingerols boosted a chemical inside the neutrophil called cAMP. These high levels of cAMP then inhibited NETosis’ response to the disease. “Our research, for the first time, provides evidence for the biological mechanism that underlies ginger’s apparent anti-inflammatory properties in people,”… read on > read on >
How to Care for a New Body Piercing
Piercings can be a fun way to express yourself, but they can also cause complications — particularly in areas that aren’t the earlobes — and need proper care. “The first step to caring for your piercing is choosing a qualified piercer,” said Dr. Steven Daveluy, an associate professor and program director at Wayne State Dermatology in Michigan. “Select an experienced piercer in a licensed studio. Then, properly care for your new piercing afterward to prevent problems, such as an infection or your piercing closing.” Daveluy and the American Academy of Dermatology offer these recommendations that people can follow to help ensure piercing success. Leave your jewelry in. Don’t remove your new piercing for six weeks or more, even at night. The piercing can close if you remove the jewelry too early. Keep the piercing clean. Always wash your hands so you can prevent infection of newly pierced areas. Use a mild, fragrance-free cleanser and water at least once a day. Thoroughly rinse away soap. Avoid getting water in your ear. Don’t clean your piercing with hydrogen peroxide or antibacterial soaps, which can damage healing skin. Apply petroleum jelly around each piercing to keep it moist and help with healing. Using petroleum jelly from a squeeze tube instead of a jar can help prevent transferring germs. Pay attention to what your piercing looks like. If it’s… read on > read on >
In 22 U.S. States, More Than a Third of Adults Are Now Obese
Obesity is on the rise across the United States. In 22 states, 35% of adults or more were obese last year, new data from the U.S. Centers for Disease Control and Prevention show. Just 10 years ago, there were no states that had obesity rates at or above 35%. “Our updated maps send a clear message that additional support for obesity prevention and treatment is an urgent priority,” said Dr. Karen Hacker, director of CDC’s National Center for Chronic Disease Prevention and Health Promotion. The 22 states with an adult obesity prevalence at or above 35% are Alabama, Arkansas, Delaware, Georgia, Indiana, Iowa, Kansas, Kentucky, Louisiana, Mississippi, Missouri, Nebraska, North Dakota, Ohio, Oklahoma, South Carolina, South Dakota, Tennessee, Texas, Virginia, West Virginia and Wisconsin. That’s up from 19 states in 2021. The CDC said the 2022 maps underscore the need to ensure that all people have access to healthy foods, safe places for physical activity and stigma-free obesity prevention and treatment programs. It also called for access to proven medications and weight-loss surgery. “Obesity is a disease caused by many factors, including eating patterns, physical activity levels, sleep routines, genetics and certain medications,” Hacker said in a CDC news release. “This means that there is no one size fits all approach. However, we know the key strategies that work include addressing the underlying social determinants… read on > read on >
Brain Trauma Could Help Trigger Heart Troubles
While the neurological impact of a traumatic brain injury (TBI) has long been studied, new research suggests TBIs are also hard on the heart. The research team took a closer look at connections between the two organs, finding that nervous system dysfunction, neuro-inflammation, changes in the brain-gut connection and post-injury health issues may increase risk of both cardiovascular and cognitive (brain) dysfunction for TBI survivors. Screening and preventive care may help offset these adverse outcomes, the researchers added. “Despite decades of extensive traumatic brain injury-focused research, surprisingly, there has been minimal progress in mitigating long-term outcomes and [death] following injuries. The cardiovascular effects of TBI may be a missing link in advancing our efforts to improve long-term quality of life and reducing [death] rates in TBI patients,” said first study author Dr. Saef Izzy, of the Stroke and Cerebrovascular Center of Brigham and Women’s Hospital, in Boston. “We have the opportunity to identify and improve targeted screening for high-risk populations, build preventative care strategies and improve outcomes for survivors of TBI,” he added in a hospital news release. TBI is a leading cause of long-term disability and premature death, especially among military personnel and those playing contact sports. While existing research has identified a strong link between TBI and various neurological conditions — including Alzheimer’s disease and dementia — much of its effect on other… read on > read on >
Today’s COVID Is Increasingly Looking Like a Cold or Flu
Symptoms of mild COVID-19 infection have shifted this season, and now are more akin to those of allergies and the common cold, doctors say. Many people with COVID-19 now are presenting with upper respiratory symptoms like runny nose, watery eyes and a sore throat, said Dr. Teresa Lovins, an independent family physician in Columbus, Ind. “A couple of patients told me ‘this seems like my allergies, but my allergy med isn’t working. And then I start feeling really, really tired and I just can’t get my energy up and about,’” Lovins recounted. “And I’m like, ‘yeah, we ought to test you for COVID,’ and more times than not it’s positive.” Fatigue also continues to plague COVID patients, according to Lovins and Dr. William Schaffner, a professor of infectious diseases at Vanderbilt University in Nashville, Tenn. “Fatigue for 24, 48 even 72 hours appears to be really quite common,” Schaffner said. “People just feel puny, as we say here in the South. They don’t all take to their bed, but there’s a fair amount of comment about people taking naps just because they feel wiped out.” Other well-established COVID-19 symptoms — deep cough, a loss of taste or smell, headache, fever — have become much less common or pronounced, Lovins and Schaffner said. “What I’m hearing from my clinical colleagues, there is indeed a great deal… read on > read on >
Gun Injuries Rise as Neighborhoods Gentrify
As working class neighborhoods gentrify, you’ll likely see rents rise, pricey restaurants move in — and maybe also a rise in gunshot wounds, researchers say. In U.S. neighborhoods that gentrified, gun injuries were 62% higher than they were in similar neighborhoods that hadn’t gone upscale, according to a new study. Overall firearm incidence was also 26% higher in these gentrifying neighborhoods compared to non-gentrifying neighborhoods. “To prevent firearm injuries in these communities, we must understand where the behavior is stemming from,” said study co-author Molly Jarman, of the Center for Surgery and Public Health at Brigham and Women’s Hospital in Boston. “It’s vital we begin to investigate the factors causing social disruption and housing displacement, such as gentrification, to develop and implement targeted interventions to prevent firearm injuries,” Jarman added in a hospital news release. Gentrification can improve certain conditions in poorer neighborhoods, the authors noted, but it can also lead to rising housing costs, which can displace the people who live there. That creates a high-stress environment, adding to known links to gun violence such as poverty, income inequality and minority status. “The solution is complicated, but our findings reveal an opportunity to identify communities that may be at increased risk of firearm violence,” said the study’s lead author, Dr. Sarabeth Spitzer, of Brigham’s department of surgery. “Hopefully, this allows support and resources, such… read on > read on >