Health/Fitness « Weekly Gravy

While joint reconstruction surgeries are fairly common, they may be anything but routine for people with sickle cell disease. Patients with the blood disorder who undergo total knee replacement are at a higher risk for complications than other patients, according to a new large-scale study. “SCD patients undergoing total knee replacement need a multidisciplinary approach and may be better served in specialized centers capable of caring for these complex medical patients,” said study author Dr. Senthil Sambandam, an assistant professor of orthopedic surgery at University of Texas Southwestern Medical Center in Dallas. “These patients have a higher risk of postoperative complications requiring the involvement of various specialists including nephrologists, pulmonologists and hematologists,” he explained in a UT Southwestern news release. Skeletal and arthritic issues are common among sickle cell patients. About 100,000 people in the United States have the disease. As the life expectancy for these patients has increased over the years, so has the proportion of those needing joint reconstruction. Researchers studied this using the National Inpatient Sample database to identify patients who underwent total knee replacement between 2016 and 2019. The team divided patients into two groups: those with sickle cell disease and those without. More than 558,000 patients had this surgery. Less than 1% — 493 — were known to have sickle cell disease. A greater proportion of them were younger, male… read on > read on >

Taking vitamins may drain your wallet without helping your health, yet a new government survey shows most American adults take them, as do about one-third of children. Researchers who were led by Suruchi Mishra, from the U.S. National Center for Health Statistics, found vitamin use was common from 2017 to March 2020, prior to the pandemic when vitamin use may have even increased. “It’s promoted as a natural product. It’s promoted as something that is different than what you’re going to get from your doctor, and the notion is that there’s no side effects because it’s all natural, and therefore it can only do good and can never do harm,” Dr. Paul Offit, a doctor at Children’s Hospital of Philadelphia, told CNN. “You can’t beat that,” added Offit, who is also the author of Do You Believe in Magic? Vitamins, Supplements, and All Things Natural: A Look Behind the Curtain. In reality, there is “insufficient evidence” to recommend for or against taking a multivitamin with folic acid, antioxidant combination vitamins or individual supplements for vitamins A, C or E to prevent cancer or heart disease in someone who is healthy but not pregnant, according to the U.S. Preventive Services Task Force (USPSTF). An exception may be vitamin D: Offit said it is thought to improve bone health by helping the body absorb calcium and phosphorous.… read on > read on >

It sounds like the stuff of a vampire novel, but for people with a group of rare genetic disorders, exposure to sunlight can cause excruciating pain. Now, an experimental medication is showing promise for helping them better tolerate the light of day. In an early clinical trial, researchers tested the drug for patients with either of two related conditions: erythropoietic protoporphyria (EPP) and X-linked protoporphyria (XLP). Both belong to a group of eight rare genetic disorders called porphyrias. Studies estimate that EPP and XLP affect one in every 75,000 to 200,000 white people. Both conditions arise from certain genetic abnormalities that cause a chemical called protoporphyrin to build up in the blood and the lining of the blood vessels. The trouble comes when a person with EPP or XLP goes into the sun: That light activates protoporphyrin in the blood vessels, which triggers inflammation, cell damage and severe pain. Both disorders usually become apparent in childhood — which, clearly, takes a toll on kids’ quality of life, said Dr. Robert Desnick, one of the researchers on the new trial. “They call themselves shadow-jumpers, because they have to run from one shady spot to another to avoid the sun,” said Desnick, a professor of genetics and genomic sciences at the Icahn School of Medicine at Mount Sinai, in New York City. Standard sunscreen offers no protection,… read on > read on >

Put out that cigarette for the health of your four-legged friend. When smokers search social media for anti-tobacco information, they tend to engage most with posts about the risk of secondhand smoke on their pets, a new study reveals. Posts with new information about harmful chemicals also receive high engagement, researchers found. “Our results show that people respond to messaging on how smoking negatively affects the lives of those they care about, including pets. Messages that are personally meaningful to smokers can help to generate positive behavioral changes among smokers,” said principal investigator Hong Xue, an associate professor of health administration at George Mason University in Fairfax, Va. “Anti-tobacco campaigns can use these findings to improve their campaigns, better engage the public, and more effectively promote reasons to stop smoking,” he said in a university news release. The researchers used machine learning and social media data to analyze factors that influence effective anti-smoking campaigns and user engagement. The study was led by Xue and GMU associate professor Gilbert Gimm. They described their work as the first large-scale social media data mining study that examined key anti-tobacco campaigns in the United States. Their research also found that large campaigns from government and nonprofit organizations had greater user engagement than smaller and local campaigns. Facebook users were much more likely to engage in messages with videos. About… read on > read on >

Four out of 10 people who have lingering health issues after COVID-19 infection can count bothersome sleep problems among them. About 41% of those with so-called long COVID have moderate to severe sleep issues, according to new research from the Cleveland Clinic in Ohio. Black patients are three times more likely to develop these sleep disturbances. “Sleep difficulties and fatigue are widely reported by people with long COVID, but little is known about the severity and factors associated with these symptoms,” said lead author Dr. Cinthya Pena Orbea, assistant professor of medicine at Cleveland Clinic’s Sleep Disorders Center. “Our findings not only emphasize the importance of identification of sleep disturbance in long COVID considering its impact on patients’ quality of life, daytime functioning and medical health status, but they also draw the attention to the persistent inequities seen throughout the COVID-19 pandemic,” Pena Orbea said in a clinic news release. Risk factors for these lingering sleep disturbances include race, hospitalization for COVID-19, and greater severity of anxiety and fatigue, she and her colleagues found. The researchers analyzed data collected from 962 long-COVID patients who were treated at Cleveland Clinic’s reCOVer Clinic between February 2021 and April 2022. The patients, all adults, completed sleep disturbance and fatigue questionnaires. Among the other findings: About 67% reported moderate to severe fatigue. About 22% reported severe fatigue. More than… read on > read on >

We know that stress can take a toll on the body, but many may not realize it can produce a rash. “Stress can increase the level of the hormone cortisol, increasing inflammation in your body, which can lead to hives, acne, eczema, and hair loss, among other symptoms,” dermatologist Dr. Elizabeth Farhat said in a recent article. Typically, hives are caused by an allergic reaction but can actually be triggered by stress. According to Scripps, you are more likely to develop a stress rash if you have experienced asthma, eczema, rosacea or allergies. Here is everything you need to know to manage a stress rash. What does stress rash look like? According to the Cleveland Clinic, hives can appear on your face, hands and neck. The hives will look like raised bumps that are reddish on lighter-colored skin. They can look like tiny pinpoints or welts and may develop into raised red clusters. Hives can change size and shape. When you press on the bumps, the skin will turn lighter in the center. When you have a stress rash on your face, you may also experience painful swelling of your lips, eyes and the inside of your throat. The rash can burn, itch and cause pain. Where does a stress rash appear? Hives can appear anywhere on the body. However, according to Scripps, when a… read on > read on >

Actor Hugh Jackman is offering a warning about sun damage and skin cancer after having two biopsies. Jackman was wearing a bandage on his nose in a video posted to his Twitter account. “I just went to my doctor… and she just saw little things — could be or could not be basal cell, in her opinion. She doesn’t know,” Jackman shared. “Summer is coming for those of us here in the Northern Hemisphere. Please wear sunscreen. It’s just not worth it no matter how much you want to tan. Trust me, trust me, trust me.” Basal cell carcinoma is common and not as potentially harmful as some other types of skin tumors, such as melanomas. It’s the type of skin cancer that President Joe Biden had removed after a recent physical. Jackman, 54, urged people to wear sunscreen. He previously was treated for basal cell carcinoma in 2013, 2014 and 2016, CBS News reported. Jackman reminded viewers that UV exposure in youth can leave a legacy of skin cancer decades later. “This is all stuff that happened 25 years ago and it is coming out now,” he said, pointing to the bandage on his nose. “Put some sunscreen on — you’ll still have an incredible time out there.” About 8 of every 10 skin cancers are basal cell carcinoma, according to the American Cancer… read on > read on >

Figuring out how stress affects your body can be a challenge, because the answer can depend on how stressed out you are, and for how long. For instance, recent research has shown that low-to-moderate stress levels may actually be good for your ability to learn and apply knowledge. High stress levels, on the other hand, can negatively impact your working memory. Likewise, short-term stress can impact your body differently than long-term stress. So, how does stress affect the body when it’s momentary versus chronic? Here, experts break down the most common physical, mental and emotional outcomes for both, and offer some tips on how to manage stress to help prevent long-term health issues. Short-term stress effects on the body Cleveland Clinic psychologist Dr. Susan Albers-Bowling noted that daily stressors such as forgetting to pay a bill or missing the bus to work tend to cause short-term, low-to-moderate stress on the body. “What happens in the body is that our muscles begin to tense, our heart begins to beat faster and more oxygen goes to our lungs, this is to help prepare for the stressor,” she said in a Cleveland Clinic article. “The good news is that often, stressors are minor. After the stressor passes, our body goes back to its normal resting state.” Dr. Suchita Shah, a University of Oxford undergraduate primary care tutor and… read on > read on >

(HealthDay News) – U.S. regulators inspecting a factory in India that has been linked to contaminated eyedrops have uncovered a laundry list of problems. An outbreak of eye infections involving products made at the factory stems from exposure to a highly drug-resistant bacteria known as Pseudomonas aeruginosa. So far, three people have died, while there have been eight reports of lost vision and dozens of infections. U.S. Food and Drug Administration inspectors were at Global Pharma Healthcare Ltd.’s factory from Feb. 20 through March 2, where they identified dirty equipment and clothing, as well as a lack of other safeguards. The FDA issued citations to the company after what appears to be their first-ever visit to the plant. “You used a manufacturing process that lacked assurance of product sterility,” the FDA said in the citation document. Artificial tears drops and ointment involved include those branded as EzriCare and Delsam Pharma. Those products have already been recalled. Among the many problems identified by the FDA were that surfaces touched by product packaging “were not cleaned, sanitized, decontaminated or sterilized.” A machine used to fill product into bottles had a “black, brown greasy deposit” on one of its parts, though company logs said the machine had been cleaned weeks before and not used since. Records about cleaning of filling machines and spaces also had gaps and discrepancies,… read on > read on >

(HealthDay News) – Pope Francis was back delivering Mass on Palm Sunday, just one day after he was released from the hospital following a three-day stay for bronchitis. Francis, 86, celebrated in St. Peter’s Square in Rome as about 60,000 people looked on, carrying palm fronds or olive tree branches, CBS News reported. The evidence of the pope’s recent illness could be heard as his voice became strained soon after starting. Francis first rode to the Mass holding a braided palm branch amid a long procession of cardinals, prelates and other Catholics, CBS News reported. The pope delivered a 15-minute homily, talking about homelessness and pain. Francis talked about moments when people feel “extreme pain, love that fails, or is rejected or betrayed.″ Francis cited “children who are rejected or aborted,” as well as broken marriages, “forms of social exclusion, injustice and oppression, [and] the solitude of sickness,” CBS News reported. He also talked about “young people who feel a great emptiness inside without anyone really listening to their cry of pain,” and who “find no other path but that of suicide.” And he spoke of a homeless German man who had died recently under the colonnade circling St. Peter’s Square. “I, too, need Jesus to caress me and be near to me,″ Francis said. “Entire peoples are exploited and abandoned; the poor live on… read on > read on >