Children who need to take oral steroids for chronic or life-threatening conditions can experience serious side effects, according to new research. Children with autoimmune disorders such as juvenile arthritis, psoriasis or inflammatory bowel disease are often prescribed a steroid to keep the illness under control. But the odds that a child might develop diabetes was nearly six times higher in children taking steroids than in those who don’t. The odds of high blood pressure was 19 times higher in those on steroids, and the likelihood of a blood clot was 16 times higher, the study found. The good news, however, is that these complications are all exceedingly rare. “These complications are serious but rare. They affect a very tiny proportion of children with steroids,” said study author Dr. Daniel Horton, an assistant professor of pediatrics and epidemiology at the Rutgers Center for Pharmacoepidemiology and Treatment Science in New Brunswick, N.J. Horton pointed out that doctors are aware of the many side effects related to steroids, but they also know how much good the drugs can do in certain situations, such as asthma or autoimmune conditions. “When I prescribe this medication, the benefits must outweigh the risks or I wouldn’t prescribe it. This study shows the kinds of complications that doctors need to look out for, particularly if a child receives high doses of an oral…  read on >

FRIDAY, Sept. 25, 2020 (Healthday News) — The U.S. coronavirus death toll passed 7 million on Friday, with California the hardest hit state so far in a pandemic that has crippled the country for more than six months. The United States has been averaging about 41,500 cases daily, down from the pandemic’s midsummer peak, but states in the Midwest and West are seeing case numbers climb, The New York Times reported. In California, the case count has now passed 800,000, the Times reported, but the figure does not capture the state’s current situation. Recently, California has been reporting a relatively low number of new cases daily, the newspaper said. It was less than a month ago that the United States reached 6 million cases, the Times reported. It took over three months for the country to record its first million cases. Despite those startling case counts, herd immunity is far from sight: The head of the U.S. Centers for Disease Control and Prevention told a Senate committee on Wednesday that 90% of Americans are still at risk of contracting the virus. “The preliminary results in the first round [of a very large, ongoing CDC study] show that a majority of our nation, more than 90% of the population, remains susceptible,” Dr. Robert Redfield testified. “A majority of Americans are still susceptible to this virus.” At…  read on >

HVAC repairman Brad Sissell shrugged off the acid-yellow air surrounding him and kept working, preparing a gas pipe for a new range going into a Salem, Ore., home. Less than a half-hour’s drive away, nearly 200,000 acres were burning in one of the major Oregon wildfires that has sent a full tenth of the state’s population fleeing for shelter. But it was a workday and so Sissell kept at his job, masked in the driveway with smoke wreathing his efforts. “We haven’t stopped,” Sissell, 35, said. “We’ve been working the whole time. I know they say the air’s not good for you. I think it’s going to suck for everybody.” The air quality index in Salem has been at the hazardous level since late last week, with people urged to stay indoors lest they risk their health. In fact, the West Coast cities of Portland, Seattle, San Francisco and Vancouver, B.C., have had the worst air quality of all major metropolitan areas in the world as wildfires burn unchecked, the Washington Post reported. Public health experts have warned people up and down the coast to remain indoors with the windows shut and their air conditioners running on recirculated air. The smoke from these wildfires contains fine particles and a toxic mix of chemicals that can irritate the lungs and inflame the airways, said Dr. Clayton…  read on >

Exercise is often recommended to combat stress and anxiety. But it might not be the solution to your pandemic-related worries, new research indicates. For the study, researchers analyzed data gathered from more than 900 pairs of identical and same-sex fraternal twins in Washington state during the early stages of the pandemic. While 42% said their physical activity levels fell, 27% said they rose. Another 31% reported no change. Those who said their physical activity levels had declined in the first two weeks after stay-at-home orders were issued reported higher levels of stress and anxiety, a finding that the researchers expected. But they were surprised that the same was true among many twins who boosted their physical activity levels, according to the study. “Certainly, people who don’t exercise know that there are associations with mental health outcomes, yet the ones that increased their exercise also reported increased anxiety and stress,” said study co-author Glen Duncan. He’s a professor at Washington State University College of Medicine, in Spokane. “It’s hard to know exactly what’s going on, but it could be that they are trying to use exercise as a means to counter that stress and anxiety they’re feeling because of COVID,” Duncan added in a university news release. The link between decreased physical activity and stress was confounded by genetic and environmental factors, the researchers noted. In…  read on >

WEDNESDAY, Sept. 16, 2020 (Healthday News) — A single infusion of an experimental drug dramatically lowers levels of coronavirus in the bodies of newly infected patients and cuts their chances of hospitalization, the drug’s maker reported Wednesday. Eli Lilly’s announcement did not include detailed data and hasn’t been peer-reviewed or published yet, The New York Times reported. The news comes from interim results of a trial sponsored by Eli Lilly and the U.S. National Institutes of Health. NIH officials would not comment on the announcement until they have seen more detailed data from the trial, the Times reported. How does the drug work its magic? It is a monoclonal antibody, a manmade copy of an antibody produced by a patient who recovered from COVID-19, the Times reported. Scientists around the world have high hopes that that monoclonal antibodies will prove to be powerful coronavirus treatments, but they come with a caveat: They are difficult to manufacture, and would take time to produce, the Times reported. In the trial, 452 newly diagnosed COVID patients received the monoclonal antibody or a placebo infusion. Some 1.7 percent of those who got the drug were hospitalized, compared with 6 percent of those who received a placebo — a 72 percent reduction in risk, Eli Lilly said. At the same time, blood levels of the coronavirus plummeted among those who…  read on >

Hearts donated by severely obese donors aren’t more risky for recipients than hearts from people who aren’t obese, a new study indicates. “These findings were somewhat surprising because the severely obese donors did tend to have more medical problems, such as diabetes and high blood pressure, than the non-obese donors,” said study author Dr. Leora Yarboro. She’s an associate professor of surgery at the University of Virginia, in Charlottesville. Her team analyzed the outcomes of 26,000 heart transplants in the United States from 2003 to 2017. About 3.5% of the donors were severely obese. There were no significant differences in short-term outcomes, one-year survival rates or long-term death rates between patients who received a heart from a severely obese donor and those who received a heart from a non-obese donor, the findings showed. The researchers also found that the percentage of heart transplants from donors with severe obesity rose from 2.2% in 2013 to 5.3% in 2017. Some of the obese donors did have other medical issues: 10% had diabetes versus 3% of non-obese donors, and 33% had high blood pressure versus 15% of donors who weren’t severely obese. The study was published Sept. 16 in the journal Circulation: Heart Failure. “This study shows that with careful selection, hearts from obese donors can be used without an increased risk to the recipient,” Yarboro said in…  read on >

THURSDAY, Sept. 17, 2020 (Healthday News) — The details of a plan to rapidly deliver a future coronavirus vaccine to Americans were unveiled by federal officials on Wednesday. Two of the key parts of the plan are to begin distributing a vaccine with 24 hours of any approval or emergency authorization and offering the vaccine for free, The New York Times reported. Officials from Operation Warp Speed — the multiagency effort to quickly vaccinate Americans against coronavirus — also said the timing of a vaccine was still unclear, the Times reported. That despite repeated statements from President Donald Trump that a shot could be ready before the election on Nov. 3. “We’re dealing in a world of great uncertainty. We don’t know the timing of when we’ll have a vaccine, we don’t know the quantities, we don’t know the efficacy of those vaccines,” Paul Mango, the deputy chief of staff for policy at the U.S. Department of Health and Human Services, told the Times. “This is a really quite extraordinary, logistically complex undertaking, and a lot of uncertainties right now. I think the message we want you to leave with is, we are prepared for all of those uncertainties.” Who will get the vaccine first? Initial distribution of a vaccine, possibly on an emergency basis, would to a limited group of high-priority people, such as…  read on >

As the coronavirus pandemic wears on, it’s clear that not everyone’s on the same page when it comes to preventing the risk of infection. Lots of people wear masks, try to maintain social distancing and avoid large gatherings. But plenty of others forgo a mask or wear it on their chin, go to busy bars and attend social gatherings, like weddings. Both sides think they’re right. And that’s led to friction and frustration among friends and families. How can you deal with these differences and keep your relationships intact? “This is a super-charged topic. Your beliefs about science are now injected with politics,” said Dr. Richard Catanzaro, chief of psychiatry at Northern Westchester Hospital in Mount Kisco, N.Y. “My fundamental approach to stuff like this is to be as direct as possible. Express the concerns that you have, and acknowledge that the other person might not agree, but explain it’s how you feel. For example, ask the person to wear a mask when you’re interacting with them. If they refuse, say, ‘Let’s talk virtually then,’” Catanzaro said. He added that the tone of the conversation hinges on how important the relationship is to you. “In a marriage or more permanent relationship, be more open with the person, and try to get them to see how their behavior is impacting you,” Catanzaro said. For more casual…  read on >

Smokers have a significantly raised risk of dying from a bleeding stroke, a new study warns. For the study, researchers analyzed data from over 16,000 same-sex twin pairs in Finland. The twins were born before 1958 and followed for about 42 years (between 1976 and 2018). During the follow-up, there were 120 deaths from subarachnoid hemorrhage (SAH). This is a type of bleeding stroke that occurs under the membrane that covers the brain. The median age at death was about 61. Compared to nonsmokers, the risk of fatal bleeding in the brain was three times higher among heavy and moderate smokers, and 2.8 times higher among light smokers. The findings were published Sept. 17 in the journal Stroke. “Our study provides further evidence about the link between smoking and bleeding in the brain,” co-author Ilari Rautalin said in a journal news release. Rautalin is a sixth-year medical and Ph.D. student at the University of Helsinki in Finland. Unlike previous research, this study found that high blood pressure, lower levels of physical activity and being female weren’t significant factors in the risk of a fatal brain bleed. The paper didn’t have data on nonfatal cases. And the researchers couldn’t assess the impact of previous smoking on these brain bleeds, because former smokers and never smokers were combined in the nonsmoking category. Still, “this long-term study in…  read on >

FRIDAY, Sept. 18, 2020 (Healthday News) — New details surfaced on Thursday on an unexplained neurological condition that struck a volunteer who was participating in AstraZeneca’s coronavirus vaccine trial. In an internal safety report obtained by CNN, company officials describe how a healthy 37-year-old woman “experienced confirmed transverse myelitis” after receiving her second dose of the vaccine. She was hospitalized on Sept. 5. The report describes how the patient had the first dose of the coronavirus vaccine in early June and was fine. She received her second dose in late August. While out running on Sept. 2, she “had a trip [not fall] with a jolt.” The report noted that she did not have any obvious injury to her spine when examined, according to CNN. The next day, the report said, she had difficulty walking, pain and weakness in her arms, pain and reduced sensation in her torso, a headache and reduced ability to use her hands. The report mentions twice that the woman was diagnosed with “confirmed” transverse myelitis, CNN reported. The condition, which can be triggered by viruses, causes inflammation in the spine. No other similar cases have been diagnosed among other study volunteers, according to the report. The woman’s neurologist also noted that the woman has started to feel better. The report, dated Sept. 10, was sent out to doctors who are…  read on >