Lifestyle « Weekly Gravy

Americans are making shifts in the supplements they take — fewer multivitamins and vitamins C and E, more fish oil and vitamin D. Many think of supplements as magic bullets, but studies don’t always support their supposed benefits. Some research is positive. Vitamin D is important for good health and very hard to get naturally from foods or, if you live in northern latitudes, from the sun. So you might need a supplement to meet daily needs. But first ask your doctor for a blood test to check your level and, if it’s low, whether it’s safe for you to sit in the sun twice a week for 15 minutes to allow your body to make D naturally. Significant studies show that it’s better to get certain nutrients directly from food. For instance, while foods high in omega-3 fatty acids, from walnuts to oily fish, have been linked to reduced risk of heart disease, the omega-3s in fish oil capsules may not deliver the same benefits. A 2018 study conducted by the U.S. Department of Agriculture found that many supplements — from vitamins A and D to the minerals selenium and chromium — contain higher amounts of the nutrient than stated on the label. That’s a concern because some good-for-you supplements can be harmful at high doses — even calcium, which is highly touted for… read on >

Eight of every 10 American households buys sodas and other sugary drinks each week, adding up to 2,000 calories per household per week, new research shows. To put that in perspective, 2,000 calories is equal to the recommended average caloric intake for an adult for an entire day. With the obesity epidemic continuing for Americans young and old, it’s still tough to get the message out that sugary drinks may prove lethal over time, one expert said. “It startles me how many patients of mine state that they ‘understand that soda is not good’ — however, they continue to drink for the pleasure principle,” said Sharon Zarabi. She directs the bariatric program at Lenox Hill Hospital in New York City. However, Zarabi added, “when you actually sit down and spend time explaining the contribution of excess calories, inflammatory markers, elevated triglycerides, addictive properties, weight gain, etc., you paint a different picture.” The new study was led by Stephen Onufrak, of the U.S. Centers for Disease Control and Prevention. The report — and a number of related studies — were to be presented Sunday at the annual meeting of the American Society for Nutrition, in Baltimore. In the soda consumption study, the CDC team looked at data from a government survey of the weekly grocery-buying habits of nearly 5,000 U.S. households, compiled in 2012. The findings… read on >

Extremely tiny bits of plastic: They’re in your food and drink, and even in the air around you. Now, new research calculates that the average American consumes more than 70,000 particles of these “microplastics” every year — and even that’s likely an underestimation, the scientists noted. Your microplastic intake might be even higher if you choose products that have more plastics involved in their processing or packaging — including bottled water, the research team said. Just how harmful is all this plastic in your body? That’s still unclear, said one expert unconnected to the new study. “It’s certainly concerning,” said Dr. Kenneth Spaeth, chief of occupational and environmental medicine at Northwell Health in Great Neck, N.Y. “I think the best we can say is perhaps there’s minimal harm here, but I think there is a possibility the harm could be extensive.” Other recent studies have shed light on the ubiquity of microplastics in people’s bodies. For example, one report out of Austria found that the average human stool sample contained at least 20 bits of microplastic. In another study, microplastic was found in 90% of samples of common table salt. However, it’s tough to accurately calculate the amount of plastic people consume, noted the lead author of the new study, Kieran Cox. That’s because the 26 studies used in the evidence review involved food sources… read on >

While taking vitamins may be fine for teens and young adults, supplements for weight loss, muscle-building and added energy may trigger severe medical problems, new research suggests. Regulations to keep these potentially harmful products out of the hands of young people are urgently needed, the study authors said. “The [U.S. Food and Drug Administration] has issued countless warnings about supplements sold for weight loss, muscle-building or sport performance, sexual function and energy, and we know these products are widely marketed to and used by young people,” said lead author Flora Or. She is a researcher with Harvard T.H. Chan School of Public Health’s Strategic Training Initiative for the Prevention of Eating Disorders, in Boston. For the study, Or’s team looked at FDA reports of medical problems associated with these supplements among people aged 25 and younger between January 2004 and April 2015. The investigators compared these reports with reports made for vitamins. In all, nearly 1,000 incidents were reported, of which 40% involved a severe medical problem, including hospitalization and death, the researchers said. Weight-loss, muscle-building and energy supplements were linked with an almost three times greater risk of severe medical problems compared with vitamins, the findings showed. In addition, supplements sold to boost sexual function and clean the colon were tied to about twice the risk of a medical problem. According to researcher S.… read on >

Adding a newer drug to standard hormone therapy lengthens the lives of younger women with advanced breast cancer, a new trial has found. The drug, called Kisqali (ribociclib), is already approved for treating such patients — based on earlier results showing it can delay the progression of their cancer. This is the first evidence it can also extend their lives, said senior researcher Dr. Debu Tripathy, chair of the breast medical oncology department at M.D. Anderson Cancer Center in Houston. After 3.5 years, 70% of patients given hormone therapy plus Kisqali were still alive. That compared with 46% of those given hormone therapy alone. That proof of a survival advantage hits “a pretty big milestone,” Tripathy said. And, he added, it argues for giving the drug as a “first-line or second-line” treatment to these patients. The findings were to be presented Tuesday at the American Society of Clinical Oncology annual meeting, in Chicago, and they will also be published in the New England Journal of Medicine. Kisqali is one of three newer drugs on the market called CDK4/6 inhibitors; the others are Verzenio (abemaciclib) and Ibrance (palbociclib). They work by blocking two proteins that help cancer cells grow and divide. Kisqali, taken as a tablet, was originally approved as a first-line treatment for postmenopausal women with advanced breast cancer that is hormone receptor-positive — which… read on >

Cutting-edge prostate cancer drugs that help extend life in the toughest cases might also be useful in fighting less aggressive tumors, two new clinical trials suggest. Two drugs that interfere with cancer’s ability to use testosterone for fuel, apalutamide (Erleada) and enzalutamide (Xtandi), are already approved for use against more advanced prostate tumors that don’t respond to regular therapy. But these trials show that the drugs also can improve survival and slow progression in prostate cancers that do respond to regular therapy, which typically involves medication that halts production of testosterone. Both clinical trials involved patients with prostate cancer that had spread to other parts of their body but who still responded to androgen-deprivation therapy. “We’re slowly starting to see a migration of drugs traditionally saved for advanced stages of disease, where we’re incorporating them into earlier stages of disease,” said Dr. Bobby Liaw, medical director of the Blavatnik Family Chelsea Medical Center at Mount Sinai, in New York City. He was not involved in the trials. Apalutamide combined with androgen-deprivation therapy caused a 33% reduction in overall risk of death, compared against patients who received a placebo alongside their androgen-deprivation therapy, said the lead researcher of that clinical trial, Dr. Kim Chi. Apalutamide also delayed progression of the cancer by 52%, and the length of time before patients required chemotherapy by 61%, said Chi,… read on >

More American women under age 65 have been diagnosed sooner and treated earlier for ovarian cancer since the Affordable Care Act went into effect in 2010, new research shows. And, more women received treatment within 30 days of diagnosis, improving their survival odds, the researchers said. For the study, the investigators analyzed data from the U.S. National Cancer Database. They compared nearly 36,000 women who were diagnosed and treated between 2004 and 2009, with more than 37,000 women diagnosed and treated between 2011 and 2014. Women in both groups were between 21 and 64 years of age. A similar number of seniors with ovarian cancer was used as a control group, because those women had access to Medicare and were much less likely to be uninsured before or after introduction of the Affordable Care Act, also known as Obamacare. Compared with the control group, there was a 1.7% gain in early-stage diagnosis and a 1.6% improvement in treatment within 30 days of diagnosis among younger women since 2010, the findings showed. The greatest gains were among women who got public insurance after the Affordable Care Act was introduced. These women had a 2.5% gain in early-stage diagnosis and timely treatment compared with the control group. The improvements were seen regardless of race, income or level of education. While a 1.7% improvement in early diagnosis may… read on >