People transitioning female to male face issues around future fertility. But new research suggests children in the future are a real possibility for these transgender men. Now, research shows that transgender men can remain fertile after even one year of testosterone treatment. It’s common for transgender men — those who were born female but who identify as male — to undergo testosterone therapy as a gender-affirming treatment. But some may later want children through their own pregnancy or via surrogate, the Israeli researchers explained. “Because the long-term effects of testosterone therapy on fertility are unknown, the current recommendation is to stop testosterone at least three months before fertility treatments,” said lead investigator Dr. Yona Greenman. She heads the Transgender Health Center at Tel Aviv-Sourasky Medical Center. The study included 52 transgender men, aged 17 to 40, who received testosterone therapy over 12 months. They had the expected increase in testosterone blood levels and decrease in estrogen, but their levels of anti-Mullerian hormone (AMH) remained in the normal range for fertility. AMH levels are used to appraise remaining eggs in the ovaries. Average levels in study participants decreased only slightly, suggesting their ovarian function was well-preserved, according to Greenman. Participants also showed no changes in the thickness of their uterine lining. A thick lining is crucial for embryo implantation and a successful pregnancy. The findings are…  read on >

Postpartum depression is a common and often devastating condition for new mothers, but the U.S. Food and Drug Administration on Tuesday approved the first drug to help combat it. The drug, Zulesso (brexanolone), is delivered via intravenous infusion. “Postpartum depression is a serious condition that, when severe, can be life-threatening,” noted the FDA’s Dr. Tiffany Farchione. “Women may experience thoughts about harming themselves or harming their child.” The condition “can also interfere with the maternal-infant bond,” added Farchione, who is acting director of the Division of Psychiatry Products in the agency’s Center for Drug Evaluation and Research. The FDA decision “marks the first time a drug has been specifically approved to treat postpartum depression, providing an important new treatment option,” she said in an agency statement. Psychiatrist Dr. Martha Wald agreed that women battling postpartum depression have long needed new options. “There is tremendous stigma around postpartum depression for women,” said Wald, a psychiatrist and psychoanalyst at Duke University, in Winston-Salem, N.C. “Many women experience great shame and feel inadequate as mothers if they struggle with depression at a time that is supposed to be joyous.” “Because of this stigma, many women choose to not seek help and endure great suffering in silence,” she said. “Postpartum depression affects 15 to 20 percent of the general population, and at least half of this group goes untreated.…  read on >

The jittery, delusional potheads of the old movie “Reefer Madness” have prompted eye rolls and chuckles over the years, but a new study argues that the cult classic might contain a kernel of truth. Smoking pot every day could increase your risk of a psychotic break with reality, particularly if you have access to high-potency strains of marijuana, European researchers report. As many as 1 in 5 newly diagnosed cases of psychosis might be linked to daily cannabis use, according to data gathered from 11 hospitals across Europe. People who used pot on a daily basis were three times more likely to have a first-time diagnosis of psychosis, and five times more likely if they used high-potency marijuana every day, researchers said. The new study “raises real concerns about the dangers posed by high-potency marijuana,” said Emily Feinstein, executive vice president and chief operating officer of the Center on Addiction. “Over the past decade, there has been an increase in the availability of high-concentration THC products, for both medical and recreational use,” said Feinstein, who wasn’t involved with the study. “While there may still be questions about the nature of the link between daily use of high-potency marijuana and psychotic disorder, this study suggests that we should be monitoring this issue very closely and taking steps to protect the public’s health.” But NORML Deputy Director…  read on >

Expectant moms often try to plan as many aspects of their upcoming delivery as they can. But one thing they might not consider is what type of pain relief they will choose if they need to have a C-section. Now, new research from the University of Texas suggests that while opioids can control pain, a combination of other painkillers could offer similar relief with fewer side effects and no risk of addiction. “Opioids do not need to be routinely prescribed for every woman,” said study author Dr. Jenifer Dinis. She is a clinical instructor in the department of obstetrics, gynecology and reproductive sciences at UT Health McGovern Medical School in Houston. “We can control pain effectively with ibuprofen and acetaminophen. For those who do need opioids, we don’t need to give out as much,” Dinis said. A big concern anytime opioids are used is the potential for addiction. As many as one in four people given a long-term prescription for opioids in primary care has reported struggling with addiction, according to the U.S. Centers for Disease Control and Prevention. Even if people don’t use the opioid prescriptions they’re given, family members or friends may end up using those drugs. In 2016, more than 11 million Americans said they had misused opioids during the past year, the CDC said. Approximately 130 Americans die every day due…  read on >

Expectant moms often try to plan as many aspects of their upcoming delivery as they can. But one thing they might not consider is what type of pain relief they will choose if they need to have a C-section. Now, new research from the University of Texas suggests that while opioids can control pain, a combination of other painkillers could offer similar relief with fewer side effects and no risk of addiction. “Opioids do not need to be routinely prescribed for every woman,” said study author Dr. Jenifer Dinis. She is a clinical instructor in the department of obstetrics, gynecology and reproductive sciences at UT Health McGovern Medical School in Houston. “We can control pain effectively with ibuprofen and acetaminophen. For those who do need opioids, we don’t need to give out as much,” Dinis said. A big concern anytime opioids are used is the potential for addiction. As many as one in four people given a long-term prescription for opioids in primary care has reported struggling with addiction, according to the U.S. Centers for Disease Control and Prevention. Even if people don’t use the opioid prescriptions they’re given, family members or friends may end up using those drugs. In 2016, more than 11 million Americans said they had misused opioids during the past year, the CDC said. Approximately 130 Americans die every day due…  read on >

Though they often dread social events, many introverts find they’re not as bad as feared and some have learned to fake an outgoing personality to get through the experience. In the business world, socializing is a key to success, said Erik Helzer, who led a team that examined the psychological implications for both introverts and extroverts. Helzer is an assistant professor of management and organization at the Johns Hopkins Carey Business School in Baltimore. “We’re told, ‘You ought to do this. It will help your career,’” he said in a university news release. “But that doesn’t mean we look forward to it. In fact, many people do not.” For the study, Helzer and colleagues asked 146 university students to spend 30 minutes interacting with strangers in a cocktail party environment. Many predicted the experience would be mentally draining and that they would feel worse, not better, after socializing. Not surprisingly, this was especially true for more introverted participants. When asked how they felt after socializing, more of the extroverts reported significant increases in positive feelings after socializing, which was not unexpected. But many of the introverts did, too, the study found. Overall, 40 percent of all participants predicted they would feel worse after socializing, but instead felt significantly better about it after it was over. Researchers also had participants rate each other’s social skills. Overall,…  read on >