
A common antiseizure drug used to treat epilepsy, migraines and bipolar disorder does not appear to increase the risk of autism for kids exposed to it in the womb, a new study says. Topiramate does not contribute to any risk of kids developing autism if their moms took it during pregnancy, researchers report in the New England Journal of Medicine. “Our findings provide needed clarity on the possible neurodevelopmental impacts of this commonly used drug,” lead researcher Dr. Sonia Hernández-Díaz, a professor of epidemiology at Harvard T.H. Chan School of Public Health, said in a news release. “While our primary analyses focused on mothers with epilepsy, the study has implications for moms and moms-to-be who live with other conditions treated by topiramate as well,” she added. Topiramate can treat epilepsy and migraine by calming overactive nerves in a person’s body, experts say. Another antiseizure drug, lamotrigine, also is safe for expectant mothers to take, researchers found. However, a third drug, valproate, does appear to increase risk of autism in kids, results show. The results for lamotrigine and valproate are consistent with earlier studies. Nearly 11% of kids exposed to valproate in the womb developed autism, and the risk increased as moms took larger doses of the drug, researchers report. Researchers also noted that while topiramate appears safe for a baby’s developing brains, it remains linked… read on > read on >