
The eyes may have it when it comes to the early diagnosis of autism in children, a new study finds. Researchers at the University of California, San Francisco (UCSF), have pinpointed a gene that affects how kids’ eyes react when they turn their heads. Typically, people use what’s called the vestibulo-ocular reflex to help their sight coordinate with their head movement. However, kids with autism appear to have a gene that puts this reflex into overdrive, and the change can be picked up on vision tests. That might help speed research into autism, said study co-author Kevin Bender, a professor in the UCSF Weill Institute for Neurosciences. “We can measure it in kids with autism who are non-verbal or can’t or don’t want to follow instructions,” Bender said in a university news release. “This could be a game-changer in both the clinic and the lab.” The significance of the variant in the eye-tracking gene, called SCN2A, was first spotted in mice. If you shake your head, your eyes still stay more or less “centered,” the researchers explained. But in mice with a particular form of the SCN2A gene, that wasn’t the case. Their vestibulo-ocular reflex got stuck. Would this aberration show up in children with autism? To find out, Bender’s group conducted a study involving 5 kids with autism and 11 of their siblings who… read on > read on >