Police seizures of “magic” mushrooms have more than tripled within the past five years, the U.S. National Institute on Drug Abuse reports. The total weight of psilocybin mushrooms seized by law enforcement increased from 498 pounds in 2017 to 1,861 pounds in 2022, according to a new report published Feb. 6 in the journal Drug and Alcohol Dependence. To put those seizures in perspective, a typical dried mushroom dose in clinical trials for psilocybin therapy runs between 2.5 grams (.08 ounces) to 6 grams (.2 ounces), according to a 2022 analysis in the journal Frontiers in Psychiatry. These seizures come in the midst of a surge in public interest regarding the use of psilocybin for therapy and recreation, researchers said. “While psilocybin is by no means the most dangerous drug, recreational use can come with unforeseen risks such as bad trips,” said lead researcher Joseph Palamar, an associate professor of epidemiology at the NYU Grossman School of Medicine.  “Research studies suggesting its effectiveness in treating mental health issues and extensive positive media coverage may lead some people to seek ‘shrooms’ outside of medical contexts,” Palamar added. “People who use psilocybin outside of medical supervision need to be educated about risks associated with use.” In 2018 and 2019, the U.S. Food and Drug Administration granted breakthrough therapy status to research using psilocybin as a treatment for…  read on >  read on >

The former ‘party drug’ ketamine has gotten some good press recently, with clinical trials suggesting it might be a powerful and fast-acting antidepressant. Now, one of the first “real-world” studies of ketamine against depression appears to support those findings. Researchers at the University of Michigan and the VA Ann Arbor Healthcare System say that almost half of 215 veterans who’d been suffering severe, treatment-resistant depression benefited from six weeks of ketamine infusions. “It’s not a silver bullet,” stressed study lead author Dr. Paul Pfeiffer. “But when we see these patients in our clinic, who have been through every treatment available and nothing has worked, to have even a quarter achieve a significant measurable response is very good. We routinely get thanked for making a difference in their lives.”  Pfeiffer led the study with Dr. Avinash Hosanagar. Both are faculty at the U-M Medical School department of psychiatry, and both treat patients in the VA Ann Arbor Healthcare System. The veterans involved in the new study were selected because they’d all tried and failed multiple treatments to curb their severe depression. Many had other mental health issues, such as post-traumatic stress disorder (PTSD), anxiety or a history of alcohol or drug abuse. The Michigan researchers had each of the patients receive ketamine infusions beginning in 2019 or the first nine months of 2020. Their outcomes were tracked…  read on >  read on >

They say money can’t buy happiness – and now a new study of Indigenous peoples around the world backs up that assertion. People living in small-scale societies on the fringes of the modern world lead lives as happy and satisfying as folks from wealthy, technologically advanced nations, researchers report Feb. 5 in the Proceedings of the National Academy of Sciences. “Surprisingly, many populations with very low monetary incomes report very high average levels of life satisfaction, with scores similar to those in wealthy countries,” said lead researcher Eric Galbraith, a professor with McGill University in Montreal. This runs counter to the notion that economic growth is a sure-fire way to increase the well-being of people in low-income countries, researchers noted. Global surveys have found that people in wealthier countries tend to report higher levels of life satisfaction than those in poorer countries, researchers said in background notes. However, these global polls tend to overlook people in societies where the exchange of money plays a minimal role in everyday life, and where livelihoods depend directly on nature, researchers said. For this study, researchers surveyed nearly 3,000 people from Indigenous or primitive communities at 19 sites around the world. Only 64% of the surveyed households had any cash, researchers said. And yet, their average life satisfaction scores were 6.8 on a 10-point scale across all communities, and…  read on >  read on >

Police killings of unarmed Black people are robbing the Black community of a precious commodity – sleep. Black adults across the United States suffer from sleep problems after they’re exposed to news of killings that occur during police encounters, a new study published Feb. 5 in the journal JAMA Internal Medicine finds. Specifically, Black adults experienced increases in short sleep, lasting fewer than seven hours a night, and very short sleep of less than six hours nightly. “These findings show that poor sleep health is another unfortunate byproduct of exposure to these tragic occurrences,” said lead researcher Dr. Atheendar Venkataramani, an associate professor of medical ethics and health policy at the University of Pennsylvania’s Perelman School of Medicine in Philadelphia. “Exposure of Black Americans to police violence — which disproportionately effects Black individuals — adversely impacts sleep health of these individuals, a critical keystone that further impacts our mental, physical and emotional well-being,” Venkataramani added in a university news release. For the study, researchers analyzed changes in sleep duration tracked by two separate federal surveys, and tied those changes to data on officer-involved killings around the nation. Results showed that about 46% of Black adults reported short sleep versus 33% of white respondents. For very short sleep, the numbers were 18.4% for Black adults and 10.4% for whites. Researchers speculated that awareness of the deaths…  read on >  read on >

If you’re over 65, you likely struggle sometimes to hear conversations clearly, but ignoring that may prompt even more serious health problems, experts say. If left unchecked, hearing loss can lead to social isolation and depression — two conditions known to raise dementia risk, said Dr. Leah Ross, a physician in the Division of Geriatric Medicine at Penn State Health’s Milton S. Hershey Medical Center. Hearing impairment is the third most common chronic condition faced by older adults, Ross said. Yet, only 20% of these folks have had a hearing test in the past five years, according to the American Speech-Language-Hearing Association. While more than half of adults acknowledge they struggle with hearing problems, only 11% have sought treatment. “A lot of times, people are suffering with hearing impairment for years before they even say anything to their doctors,” Ross noted in a Penn State news release. The good news? “It is a modifiable risk factor,” Ross said. “There’s something we can do about it.” What’s missed by not treating hearing loss is what it can trigger, Ross explained. In her practice, she often sees this familiar scenario: An older adult with hearing loss discovers his or her hearing has declined to the point where they have trouble understanding conversations. They start to skip social events and stay at home, as their world shrinks and…  read on >  read on >