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Time-restricted dieting may be a better way for people with type 2 diabetes to lose weight than counting calories, a new study suggests. Researchers found that people who only ate between noon and 8 p.m. each day lost more weight than those who reduced their calories by 25%. Both groups, however, had similar reductions in long-term blood sugar levels based on a test of hemoglobin A1C. The test shows blood sugar levels over the past three months. “It’s important to give people with type 2 diabetes more than one strategy to lose weight and decrease their HbA1C,” said lead researcher Krista Varady, a professor of nutrition at the University of Illinois, Chicago. “Some people find it difficult to count calories. Others don’t have weekly or monthly support and they need a dietary pattern that is simple to follow, such as watching the clock,” Varady added. In the United States, about 1 in 10 U.S. residents has diabetes, and that number is rising, the researchers said. It’s crucial to find more ways to control weight and blood sugar levels for these patients. While the study represents a “proof of concept” showing that time-restricted eating is safe for those with type 2 diabetes, Varady said people with diabetes should consult their doctor before starting this sort of diet. Also, “some medications for type 2 diabetes will lower… read on > read on >

Federal regulators are warning consumers to stop using eyedrops and gels from several major brands after finding unsanitary conditions in a manufacturing plant. Twenty-six eye care products are part of the alert. Contaminated products have the potential to cause eye infection and blindness because drugs applied to the eye can bypass some of the body’s defenses. Those concerning the U.S. Food and Drug Administration are branded CVS Health, Leader (Cardinal Health), Rugby (Cardinal Health), Rite Aid, Target Up & Up and Velocity Pharma. The FDA urged the manufacturer to recall all lots of these products. CVS, Rite Aid and Target are pulling products from shelves and websites. Although there were no reports of infection, bacterial tests were positive in critical drug product areas of the plant. The FDA’s list of eye products to avoid is here. Patients and providers should report any issues to the FDA. Consumers should discard products involved in the recall at a drug take-back site. They can also check the FDA’s flush list to see if they can be safely discarded at home, the New York Times reported. Certain products — those branded Leader, Rugby and Velocity — may still be available for purchase in stores and online. Don’t buy them, the FDA advised. Rite Aid is removing “applicable Rite Aid branded products” from store shelves, a spokeswoman said. CVS “immediately… read on > read on >

MONDAY, Oct. 30, 2023 (HealthDay News) — Patients with sickle cell disease may soon have two new treatments to try. On Tuesday, a U.S. Food and Drug Administration advisory committee will weigh the merits of a new gene therapy for the painful, inherited condition, which typically strikes Black people. The agency is expected to make a decision on that therapy in early December, and it also plans to decide on a second new treatment before year’s end, the Associated Press reported. The treatment being reviewed Tuesday is based on CRISPR technology, a gene-editing tool. The inventors of that tool won the Nobel Prize in 2020 for their work, the AP reported. A one-time treatment, “exa-cel” is made by Vertex Pharmaceuticals and CRISPR Therapeutics, and it permanently changes DNA in a patient’s blood cells. How does it work? Stem cells are removed from a patient’s blood, and then CRISPR knocks out a gene that triggers the development of defective, crescent-shaped blood cells. Meanwhile, medicine kills off flawed blood-producing cells in patients, who are then given back their own altered stem cells. “Anything that can help relieve somebody with this condition of the pain and the multiple health complications is amazing,” Dr. Allison King, a professor at Washington University School of Medicine in St. Louis, told the AP. “It’s horribly painful. Some people will say it’s like being stabbed… read on > read on >

As sweltering summer days become more common, the number of Americans who die of heat-related heart problems or strokes could soar over the next few decades, a new study projects. The study — published Oct. 30 in the journal Circulation — estimates that by mid-century the United States will see those preventable deaths more than triple if greenhouse gas emissions are allowed to rise unchecked. Older adults and Black Americans are expected to be hardest-hit — a prospect that would widen the racial disparities in heart disease that already exist. That’s the bad news. The more hopeful finding is that some of those heat-related deaths could be avoided by implementing current proposals on cutting emissions. “Our study suggests there could be a benefit from reducing emissions, and within a short time frame,” said lead researcher Dr. Sameed Khatana, a cardiologist and assistant professor of medicine at the University of Pennsylvania. Experts have long known that heat waves often trigger a spike in strokes, heart attacks and other cardiovascular complications — typically among people with preexisting risk factors. That’s because the heart and blood vessels (cardiovascular system) are central players in regulating body temperature, Khatana said. When the body overheats, the heart works harder, pumping blood to the periphery of the body to release heat through sweat. And for vulnerable people, that stress can be too… read on > read on >

MONDAY, Oct. 30, 2023 (HealthDay News) – Matthew Perry, one of the stars of the beloved television sitcom “Friends,” died on Saturday. Perry, 54, was best known for his portrayal of Chandler Bing in the long-running show, but he also starred in many other roles. Capt. Scot Williams, of the Los Angeles Police Department’s Robbery-Homicide division, confirmed Perry’s death, the New York Times reported. Investigators saw no sign of foul play, but the cause of death has not been determined. The actor had spoken openly about his history of addiction in interviews and in the memoir he released in 2022, called “Friends, Lovers and the Big Terrible Thing.” In 1997, he went to rehab for an addiction to pain medication, according to news reports at the time. He was hospitalized for pancreatitis in 2000, an inflammation that can be caused by alcohol and drug abuse, the Times reported. Then in 2018, he developed pneumonia, suffered an exploded colon, spent time on life support, was in a coma for two weeks, had a colostomy bag for nine months and went through several stomach surgeries, all of which were tied to his addiction, the Times reported. He was newly sober two years ago. Perry had said he had spent more than half his life in treatment centers or sober living facilities. “I was a guy who wanted… read on > read on >

Kids with a genetic risk for autism spectrum disorder (ASD) are likely to spend hours a day glued to their screens, but researchers say it doesn’t mean screen time causes ASD. The investigators also found that children with attention-deficit/hyperactivity disorder (ADHD) gradually increased their screen time as they got older, even if they started out with low levels of initial screen use. “While long periods of screen time in childhood have been suggested to be a cause of ASD/ADHD, the results of this study suggest that some people may have a genetic disposition to use screens because of ASD,” said lead researcher Dr. Nagahide Takahashi. He is an associate professor of medicine at Nagoya University in Japan. “Screen time may be an early sign of ASD, rather than a cause, as children with ASD are often more attracted to objects than people,” he added in a university news release. “Physicians should know that it is not fair to conclude that prolonged screen time is a risk factor for the development of ASD,” Takahashi explained. Most people are spending more time on digital devices, including smartphones, computers, television and video game systems. The researchers said that’s especially true for kids with neurodevelopmental disorders. Joining with colleagues from Hamamatsu University, Takahashi’s team examined 6.5 million differences in the DNA of 437 children to determine genetic susceptibility to… read on > read on >

Millions of people spend hours looking at screens every day, straining their eyes. An ophthalmologist at Baylor College of Medicine in Houston offers some tips for easing both eye strain and headaches. “We focus on one object, especially an object that’s up close, like a computer screen or phone, for prolonged periods of time, and we don’t give our eye muscles time to rest,” said Dr. Masih Ahmed, an assistant professor of ophthalmology at Baylor. “If you don’t give your muscles enough time to rest, that can cause some tension of those muscles,” Ahmed explained. Dry eye can also cause eye strain, as you subconsciously blink less when reading, watching TV or working on the computer. Follow the 20-20-20 rule when working in front of a screen, Ahmed suggested. Take a 20-second break every 20 minutes to focus on something 20 feet away to give your eyes a rest. And use artificial tears if you have dry eyes. Prolonged eyestrain can give you a headache. If you wear corrective lenses, make sure you have the proper prescription, he advised. If you have an astigmatism, you won’t see as sharply. This might require more focus and energy, leading to eye strain. “You might squint more trying to get that pinhole effect for things to look clearer. Astigmatism can also make things look distorted in shape if… read on > read on >

You might be talking to a real person while on Zoom, but it’s just not the same to your brain as a face-to-face conversation. New research using sophisticated imaging tools found that the brain activity of people engaged in conversation looks different from that of two people conversing on Zoom. “In this study we find that the social systems of the human brain are more active during real live in-person encounters than on Zoom,” said senior author Joy Hirsch. She is a professor of psychiatry, comparative medicine and neuroscience at Yale University in New Haven, Conn. “Zoom appears to be an impoverished social communication system relative to in-person conditions,” she explained in a Yale news release. Zoom, of course, is a popular videoconferencing platform. Most previous research using imaging tools to track brain activity involved single individuals, rather than pairs in natural settings. The researchers noted that human brains are finely tuned to process facial cues during in-person encounters. In this study, which recorded neural system responses in the two types of conversations, increased neural signaling among participants in face-to-face conversations was associated with increased gaze time and wider pupils. This suggested increased arousal in the two brains. Participants in in-person interactions also had increased brain wave activity characteristic of enhanced face-processing ability, the study authors said. The investigators also found more coordinated neural activity… read on > read on >

Federal regulators have sent warning letters to two companies for illegally selling probiotic products for use in preterm infants. The U.S. Food and Drug Administration also sent a letter to health care providers warning of the risks. Probiotic products contain live organisms such as bacteria or yeast. They are commonly found in dietary supplements. These products may be dangerous for preterm infants and are being illegally sold to treat or prevent diseases in preemies in hospitals, such as necrotizing enterocolitis. Those young babies who are given a probiotic product are at risk of invasive, potentially fatal disease, or infection, caused by the bacteria or yeast in the probiotics, the FDA said. Certain products have contributed to invasive disease in hospitalized babies, including one death this year. They have been linked to more than two dozen other reported adverse events nationwide since 2018, according to the FDA. “Adverse events in any infant following the use of a probiotic are a concern to the FDA. We especially want to make clear that products containing live microorganisms may present serious risks to preterm infants in hospital settings,” Dr. Peter Marks, director of the FDA’s Center for Biologics Evaluation and Research, said in an agency news release. “With today’s message, we want to warn parents, caregivers and health care providers that if these products are used for the prevention… read on > read on >

Fighting climate change could come down to choosing chicken for your burrito or using soy milk for coffee creamer, a new study suggests. Making simple substitutions to an everyday diet can reduce the average American’s food-based carbon footprint by more than 35%, according to an article published online Oct. 26 in the journal Nature Food. “What we’re looking at here is a small changes approach. What happens if somebody just changes one thing in their diet?” said senior researcher Diego Rose, nutrition program director at Tulane University School of Public Health and Tropical Medicine in New Orleans. “What we found was that if you just made one change — if everybody that was eating a high-carbon footprint food in those categories just made one change on a given day — that you could really lower the overall carbon footprint,” Rose continued. What’s more, these substitutions also tended to improve the quality of a person’s diet, the researchers noted. A person might scoff at the thought of their bacon cheeseburger contributing to global climate catastrophe, but they would be wrong, Rose said. “What a lot of people don’t realize is that human food systems globally account for a third of greenhouse gas emissions,” he said. To assess how small substitutions might help the climate, Rose’s team analyzed diet data from more than 7,700 adults and children… read on > read on >

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All Sauce from Weekly Gravy:

Fasting Diets Beat Low-Cal Regimens for Folks With Diabetes

FDA Warns Eyedrops From Major Brands May Cause Infection

FDA Advisors to Weigh New Gene Therapy for Sickle Cell Anemia

U.S. Heat-Related Heart Deaths Will Multiply With Warming Temperatures

‘Friends’ Star Matthew Perry Dead at 54

Lots of Screen Time Could Be Early Sign of ADHD, Autism

Staring at Screens Can Cause Eye Strain. Here’s Tips to Prevent That

This is Your Brain on Zoom

FDA Issues Warning on Dangers of Probiotic Products for Preemie Babies

Even Small Dietary Changes Bring Big Benefit to the Planet