
Grandma knew it all along: Certain places on the body are “hot spots” for unhealthy microbes. That notion — which the authors of a new study dubbed “the grandma hypothesis,” after grandma’s admonitions to clean behind the ears — was tested by students in a genomics course at George Washington (GW) University in Washington, D.C. The investigators proved what grandma knew all along: Skin behind the ears and between the toes can harbor unhealthy microbes. The collection of microbes living on and in the body is known the microbiome. It has a role in human health. The skin’s microbiome varies across dry, moist and oily areas. So students set out to test the hypothesis. Keith Crandall, director of the Computational Biology Institute at GW, recalled his own grandmother always telling the kids in his family to “scrub behind the ears, between the toes and in the belly button.” Crandall thought these hot spots were normally washed less often compared to the skin on the arms or legs and might harbor different types of bacteria. Together with Marcos Pérez-Losada, an associate professor of biostatistics and bioinformatics, he designed this genomics course. In it, 129 graduate and undergraduate students were taught to collect their own data by swabbing certain moist and oily hot spots, behind the ears, between the toes and in the naval. They swabbed calves… read on > read on >