All Sauce from Weekly Gravy:

Can you literally step away from depression? A new global review of data found that “increasing the number of daily steps, even at modest levels, was associated with a reduction in depressive symptoms.” The Spanish study found that up to a level of about 10,000 steps per day, the odds for depression decline as daily step levels rise. The findings were published Dec. 16 in the journal JAMA Network Open. Researchers led by Estela Jimenez-Lopez, of the University of Castile-La Mancha, noted there’s already solid evidence that exercise of any kind is a natural antidepressant. But what about something as easy as walking? To find out, they looked at data from high-quality studies on daily step counts and their links to mental health. In total, the new review covered 33 studies involving a total of more than 96,000 adults worldwide. Studies included people who used fitness-tracker devices to calculate their daily steps. Compared to a baseline of 5,000 steps taken per day, folks who took even 1,000 more steps daily saw a 9% drop in their odds for developing depression, the researchers found. Those benefits quickly mounted up: Compared to folks walking 5,000 steps per day or less, those who walked 7,000 steps/day had a 31% lower odds for depression, the study found. “In addition, counts above 7,500 steps/d were associated with a 43% lower…  read on >  read on >

Do parents use Santa Claus to help guide kids to better behavior? It happens often, a new poll shows. One-quarter of parents of kids ages 3 to 5 said they’ve threatened misbehaving kids with no Santa or gifts if they don’t shape up, according to results from the University of Michigan Health C.S. Mott Children’s Hospital National Poll on Children’s Health. Many parents also reported threatening to leave a Christmas activity, taking away toys or denying dessert to get their kids to behave, the poll found. What’s more, nearly half of parents polled have resorted to bribes to get better behavior from kids. Unfortunately, these aren’t likely to be winning strategies, Mott pediatrician Dr. Susan Woolford said in a hospital news release. “Discipline helps young children learn what behaviors are safe and appropriate and can play a crucial role in helping them learn the difference between right and wrong,” Woolford said. “Empty threats, however, undermine trust and credibility and aren’t usually effective,” Woolford added. “Positive reinforcement and consistent discipline are more likely to shape long-term behavior.” About half of parents rated themselves as very consistent in disciplining their child, based on poll responses from 725 parents with at least one child between the ages of 1 and 5. But it’s not easy — nearly a quarter of parents said they become overly irritated by their…  read on >  read on >

Close friendships are incredibly important to the mental health of middle-aged folks and seniors, a new study finds. Older adults with worse mental or physical health were twice as likely to say they don’t have any close friends, according to results from the University of Michigan National Poll on Healthy Aging. “With growing understanding of the importance of social connection for older adults, it’s important to explore the relationship between friendship and health, and identify those who might benefit most from efforts to support more interaction,” said investigator Sarah Patterson, a research assistant professor with the University of Michigan Institute for Social Research. Overall, 90% of people 50 and older said they have at least one close friend, and 75% say they have enough close friends, poll results showed. But about 20% of those with fair to poor mental health and 18% of those in fair or poor physical health say they have no close friends, researchers found. Another 47% of those in fair or poor mental health said they don’t have enough close friends, results show. The poll also found that 79% of those with at least once close friend felt that they could turn to them for emotional support, and 50% had a friend who encouraged them to make healthier choices like eating better or getting more exercise.  In addition, 35% said a…  read on >  read on >

The U.S. obesity rate declined for the first time in a decade last year, coinciding with the rise of GLP-1 weight-loss meds, a new study finds. Data on almost 17 million adults nationwide showed the obesity rate — which has been rising for years — fell from 46.2% of adults in 2021 to 45.6% in 2023, Harvard University researchers report. Obesity was defined as having a body mass index (BMI) of 30 or above. At the same time, the use of GLP-1 medications like Wegovy and Zepbound has surged, although the researchers said it’s not possible to confirm a cause-and-effect relationship between the trends. Still, they noted that, “The most notable decrease [in obesity] was in the South, which had the highest observed…dispensing rate,” for GLP-1 medications. The study was led by Benjamin Rader, an assistant professor of anesthesia at Harvard Medical School, and published Dec. 13 in the journal JAMA Health Forum. As Rader’s team noted, “the prevalence of obesity in the U.S. has increased for several decades. Some long-term forecasts estimate that this upward trajectory will continue, while others forecast a plateau.” The introduction of GLP-1 meds like semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro, Zepbound) into the marketplace has been a perhaps unexpected new factor in recent years, however. Sales of the injected medications have soared, and the results in terms of weight…  read on >  read on >

Have you been boozing more often than usual? A new blood test might be able to tell if you’re damaging your liver from too many beers, margaritas or belts of scotch, researchers report. A blood-borne byproduct of alcohol consumption called phosphatidylethanol (PEth) can give doctors a fair idea of how much liver scarring has occurred due to drinking, as reported recently in the American Journal of Gastroenterology. Blood testing for PEth would help doctors understand patients’ drinking habits better than just asking how much they’ve been drinking. “This is a more direct way to measure the harm that alcohol is causing in the body than asking patients,” said senior researcher Judy Hahn, a professor in the University of California, San Francisco’s (UCSF) Division of HIV, Infectious Diseases and Global Medicine. “We don’t ask someone how much fatty food they eat. We measure their cholesterol,” Hahn noted in a university news release. “We don’t ask people how much they think they weigh. We weigh them.” The body produces PEth as it processes alcohol, and previous studies have shown that PEth blood concentrations accurately reflect the amount someone imbibed, researchers said in background notes. Heavy drinking is widespread in the United States and that increased even more during the pandemic. About 24% of U.S. adults binge drink, and more than 6% are heavy drinkers, according to data…  read on >  read on >

The same technology behind COVID vaccines might be able to protect both the mother and child from a dangerous complication of pregnancy. A new mouse study published Dec. 11 in the journal Nature shows that injections based on that vaccine platform reduced the risk of preeclampsia in lab mice. Preeclampsia is persistent high blood pressure that occurs during pregnancy or after giving birth. It can threaten the life of both the mother and baby, or leave the mom with severe organ damage. The experimental injection “was able to deliver an mRNA therapeutic that reduced maternal blood pressure through the end of gestation and improved fetal health and blood circulation in the placenta,” said researcher Kelsey Swingle, a doctoral student in bioengineering at the University of Pennsylvania School of Engineering and Applied Science. “Additionally, at birth we saw an increase in litter weight of the pups, which indicates a healthy mom and healthy babies.” Preeclampsia affects 3% to 5% of pregnancies, researchers said in background notes. There’s no cure for the condition; instead, women take blood pressure medication or stay on bed rest. Preeclampsia arises due to insufficient blood flow to the placenta, which causes a mom’s blood pressure to rise while restricting blood flow to the fetus. Researchers figured that a drug designed to get into the placenta despite the restricted blood flow might help…  read on >  read on >

Caregiving for children or sick loved ones can be very stressful. so much so it can affect your heart health, new research shows. High caregiving stress increases risk of high blood pressure by nearly 40% among Black women ages 21 to 44, according to results published recently in the journal Hypertension. “Our analysis suggests that caregiver strain as a source of chronic stress may significantly contribute to the development of hypertension, a major risk factor for cardiovascular disease, among reproductive-age Black women,” said lead researcher Milla Arabadjian, an assistant professor at NYU Grossman Long Island School of Medicine. For the study, researchers analyzed data from the Jackson Heath Study, a long-term research project following the health of more than 5,300 Black adults in Mississippi. Participants had their blood pressure monitored, and were asked about caregiving stress as part of a health questionnaire. Nearly 44% of the young Black women in the study developed high blood pressure during a follow-up period of more than seven years, results showed. But caregiving stress made a difference: About 52% of the women who reported moderate or high caregiving stress developed high blood pressure, compared with about 41% of those with low caregiving stress or none, researchers found. “Given the high lifetime risk of cardiovascular disease, especially among reproductive-age Black women, we need to better identify the root causes contributing…  read on >  read on >

The ancient Japanese practice of reiki “energy healing” might help some cancer patients deal with the pain that can come with infusion therapies, new research shows. “Outpatients receiving reiki during infusion reported clinically significant improvements in all symptoms, high levels of satisfaction and a qualitatively positive healing experience,” reported a team led by Natalie Dyer, of Connor Whole Health at the University Hospitals of Cleveland. Her team published its findings recently in the Journal of Pain and Symptom Management. The Cleveland Clinic notes that reiki “has roots in ancient Japanese healing practices and is considered a form of energy healing. It stems from the Japanese words ‘rei,’ meaning universal, and ‘ki,’ meaning vital life force energy.” The theory behind reiki is that people all have a life force and a reiki master (a practitioner trained in reiki) can channel the “universal life force energy” to you by either lightly touching you with their hands or hovering their hands above you, “channeling” energy in healthy ways. Does reiki work beyond a possible placebo effect? That still “up for debate,” the Cleveland Clinic said, and probably will be for some time to come. In the new study, Dyer and colleagues tracked outcomes for 268 cancer patients who were receiving infusion treatments such as chemotherapy on an outpatient basis. These treatments can come with painful side effects, such…  read on >  read on >

In what appears to be a last-ditch effort to limit the harms of smoking before its term ends, the Biden administration has proposed a rule that would significantly lower the amount of nicotine in tobacco products. The agency’s efforts to counter the dangers of the addictive chemical stretch back to 2018, when it first proposed the idea. Then, FDA Commissioner Dr. Robert Califf went even further in 2022 and announced that the agency was developing a rule that would require tobacco companies to reduce the amount of nicotine in cigarettes. The next step in that effort took place Tuesday when the FDA finally submitted its refined proposal to the Office of Management and Budget. “A proposed product standard to establish a maximum nicotine level to reduce the addictiveness of cigarettes and certain combusted tobacco products, when finalized, would be among the most impactful population-level actions in the history of U.S. tobacco product regulation,” the FDA told CNN on Wednesday. The latest action was welcomed by health experts. “Once finalized, this rule could be a game-changer in our nation’s efforts to eliminate tobacco use,” Harold Wimmer, president and CEO of the American Lung Association, told CNN. “Making tobacco products non-addictive would dramatically reduce the number of young people who become hooked when they are experimenting.” “To fully address the toll of tobacco on our nation’s health and across all…  read on >  read on >

Keeping your blood pressure in check is important for more than just heart health — it can also keep your brain sharp as you age. A new study published Dec. 11 in the journal Neurology shows that seniors whose blood pressure spikes and drops over time might be more likely to suffer a decline in their thinking and memory skills. “These results suggest that fluctuation in blood pressure is a risk factor for cognitive problems beyond the negative effects of high blood pressure itself,” said researcher Dr. Anisa Dhana, a postdoctoral researcher with Rush University in Chicago. For the study, researchers recruited nearly 4,800 people with an average age of 71. Participants had their blood pressure tested regularly over three years, and completed thinking and memory skills tests at the beginning and end of the 10-year study. Overall, participants had an average blood pressure of 138/78. High blood pressure is defined as 130/80 or higher. It’s important to note, however, that this study was observational and could not draw a direct cause-and-effect link between blood pressure and brain health, Dhana noted. Results showed that people whose blood pressure fluctuated the most experienced nearly three additional years of brain aging, based on cognitive tests. On the other hand, people taking blood pressure medications showed no difference in scores on thinking tests by the end of the…  read on >  read on >