All Sauce from Weekly Gravy:

The harmful effects of obesity on the heart can’t be undone by exercise, and it’s not possible to be “fat but healthy,” Spanish researchers warn. “Exercise does not seem to compensate for the negative effects of excess weight,” said study author Alejandro Lucia, a professor of exercise physiology at European University in Madrid. The study findings “refute the notion that a physically active lifestyle can completely negate the deleterious effects of overweight and obesity,” he said. Lucia and his colleagues analyzed data from nearly 528,000 working adults in Spain. The participants’ average age was 42 and close to 7 out of 10 were men. About 42% of these adults were normal weight; 41% were overweight, and 18% were obese. Most were inactive (63.5%); 12.3% got some but not enough exercise, and 24.2% were regularly active. About 30% of participants had high cholesterol; 15% had high blood pressure, and 3% had diabetes. No matter how active they were, however, overweight and obese people had a higher risk of heart disease than those whose weight was normal, according to the study, published Jan. 22 in the European Journal of Preventive Cardiology. Compared to active people of normal weight, active obese people were about twice as likely to have high cholesterol, four times more likely to have diabetes, and five times more likely to have high blood pressure.…  read on >  read on >

As worldwide obesity rates continue to soar, new research shows that growing numbers of people are developing a potentially blinding type of weight-linked headache that was once considered rare. Though the study was conducted in Wales, one U.S. expert said the same surge in these headaches is likely happening in this country and elsewhere, but he cautioned that just because someone is obese and has headaches doesn’t mean he or she have this rare headache, known as idiopathic intracranial hypertension (IIH). “Obese individuals are at greater risk for more frequent migraine, too,” noted Dr. Brian Grosberg, director of the Hartford HealthCare Headache Center in Connecticut. In the study, IIH rates increased sixfold in Wales between 2003 and 2017 — from 12 per 100,000 people to 76 per 100,000 people. During the same 15-year span, obesity rates in Wales rose from 29% of the population to 40%. “The considerable increase in IIH incidence” has several causes, but is likely “predominately due to rising obesity rates,” said study author William Owen Pickrell, a consultant neurologist at Swansea University. “The worldwide prevalence of obesity nearly tripled between 1975 and 2016, and therefore, these results also have global relevance.” His findings were published in the Jan. 20 issue of Neurology. IIH is a type of headache that occurs when the fluid around your brain and spinal cord builds up…  read on >  read on >

Stem cell transplants may have long-lasting benefits for some people with aggressive cases of multiple sclerosis, a new study suggests. Italian researchers found that among 210 multiple sclerosis (MS) patients who received a stem cell transplant — with cells from their own blood — two-thirds saw no worsening in their disability 10 years out. That included 71% of patients with relapsing-remitting MS, the most common form of the disease. The sustained level of effectiveness is “pretty dramatic,” said Bruce Bebo, executive vice-president of research programs for the National Multiple Sclerosis Society. At the same time, there are important caveats, said Bebo, who was not involved in the study. For one, the patients were not part of a clinical trial that directly tested stem cell transplants against standard MS medications. They all underwent transplants at various Italian medical centers between 1997 and 2019. So it’s unclear exactly how such transplants measure up against the most effective MS drugs now available. Beyond that, Bebo said there are ongoing questions about which MS patients are the best candidates for a transplant, and the optimal timing for it. Those are no small matters, since a stem cell transplant is a major undertaking, he pointed out. “And it’s not reversible, like a medication you can change when it’s not working,” Bebo said. MS is a neurological disorder caused by a…  read on >  read on >

Millionaires, rejoice! It turns out that money can, in fact, buy happiness. And a new study suggests more is better, with well-being rising as earnings grow. “Having more money gives people a greater sense of control over life,” said study author Matthew Killingsworth. The finding stems from more than 1.7 million real-time reports of well-being from more than 33,000 U.S. adults. They were prompted by their cellphones to answer the question “How do you feel right now?” at random times during their waking hours. Previous research had suggested that an annual income of more than $75,000 might not improve people’s day-to-day lives, and that notion has been widely circulated. But this study appears to disagree. Seen from a moment-by-moment angle, Killingsworth said, the data show “evidence that happiness rises continuously, far above $75,000,” which means there’s reason to believe that more money really does improve people’s lives. “If you have more money, you can choose how to spend your time and how to direct your life,” said Killingsworth, a senior fellow at the University of Pennsylvania’s Wharton School of Business, in Philadelphia. Stress reduction This study found that a sense of control accounted for as much as 74% of the apparent link between greater income and greater well-being. People who earn more spend less time stressing out about bills, Killingsworth noted. The study found that…  read on >  read on >

Millionaires, rejoice! It turns out that money can, in fact, buy happiness. And a new study suggests more is better, with well-being rising as earnings grow. “Having more money gives people a greater sense of control over life,” said study author Matthew Killingsworth. The finding stems from more than 1.7 million real-time reports of well-being from more than 33,000 U.S. adults. They were prompted by their cellphones to answer the question “How do you feel right now?” at random times during their waking hours. Previous research had suggested that an annual income of more than $75,000 might not improve people’s day-to-day lives, and that notion has been widely circulated. But this study appears to disagree. Seen from a moment-by-moment angle, Killingsworth said, the data show “evidence that happiness rises continuously, far above $75,000,” which means there’s reason to believe that more money really does improve people’s lives. “If you have more money, you can choose how to spend your time and how to direct your life,” said Killingsworth, a senior fellow at the University of Pennsylvania’s Wharton School of Business, in Philadelphia. Stress reduction This study found that a sense of control accounted for as much as 74% of the apparent link between greater income and greater well-being. People who earn more spend less time stressing out about bills, Killingsworth noted. The study found that…  read on >  read on >

Previous coronavirus infections might prime the immune system to fight the new coronavirus that causes COVID-19, a new study suggests. There are numerous types of coronaviruses, including many harmless ones that cause mild upper respiratory infections similar to the common cold. Besides SARS-CoV-2 — the virus that causes COVID-19 — other deadly coronaviruses include MERS-CoV, which caused a 2012 outbreak in Saudi Arabia of Middle East respiratory syndrome, and SARS-CoV-1, the first pandemic coronavirus that caused the 2003 severe acute respiratory syndrome (SARS) outbreak. The authors of the new study investigated how coronaviruses affect the human immune system and also took a closer look at the workings of the antibody response. “Our results suggest that the COVID-19 virus may awaken an antibody response that existed in humans prior to our current pandemic, meaning that we might already have some degree of pre-existing immunity to this virus,” said study senior author John Altin. He’s an assistant professor in the infectious disease branch at the Translational Genomics Research Institute, in Flagstaff, Ariz. The findings could help scientists develop new diagnostic techniques and treatments, assess the effectiveness of convalescent plasma, and design new vaccines or monoclonal antibody therapies that can protect against mutations that may occur in the COVID-19 virus, according to the researchers. The study was published Jan. 19 in the journal Cell Reports Medicine. “Our findings…  read on >  read on >

Millionaires, rejoice! It turns out that money can, in fact, buy happiness. And a new study suggests more is better, with well-being rising as earnings grow. “Having more money gives people a greater sense of control over life,” said study author Matthew Killingsworth. The finding stems from more than 1.7 million real-time reports of well-being from more than 33,000 U.S. adults. They were prompted by their cellphones to answer the question “How do you feel right now?” at random times during their waking hours. Previous research had suggested that an annual income of more than $75,000 might not improve people’s day-to-day lives, and that notion has been widely circulated. But this study appears to disagree. Seen from a moment-by-moment angle, Killingsworth said, the data show “evidence that happiness rises continuously, far above $75,000,” which means there’s reason to believe that more money really does improve people’s lives. “If you have more money, you can choose how to spend your time and how to direct your life,” said Killingsworth, a senior fellow at the University of Pennsylvania’s Wharton School of Business, in Philadelphia. Stress reduction This study found that a sense of control accounted for as much as 74% of the apparent link between greater income and greater well-being. People who earn more spend less time stressing out about bills, Killingsworth noted. The study found that…  read on >  read on >

Previous coronavirus infections might prime the immune system to fight the new coronavirus that causes COVID-19, a new study suggests. There are numerous types of coronaviruses, including many harmless ones that cause mild upper respiratory infections similar to the common cold. Besides SARS-CoV-2 — the virus that causes COVID-19 — other deadly coronaviruses include MERS-CoV, which caused a 2012 outbreak in Saudi Arabia of Middle East respiratory syndrome, and SARS-CoV-1, the first pandemic coronavirus that caused the 2003 severe acute respiratory syndrome (SARS) outbreak. The authors of the new study investigated how coronaviruses affect the human immune system and also took a closer look at the workings of the antibody response. “Our results suggest that the COVID-19 virus may awaken an antibody response that existed in humans prior to our current pandemic, meaning that we might already have some degree of pre-existing immunity to this virus,” said study senior author John Altin. He’s an assistant professor in the infectious disease branch at the Translational Genomics Research Institute, in Flagstaff, Ariz. The findings could help scientists develop new diagnostic techniques and treatments, assess the effectiveness of convalescent plasma, and design new vaccines or monoclonal antibody therapies that can protect against mutations that may occur in the COVID-19 virus, according to the researchers. The study was published Jan. 19 in the journal Cell Reports Medicine. “Our findings…  read on >  read on >

Millionaires, rejoice! It turns out that money can, in fact, buy happiness. And a new study suggests more is better, with well-being rising as earnings grow. “Having more money gives people a greater sense of control over life,” said study author Matthew Killingsworth. The finding stems from more than 1.7 million real-time reports of well-being from more than 33,000 U.S. adults. They were prompted by their cellphones to answer the question “How do you feel right now?” at random times during their waking hours. Previous research had suggested that an annual income of more than $75,000 might not improve people’s day-to-day lives, and that notion has been widely circulated. But this study appears to disagree. Seen from a moment-by-moment angle, Killingsworth said, the data show “evidence that happiness rises continuously, far above $75,000,” which means there’s reason to believe that more money really does improve people’s lives. “If you have more money, you can choose how to spend your time and how to direct your life,” said Killingsworth, a senior fellow at the University of Pennsylvania’s Wharton School of Business, in Philadelphia. Stress reduction This study found that a sense of control accounted for as much as 74% of the apparent link between greater income and greater well-being. People who earn more spend less time stressing out about bills, Killingsworth noted. The study found that…  read on >  read on >

Previous coronavirus infections might prime the immune system to fight the new coronavirus that causes COVID-19, a new study suggests. There are numerous types of coronaviruses, including many harmless ones that cause mild upper respiratory infections similar to the common cold. Besides SARS-CoV-2 — the virus that causes COVID-19 — other deadly coronaviruses include MERS-CoV, which caused a 2012 outbreak in Saudi Arabia of Middle East respiratory syndrome, and SARS-CoV-1, the first pandemic coronavirus that caused the 2003 severe acute respiratory syndrome (SARS) outbreak. The authors of the new study investigated how coronaviruses affect the human immune system and also took a closer look at the workings of the antibody response. “Our results suggest that the COVID-19 virus may awaken an antibody response that existed in humans prior to our current pandemic, meaning that we might already have some degree of pre-existing immunity to this virus,” said study senior author John Altin. He’s an assistant professor in the infectious disease branch at the Translational Genomics Research Institute, in Flagstaff, Ariz. The findings could help scientists develop new diagnostic techniques and treatments, assess the effectiveness of convalescent plasma, and design new vaccines or monoclonal antibody therapies that can protect against mutations that may occur in the COVID-19 virus, according to the researchers. The study was published Jan. 19 in the journal Cell Reports Medicine. “Our findings…  read on >  read on >