All Sauce from Weekly Gravy:

Enjoy a pint of beer, a glass of wine or a dram of whiskey? Then make sure you have some healthy eats and a good dose of exercise on the side, a new study says. A healthy diet and regular physical activity can protect your liver at least partially from the harmful effects of alcohol, researchers reported Aug. 27 in the Journal of Hepatology. Any amount of daily alcohol intake or binge drinking increases a person’s risk of death from liver damage, researchers found. But a good diet and more exercise significantly blunt that risk, even if you’re a heavy drinker or binge drinker, results revealed. “We found that adherence to high levels of physical activity and/or diet quality was associated with a lower risk of liver-related death across all drinking patterns,” said senior researcher Dr. Naga Chalasani, a professor of gastroenterology and hepatology at Indiana University School of Medicine in Indianapolis. In the U.S., more than half (53%) of adults regularly imbibe, and about 178,000 people die from excess alcohol use each year, researchers said in background notes. For the study, researchers analyzed data from more than 60,000 participants in the U.S. National Health and Nutrition Examination Survey between 1984 and 2018. The survey asked people about their alcohol use, diet and exercise. Researchers defined heavy drinking as more than three drinks per day…  read on >  read on >

Eli Lilly says its new once-daily pill, orforglipron, helped people lose significant weight and lower blood sugar in a late-stage clinical trial.  The company plans to seek global regulatory approval later this year. The study included people with overweight, obesity and type 2 diabetes. Participants who took the highest dose of the drug (36 milligrams) lost an average of 22.9 pounds — about 10.5% of their body weight — after 72 weeks. The pill also lowered A1C levels — a measure of blood sugar control — by 1.8% on average, CNN reported. Those results, which have not been peer-reviewed, were lower than weight loss figures announced earlier this month, when the company reported that the highest dose helped patients shed an average 27.3 pounds, or 12.4% of their body weight.  Unlike Rybelsus, the only semaglutide pill currently available, orforglipron doesn’t require strict fasting or limited water intake.  The pill offers an alternative to injections, which some people find difficult or unpleasant. Eli Lilly says side effects were mostly mild to moderate, with upset stomach being the most common. If approved, orforglipron could offer millions of people with obesity or type 2 diabetes another treatment option. The company is also testing whether the pill may help with other conditions, including high blood pressure and sleep apnea. With earlier promising trial results, the company has been mass-producing…  read on >  read on >

The U.S. Centers for Disease Control and Prevention (CDC) will stop airing its “Tips From Former Smokers” ads at the end of September, ending a 13-year campaign that helped millions of Americans quit smoking. Launched in 2012, the campaign featured real people sharing the devastating health effects of smoking — and pointed viewers to free resources like the 800-QUIT-NOW helpline.  Independent research from RTI International showed that calls to the quitline surged whenever the ads ran and dropped sharply when they paused, CBS News said. One success story is Leslie Allison-Seei, who quit smoking after more than 40 years. In 2014, she began coughing up blood and was rushed to the hospital, where her doctor urged her to stop immediately.  “You’re done smoking as of today,” she recalled him saying. With nicotine patches, quitline support and a coach named Lori, Leslie quit the next day — and hasn’t smoked in over 11 years, according to CBS News. Research shows the campaign led to millions of attempts to stop smoking and more than 1 million long-term quits between 2012 and 2023.  It also saved billions of dollars in health care costs by preventing smoking-related illnesses. But funding for the program has been cut as part of a broader restructuring of the CDC’s chronic disease programs. Without new support, the ads — widely considered one of the…  read on >  read on >

Struggling to cope with today’s catastrophe-filled world? Changing your mindset can help protect you from the stress caused by disease outbreaks, wildfires, earthquakes, political uproars and traumatic life events, researchers say. People given a one-hour class in shifting their mindset — to see growth opportunities amidst chaos — wound up with lower levels of depression and stress months later, researchers report in the October issue of the journal Brain, Behavior and Immunity. “We would have liked to avoid the COVID-19 pandemic, but it came regardless,” said senior researcher Alia Crum, an associate professor of psychology at Stanford University in California. “In the post-pandemic era, we face a choice: We can let it recede into memory, leaving us depleted and disillusioned, or we can choose to look back, learn from it, and grow – both personally and collectively,” Crum said in a news release. Mindsets are the core beliefs, attitudes and assumptions that serve as a foundation for how people see and engage with the world, researchers said in background notes. These mental “lenses” can dramatically change how events affect a person. For the study, the research team tested the potential of altering a person’s mindset by showing two groups different videos. In all, 226 people were shown videos explaining how mindsets can be powerful drivers of health and well-being, highlighting the ways that people can…  read on >  read on >

Struggling to cope with today’s catastrophe-filled world? Changing your mindset can help protect you from the stress caused by disease outbreaks, wildfires, earthquakes, political uproars and traumatic life events, researchers say. People given a one-hour class in shifting their mindset — to see growth opportunities amidst chaos — wound up with lower levels of depression and stress months later, researchers report in the October issue of the journal Brain, Behavior and Immunity. “We would have liked to avoid the COVID-19 pandemic, but it came regardless,” said senior researcher Alia Crum, an associate professor of psychology at Stanford University in California. “In the post-pandemic era, we face a choice: We can let it recede into memory, leaving us depleted and disillusioned, or we can choose to look back, learn from it, and grow – both personally and collectively,” Crum said in a news release. Mindsets are the core beliefs, attitudes and assumptions that serve as a foundation for how people see and engage with the world, researchers said in background notes. These mental “lenses” can dramatically change how events affect a person. For the study, the research team tested the potential of altering a person’s mindset by showing two groups different videos. In all, 226 people were shown videos explaining how mindsets can be powerful drivers of health and well-being, highlighting the ways that people can…  read on >  read on >

Talk therapy has the power to alter a person’s physical brain structure, a new study shows. Psychotherapy caused measurable changes in the brains of people with severe depression, MRI scans revealed. Specifically, most patients experienced growth in brain regions responsible for processing emotions, researchers reported Aug. 26 in the journal Translational Psychology. The brain changes were similar to those produced by psychiatric medication, researchers said. “For the first time, we have a reliable biomarker for the effect of psychotherapy on brain structure,” said senior researcher Ronny Redlich, head of biological and clinical psychology at Martin Luther University Halle-Wittenberg in Germany. “Put simply, psychotherapy changes the brain,” he said in a news release. About 280 million people suffer from severe depression worldwide, researchers said in background notes. Depression has been linked to changes in the size of the hippocampus and amygdala, brain regions that help regulate emotions. For the new study, researchers provided a series of 20 cognitive-behavioral therapy sessions for 30 people diagnosed with depression. Cognitive-behavioral therapy (CBT) is an established method for treating depression, researchers noted. This form of therapy teaches people how to recognize and respond to thoughts and behaviors that contribute to their depression. “CBT leads to positive changes in thought patterns, emotions and behavior,” Redlich said. “We assume that this process is also linked to functional and structural changes in the…  read on >  read on >

Talk therapy has the power to alter a person’s physical brain structure, a new study shows. Psychotherapy caused measurable changes in the brains of people with severe depression, MRI scans revealed. Specifically, most patients experienced growth in brain regions responsible for processing emotions, researchers reported Aug. 26 in the journal Translational Psychology. The brain changes were similar to those produced by psychiatric medication, researchers said. “For the first time, we have a reliable biomarker for the effect of psychotherapy on brain structure,” said senior researcher Ronny Redlich, head of biological and clinical psychology at Martin Luther University Halle-Wittenberg in Germany. “Put simply, psychotherapy changes the brain,” he said in a news release. About 280 million people suffer from severe depression worldwide, researchers said in background notes. Depression has been linked to changes in the size of the hippocampus and amygdala, brain regions that help regulate emotions. For the new study, researchers provided a series of 20 cognitive-behavioral therapy sessions for 30 people diagnosed with depression. Cognitive-behavioral therapy (CBT) is an established method for treating depression, researchers noted. This form of therapy teaches people how to recognize and respond to thoughts and behaviors that contribute to their depression. “CBT leads to positive changes in thought patterns, emotions and behavior,” Redlich said. “We assume that this process is also linked to functional and structural changes in the…  read on >  read on >

Two-thirds of women in their child-bearing years have an increased risk for birth defects due to a lifestyle factor they can change, a new study says. These risk factors — low levels of vitamin B9 (folate), unmanaged diabetes or exposure to tobacco smoke — increase the odds of a serious birth defect in any child they might have, researchers said. Heart defects, cleft palates and defects of the brain and spinal cord are among the problems that could be headed off if women took steps to improve their health prior to pregnancy, researchers reported today in the American Journal of Preventive Medicine. “Every growing family hopes for a healthy pregnancy and healthy baby,” said lead researcher Arick Wang, a senior health scientist at the National Center on Birth Defects and Developmental Disabilities. “Understanding modifiable risk factors for birth defects helps families, health care providers, and public health professionals make data-informed decisions that can lead to healthier pregnancies and babies,” Wang added in a news release. For the new study, researchers analyzed data for nearly 5,400 women of reproductive age, gathered between 2007 and 2020 as part of the National Health and Nutrition Examination Survey. About 66% had at least one known risk factor for birth defects that could be addressed, results show. These include:  Low folate status: Roughly 4 out of 5 women got less…  read on >  read on >