Artificial intelligence (AI) can help improve how premature babies are fed, giving them a better chance at normal growth and development, a new study says. Currently, preemies in a neonatal intensive care unit are fed by IV, receiving a drip-drop handmade blend of nutrients that doctors call total parenteral nutrition, or TPN. This is the only way to feed newborns whose digestive systems haven’t matured enough to properly absorb nutrients, researchers said. “Right now, we come up with a TPN prescription for each baby, individually, every day,” senior researcher Nima Aghaeepour, an associate professor of pediatrics at Stanford University, said in a news release. “We make it from scratch and provide it to them.” Unfortunately, the process is error-prone, and it’s tough for docs to know if they’ve gotten the formula right, researchers said. There’s no blood test to measure whether a preemie has received enough daily calories, and preemies don’t necessarily cry when they’re hungry or become calm and content when they’re full. “Total parenteral nutrition is the single largest source of medical error in neonatal intensive care units, both in the United States and globally,” Aghaeepour said. To try to solve this problem, researchers trained an AI program on nearly 80,000 past prescriptions for preemie IV nutrition, linked to data on how the tiny patients fared. The AI uses information in a preemie’s…  read on >  read on >

Statins are very cheap and highly effective cholesterol-lowering drugs — but high-risk heart patients may have an even better option, a new evidence review says. Combining statins with another drug, ezetimibe, significantly reduces the risk of death in patients with clogged arteries, according to findings published March 23 in Mayo Clinic Proceedings. Using a high-dose statin with ezetimibe significantly reduces levels of “bad” LDL cholesterol, increasing a person’s chances of reaching healthy levels by 85%, researchers found. The combo also brought about a 19% reduction in risk of death from any cause; a 16% reduction in heart-related deaths; an 18% decrease in the risk of a major cardiovascular health problem; and a 17% decline in stroke risk. This combination therapy would prevent more than 330,000 deaths a year worldwide among patients who have already suffered a heart attack, including almost 50,000 deaths in the U.S. alone, researchers said. “This study confirms that combined cholesterol lowering therapy should be considered immediately and should be the gold standard for treatment of very high-risk patients after an acute cardiovascular event,” senior researcher Dr. Peter Toth, a professor of clinical family and community medicine at the University of Illinois, said in a news release. Up to now, studies have been inconsistent regarding whether to provide combo cholesterol-lowering therapy immediately for high-risk patients, even before they suffer a heart attack…  read on >  read on >

Lifestyle factors like diet, exercise, smoking and blood pressure have a greater impact on the heart health of women than men, a new study says. Women with poor health have nearly five times the risk of heart disease compared to women with ideal health, according to findings scheduled for presentation Saturday at a meeting of the American College of Cardiology in Chicago. By comparison, men in poor health only have 2.5 times the risk of heart disease compared to men in ideal health. “For the same level of health, our study shows that the increase in risk [related to each factor] is higher in women than in men — it’s not one-size-fits-all,” lead researcher Dr. Maneesh Sud, an interventional cardiologist at Sunnybrook Health Sciences Center in Toronto, said in a news release. The new study is the first to show that such lifestyle risks are more strongly linked to women’s heart health, researchers said. “This is novel and something that hasn’t been seen in other studies,” Sud said. The study focused on eight factors associated with heart disease: diet, sleep, exercise, smoking, body mass index, blood sugar, cholesterol and blood pressure. (Body mass index is a estimate of body fat based on height and weight.) Researchers looked at these factors in more than 175,000 Canadian adults who enrolled in the Ontario Health Study between 2009…  read on >  read on >

How should a person eat in middle age to protect their health as they grow older? One diet came out a clear winner in a 30-year study involving more than 105,000 men and women and eight diets, researchers reported in the journal Nature Medicine. People whose dietary pattern more closely stuck to the Alternative Healthy Eating Index (AHEI) in middle-age had the greatest likelihood of good health in their 70s, researchers say. Those with the highest AHEI score had 86% better odds of healthy aging at 70, and were 2.2 times more likely to be healthy at 75, results show. The AHEI centers on a diet rich in fruits, vegetables, whole grains, nuts, legumes and healthy fats, and low in red and processed meats, sugary drinks, sodium and refined grains, researchers said. “Our findings suggest that dietary patterns rich in plant-based foods, with moderate inclusion of healthy animal-based foods, may promote overall healthy aging and help shape future dietary guidelines,” co-senior researcher Marta Guasch-Ferré, an associate professor of public health at the University of Copenhagen and adjunct associate professor of nutrition at the Harvard T.H. Chan School of Public Health, said in a news release. Harvard researchers created the AHEI in 2002 as an alternative to the U.S. Department of Agriculture’s Healthy Eating Index, which measures how well people’s diets stick to the federal Dietary…  read on >  read on >

A rare red meat allergy, usually linked to a bite from the lone star tick, may also be caused by other tick species found in different parts of the U.S., a new report shows. “Alpha-gal syndrome is relatively rare, but those who have it can have a full-on anaphylactic shock,” Douglas Norris, a professor of molecular microbiology and immunology at the Johns Hopkins Bloomberg School of Public Health, said in a report from NBC News. The U.S. Centers for Disease Control and Prevention (CDC) estimates nearly 450,000 people in the U.S. have this condition. Most cases are linked to the lone star tick, which is common in the Southeast and lower Midwest.  But new case reports from Maine and Washington state found two women who developed alpha-gal syndrome after being bitten by ticks in places where lone star ticks aren’t common. This suggests that other types of ticks, like the black-legged tick (also called deer tick) that transmits the bacteria that causes Lyme disease, and the western black-legged tick, may also cause the condition. “We do believe the lone star tick is still responsible for most of the cases of alpha-gal syndrome in the U.S.,” Dr. Johanna Salzer, a veterinary medical officer and epidemiologist with the CDC’s Division of Vector-Borne Diseases, told NBC News. In the Washington case, a 61-year-old woman went into anaphylactic shock…  read on >  read on >