Full doses of blood thinners can benefit patients hospitalized with COVID-19, but the severity of their illness matters, researchers say. The new global analysis found that hospitalized patients with moderate COVID-19 may benefit from the drugs’ clot-preventing powers, but patients with illness so severe it requires admission to an intensive care unit may not. “SARS-CoV-2 infection can increase the risk for developing blood clots by causing a significant inflammatory response in the body,” explained Dr. Aeshita Dwivedi, a cardiologist at Lenox Hill Hospital in New York City. “These blood clots can further lead to debilitating and life-threatening conditions like heart attacks, strokes or pulmonary embolisms,” said Dwivedi, who wasn’t involved in the new study. She said the new data “has demonstrated that a higher dose of blood thinners, in addition to being safe, reduced the need for life support and possibly even death” in moderately ill patients in the hospital. Early in the COVID-19 pandemic, doctors worldwide noted that COVID-19 patients had high rates of blood clots and inflammation that led to complications, such as lung failure, heart attack and stroke. At the time, it wasn’t known whether providing COVID-19 patients with high doses of blood thinners would be safe and effective. Last December, the same group of researchers released findings showing that routine use of full-dose blood thinners in more critically ill COVID-19 patients…  read on >  read on >

Researchers have found a way to track what your mind is doing when thoughts begin to wander. Using electroencephalograms (EEG) to measure brain activity while more than two dozen study participants did mundane attention tasks, the researchers identified brain signals associated with a daydreaming mind. They found that the participants had increased alpha brain waves in the prefrontal cortex when their thoughts skipped from one topic to another. Alpha waves are slow brain rhythms with frequency ranging from 9 to 14 cycles per second. The findings provide an electrophysiological signature for free, spontaneous thought, according to the researchers. They also found that the participants had weaker brain signals known as P3 in the parietal cortex when they weren’t paying attention to the task at hand. The study was published this week in the Proceedings of the National Academy of Sciences. “For the first time, we have neurophysiological evidence that distinguishes different patterns of internal thought, allowing us to understand the varieties of thought central to human cognition and to compare between healthy and disordered thinking,” study senior author Robert Knight, professor of psychology and neuroscience at the University of California, Berkeley, said in a university news release. The findings suggest that tuning out the outside world and letting your thoughts flow freely and creatively are necessary to promote mind relaxation and exploration, according to the…  read on >  read on >

Here’s one reason why past or current smoking may handicap you if you are battling breast cancer: New research suggests that nicotine promotes the spread of the disease to your lungs. Smoking is known to increase the risk that breast cancer will spread, which lowers the survival rate by one-third at diagnosis. But the role of nicotine in the spread of breast cancer to the lungs has been less clear. To learn more, researchers studied almost 1,100 breast cancer patients. They found that current smokers and former smokers had higher rates of breast cancer spread to the lungs than those who never smoked. In studies of mice, researchers found that nicotine fosters that spread. And this was true even after no exposure to nicotine for 30 days. That suggests there’s an ongoing risk for breast cancer patients who are former smokers, according to the team from Wake Forest School of Medicine in Winston-Salem, N.C. Their findings were published online Jan. 20 in the journal Nature Communications. “Our data shows that nicotine exposure creates an environment in the lungs that is ripe for metastatic growth,” said lead study author Kounosuke Watabe, a professor of cancer biology at Wake Forest. Long-term exposure to nicotine creates an “inflammatory microenvironment” in the lungs. That attracts immune cells called neutrophils, which release a protein that encourages the spread of cancer,…  read on >  read on >

Puffy coats have their place, but it’s not inside a car seat. The American Academy of Pediatrics (AAP) offers a variety of tips for keeping your little ones safe and warm while traveling by car. The first is to avoid dressing children in puffy coats or snowsuits before buckling them in, because car seat straps won’t tighten enough. That creates a danger that the fluffy padding will flatten in the force of a crash and the youngster will slip from the seat and be thrown from the car. Puffy coats are not safe in a car seat or under a seat belt for someone of any age, the AAP said. “Parents may not recognize the potential danger of buckling up a child who is wearing a puffy coat,” said Dr. Sarah Denny, a pediatrician with expertise in injury prevention. “A car seat harness or belt needs to fit snugly enough so that you cannot pinch the straps of the car seat harness. A safer alternative is to drape a blanket or coat over the car straps.” The AAP offers additional tips, including staying warmer by storing the carrier portion of an infant seat indoors and packing extra socks, mittens and hats. If your child likes to suck his or her thumb, choose half-gloves with open fingers. Dress your child in thin layers. This would include…  read on >  read on >

Puffy coats have their place, but it’s not inside a car seat. The American Academy of Pediatrics (AAP) offers a variety of tips for keeping your little ones safe and warm while traveling by car. The first is to avoid dressing children in puffy coats or snowsuits before buckling them in, because car seat straps won’t tighten enough. That creates a danger that the fluffy padding will flatten in the force of a crash and the youngster will slip from the seat and be thrown from the car. Puffy coats are not safe in a car seat or under a seat belt for someone of any age, the AAP said. “Parents may not recognize the potential danger of buckling up a child who is wearing a puffy coat,” said Dr. Sarah Denny, a pediatrician with expertise in injury prevention. “A car seat harness or belt needs to fit snugly enough so that you cannot pinch the straps of the car seat harness. A safer alternative is to drape a blanket or coat over the car straps.” The AAP offers additional tips, including staying warmer by storing the carrier portion of an infant seat indoors and packing extra socks, mittens and hats. If your child likes to suck his or her thumb, choose half-gloves with open fingers. Dress your child in thin layers. This would include…  read on >  read on >

Researchers have found a way to track what your mind is doing when thoughts begin to wander. Using electroencephalograms (EEG) to measure brain activity while more than two dozen study participants did mundane attention tasks, the researchers identified brain signals associated with a daydreaming mind. They found that the participants had increased alpha brain waves in the prefrontal cortex when their thoughts skipped from one topic to another. Alpha waves are slow brain rhythms with frequency ranging from 9 to 14 cycles per second. The findings provide an electrophysiological signature for free, spontaneous thought, according to the researchers. They also found that the participants had weaker brain signals known as P3 in the parietal cortex when they weren’t paying attention to the task at hand. The study was published this week in the Proceedings of the National Academy of Sciences. “For the first time, we have neurophysiological evidence that distinguishes different patterns of internal thought, allowing us to understand the varieties of thought central to human cognition and to compare between healthy and disordered thinking,” study senior author Robert Knight, professor of psychology and neuroscience at the University of California, Berkeley, said in a university news release. The findings suggest that tuning out the outside world and letting your thoughts flow freely and creatively are necessary to promote mind relaxation and exploration, according to the…  read on >  read on >

Here’s one reason why past or current smoking may handicap you if you are battling breast cancer: New research suggests that nicotine promotes the spread of the disease to your lungs. Smoking is known to increase the risk that breast cancer will spread, which lowers the survival rate by one-third at diagnosis. But the role of nicotine in the spread of breast cancer to the lungs has been less clear. To learn more, researchers studied almost 1,100 breast cancer patients. They found that current smokers and former smokers had higher rates of breast cancer spread to the lungs than those who never smoked. In studies of mice, researchers found that nicotine fosters that spread. And this was true even after no exposure to nicotine for 30 days. That suggests there’s an ongoing risk for breast cancer patients who are former smokers, according to the team from Wake Forest School of Medicine in Winston-Salem, N.C. Their findings were published online Jan. 20 in the journal Nature Communications. “Our data shows that nicotine exposure creates an environment in the lungs that is ripe for metastatic growth,” said lead study author Kounosuke Watabe, a professor of cancer biology at Wake Forest. Long-term exposure to nicotine creates an “inflammatory microenvironment” in the lungs. That attracts immune cells called neutrophils, which release a protein that encourages the spread of cancer,…  read on >  read on >

Puffy coats have their place, but it’s not inside a car seat. The American Academy of Pediatrics (AAP) offers a variety of tips for keeping your little ones safe and warm while traveling by car. The first is to avoid dressing children in puffy coats or snowsuits before buckling them in, because car seat straps won’t tighten enough. That creates a danger that the fluffy padding will flatten in the force of a crash and the youngster will slip from the seat and be thrown from the car. Puffy coats are not safe in a car seat or under a seat belt for someone of any age, the AAP said. “Parents may not recognize the potential danger of buckling up a child who is wearing a puffy coat,” said Dr. Sarah Denny, a pediatrician with expertise in injury prevention. “A car seat harness or belt needs to fit snugly enough so that you cannot pinch the straps of the car seat harness. A safer alternative is to drape a blanket or coat over the car straps.” The AAP offers additional tips, including staying warmer by storing the carrier portion of an infant seat indoors and packing extra socks, mittens and hats. If your child likes to suck his or her thumb, choose half-gloves with open fingers. Dress your child in thin layers. This would include…  read on >  read on >

Puffy coats have their place, but it’s not inside a car seat. The American Academy of Pediatrics (AAP) offers a variety of tips for keeping your little ones safe and warm while traveling by car. The first is to avoid dressing children in puffy coats or snowsuits before buckling them in, because car seat straps won’t tighten enough. That creates a danger that the fluffy padding will flatten in the force of a crash and the youngster will slip from the seat and be thrown from the car. Puffy coats are not safe in a car seat or under a seat belt for someone of any age, the AAP said. “Parents may not recognize the potential danger of buckling up a child who is wearing a puffy coat,” said Dr. Sarah Denny, a pediatrician with expertise in injury prevention. “A car seat harness or belt needs to fit snugly enough so that you cannot pinch the straps of the car seat harness. A safer alternative is to drape a blanket or coat over the car straps.” The AAP offers additional tips, including staying warmer by storing the carrier portion of an infant seat indoors and packing extra socks, mittens and hats. If your child likes to suck his or her thumb, choose half-gloves with open fingers. Dress your child in thin layers. This would include…  read on >  read on >

Not many people have had the opportunity to get the COVID-19 vaccine yet. But while you wait your turn, there are some steps you can take to give the vaccine — whichever brand you get — a boost when it’s available to you. An Ohio State University review of 49 vaccine studies dating back 30 years examined how stress, depression and healthy behaviors, such as exercise, can affect immune response to a vaccine. Although it’s not realistic to entirely transform your health and habits in a few weeks or months, there are some steps everyone can take — even last-minute ones — to make a difference. Those include getting good sleep as well as exercise in the days before and after you get your shot, said the review’s senior author, Janice Kiecolt-Glaser. She is director of Ohio State’s Institute for Behavioral Medicine Research, in Columbus. “There are several things that are really reasonable and relatively easy,” she said. Pandemic-related stress may have set people back when it comes to maintaining the behaviors that keep them healthier, the study authors noted. Recent data from around the world have revealed higher rates of depression and anxiety, more insomnia, increased alcohol sales and more overeating, according to the review. The studies in this review looked at the effects of psychological factors and behaviors on immune response to a…  read on >  read on >