The Federal Assault Weapons Ban (FAWB) would have prevented as many as 38 mass shootings that have taken place since the law lapsed in 2005, a new study estimates. Enacted by Congress in 1994, the ban prohibited the sale and manufacture of certain military-style semiautomatic weapons in the United States – including notoriously deadly weapons like AK-47s, AR-15s, TEC-9s and “Street Sweeper” shotguns with high-capacity revolving cylinders. There have been multiple attempts to renew the ban, but none have succeeded. While the ban was in place, would-be mass shooters denied access to an assault weapon did not turn to other types of firearms to carry out a massacre, researchers found. “These results suggest that the FAWB discouraged potential perpetrators from committing a mass shooting with an assault weapon, and, furthermore, that these potential perpetrators did not simply carry out attacks with other types of weapons,” said lead researcher Alexander Lundberg, an assistant professor of emergency medicine at Northwestern University School of Medicine, in Chicago. For the study, researchers looked for events in which at least four people were killed by a firearm. A total of 184 such mass shootings have occurred between 1966 and 2022. The researchers then looked at trends before, during and after the assault weapon ban, to estimate the number of mass shootings that relied on such firearms. While it was active,…  read on >  read on >

One in three former NFL players believe they have football-related brain damage that’s doing untold harm to their lives, a new study finds. Unfortunately, their fears might be harming their mental health on top of whatever risks they face from head injuries sustained during their careers, researchers report. About one-third of nearly 2,000 retired NFL players believe they have chronic traumatic encephalopathy (CTE), a degenerative brain condition linked to repeated head trauma, researchers reported Sept. 23 in the journal JAMA Neurology. Players who suspect they have CTE reported significantly more problems with brain function, low testosterone, depression and chronic pain than those who don’t think they have the condition, researchers found. In addition, about 25% of players who believe they have CTE also reported suicidal thoughts or behaviors, compared with about 5% of those who don’t think they have CTE, results showed. NFL retirees who believe they have CTE are twice as likely to report frequent thoughts of suicide, even after accounting for symptoms of depression, researchers said. These symptoms are potentially related to the dread faced by NFL retirees who are certain they have CTE and expect a long and excruciating decline in their mental function, researchers said. Incurable brain diseases like Alzheimer’s, Parkinson’s and Huntington’s disease also have been associated with elevated suicide rates. “As complex human beings, our beliefs can exert a…  read on >  read on >

Research in rats and hibernating squirrels has pinpointed a naturally occurring protein that appears to reverse cataracts, scientists report. Animal studies don’t always pan out in people, of course. But the discovery of the RNF114 protein raises the possibility of surgery-free cataract removal, according to a team from the U.S. National Eye Institute (NEI). “Understanding the molecular drivers of this reversible cataract phenomenon might point us in a direction toward a potential treatment strategy,” said the study’s co-lead investigator, Wei Li. He’s a senior investigator in the NEI’s Retinal Neurophysiology Section. His team published its findings Sept. 17 in the Journal of Clinical Investigation. As the NEI explained, “a cataract is a cloudy area in the lens of your eye [the clear part of the eye that helps to focus light]. This can make your vision cloudy.” Right now, surgery is a patient’s only treatment option, and almost 4 million such procedures are conducted in the United States each year. A non-surgical approach has long been a holy grail of ophthalmological research. Meanwhile, anyone living in the American heartland has probably seen a 13-lined ground squirrel. These hardy creatures are perfect for cataract research, Li’s team explained, because their retinas contain light-sensitive photoreceptor cells that are mostly cones, not the “rods and cones” found in the human eye. Cones are especially tied to color vision. These prairie squirrels can also withstand…  read on >  read on >

Antidepressants have the potential to improve memory and thinking skills, a new study suggests. Some patients experienced a boost on brain tests after taking the SSRI antidepressant escitalopram (Lexapro), researchers report. The drug appeared to affect a serotonin receptor in the brain called the 5HT4 receptor, according to results published recently in the journal Biological Psychiatry. Serotonin is described as a “feel good” hormone, researchers said in background notes. Higher levels of serotonin in the brain contribute to a sense of well-being and have been shown to ease clinical depression. “It seems that the SSRI medication contributes to an improvement on cognitive function, at the same time as helping improve mood,” said lead investigator Vibeke Dam, a senior researcher in neurology and neurobiology with Copenhagen University Hospital in Denmark. “Our work ties the improvement in cognitive function to the specific 5HT4 receptor and suggest that direct serotonin 4 receptor stimulation may be an important pro-cognitive target to consider in optimizing outcomes of antidepressant treatment,” Dam added in a journal news release. “It also reinforces the idea that serotonin is crucial to mood improvement.” For the study, researchers scanned the brains of 90 depressed patients to measure 5HT4 receptor function in their brains. The patients also were tested for mood problems and cognitive abilities. Then the patients were given daily escitalopram (Lexapro) for eight weeks. At…  read on >  read on >

It’s that time of year when respiratory viruses start to circulate widely, but how can you tell the difference between the symptoms of a cold, the flu and COVID? Dr. William Brian Glenn, from Hackensack Meridian Medical Group in New Jersey, shares what you need to know to be ready for whatever virus comes your way this fall and winter. The challenge with cold, flu and COVID-19 is that the symptoms for each are similar, Glenn noted. A cold can show up as cough, sneezing, runny nose, sore throat and fatigue, while the flu can include all of those symptoms plus headache, fever, chills, body aches and fatigue. Meanwhile, COVID can present with cold and flu symptoms, along with a loss of taste or smell, diarrhea, nausea and vomiting, or shortness of breath, Glenn said. Cold symptoms tend to come on gradually, while flu symptoms come on suddenly. COVID symptoms take between two and 14 days after exposure to surface — and can progress to more severe symptoms in some people. Are some people more at risk of developing colds, flu and COVID-19 than others? The elderly, as well as children and adults with chronic conditions including diabetes, lung or kidney disease, metabolic disorders, heart disease and cancer are more susceptible to respiratory infections. Taking certain medicines that weaken the immune system can also put…  read on >  read on >

Heavy-duty endurance exercise can cause body fat levels to drop without any accompanying weight loss, a new small-scale study indicates. A group of eleven middle-aged men who cycled 710 miles in seven days lost only about 1% of their total weight, because they ate and drank enough to offset the calorie burn. But they lost over 9% of their overall body fat, including a nearly 15% reduction in levels of dangerous visceral fat crowding their vital organs. The cyclists also experienced a more than 20% reduction in total cholesterol and a nearly 40% reduction in triglyceride levels, as well as a substantial reductions in blood pressure. The results “support the importance of promoting a physically active lifestyle rather than caloric restriction in obesity prevention,” concluded the research team led by co-senior author Jean-Pierre Despres, a professor of kinesiology with University Laval in France. In other words, the study “provides evidence that humans were designed to be physically active rather than eat as little as possible,” researchers wrote. For the study, researchers recruited 11 recreational male cyclists ages 50 to 66 who could maintain an average pace of nearly 19 miles per hour over long distances. The men all hailed from the Quebec City metropolitan area in Canada. During seven consecutive days, the cyclists were sent once or twice on a 64-mile road loop on the…  read on >  read on >

Each year, an average of 174 U.S. kids under the age of 5 lose their lives over causes linked to nursery products. Many of these tragedies could be prevented, and the Consumer Product Safety Commission (CPSC) on Thursday issued a list of products deemed most hazardous. Leading the list by far: Any soft bedding added into cribs, bassinets and playpens. These products alone were part of the cause of 126 child deaths between 2019 and 2021, the CPSC said. Also implicated: Inclined infant “sleepers” and similar products, and infant carriers. Together, soft bedding, inclined sleepers and baby carriers were tied to three-quarters (76%) of deaths, the agency said. Many of these products are unnecessary as well as dangerous, said CPSC Chair Alex Hoehn-Saric. “Babies aren’t little adults. They don’t need pillows and blankets to feel comfortable and safe when they sleep,” Hoehn-Saric said in a CPSC news release. “The safest way for your baby to sleep is without blankets, pillows, or other items surrounding them. A firm flat surface in a crib, bassinet, play yard or bedside sleeper with just a fitted sheet is all they need.” Always put infants to bed on their backs, to cut the risk for sudden unexpected infant death syndrome (SIDS/SUID) and suffocation. If your baby falls asleep while in a swing, bouncer, lounger or similar product, transfer them to…  read on >  read on >

It’s called the MIND diet and its primary aim is to help guard against thinking and memory declines as you age. But does it work? Yes, claims new research that found following the MIND diet for 10 years produced a small but significant decrease in the risk of developing thinking, memory and concentration problems. “With the number of people with dementia increasing with the aging population, it’s critical to find changes that we can make to delay or slow down the development of cognitive problems,” lead study author Dr. Russell Sawyer, an assistant professor of clinical neurology and rehabilitation medicine at the University of Cincinnati’s Gardner Neuroscience Institute, said in a news release on the study. “We were especially interested to see whether diet affects the risk of cognitive impairment in both Black and white study participants.” How does the diet work its magic? The MIND (Mediterranean-DASH Intervention for Neurodegenerative Delay) diet joins elements of the Mediterranean diet and the DASH diet, which focuses on reducing blood pressure. “Among the MIND diet components are 10 brain-healthy food groups — green leafy vegetables, other vegetables, nuts, berries, beans, whole grains, seafood, poultry, olive oil and wine,” Sawyer told CNN. Meanwhile, five unhealthy food groups — red meats, butter and stick margarine, cheese, fried and fast foods, and pastries and sweets — are very limited in the MIND…  read on >  read on >

Exercise, whether moderate- or high-intensity, can help ease Parkinson’s symptoms, including fatigue, new research shows. As study lead author Dr. Philip Millar explained, Parkinson’s patients are too often overwhelmed by shame or depression, so they stop going to the gym or exercising. That’s too bad, Millar said, because “if you stop physical activity, your body adapts and you lose physical function.” Just how beneficial can exercise be for patients? To find out, Millar’s team at the University of Guelph, in Ontario, Canada, had three groups of 10 people in various stages of Parkinson’s disease. Each group exercised three times per week at the gym, for a period of 10 weeks. The male and female participants ranged in age from 45 to 79, and they engaged in one of two modes of exercise training, moderate intensity or high intensity. Millar’s team tracked various physiological metrics — the person’s “maximal oxygen consumption,” their level of fatigue or vulnerability to fatigue, gait, balance and motor symptoms. “Prior work found that high-intensity interval training may improve how far someone with Parkinson’s can walk, but this could be due to becoming more stable or confident in their gait,” said Millar, who is an associate professor of human health and nutritional science at Guelph. “It might have had nothing to do with cardiorespiratory fitness and the impact on motor symptoms was…  read on >  read on >

There have been 50 face transplants performed in 11 countries since the surgery was pioneered back in 2005, and long-term outcomes have been favorable, a new review finds. In total, 85% of people receiving these complex surgeries survived five years and 74% were still alive a decade after transplant completion, researchers report. When the numbers focused on deaths linked to the transplants per se, five- and ten-year survival rose to 96% and 83%, respectively. That’s significantly better than survival for other types of transplant, said the team of Finnish researchers. For example, at 10 years post-surgery, survival for liver transplants reaches 61% and for heart transplants the number is 65%, they noted. “The first 50 face transplants in the world during a period of 18 years demonstrate a promising survival rate of the grafts, exceeding several solid organ transplants,” concluded a team led by Dr. Pauliina Homsy, from the department of plastic surgery at the University of Helsinki. Her team published their report Sept. 18 in the journal JAMA Surgery. Homsy’s team collected data on all 50 face transplants conducted in 48 patients, carried out at 18 centers in 11 countries. Two of the patients required a second transplant, which in each case proved successful, the researchers noted. Nineteen patients were operated on in North America (18 in the United States), 29 in Europe, 1…  read on >  read on >