GLP-1 weight-loss drugs like Ozempic and Zepbound are so effective it might seem that a person can lose weight without doing anything at all. But that’s a false notion, experts say. Losing weight properly and keeping it off will require lifestyle changes that extend beyond a weekly GLP-1 injection. “Many patients lose muscle mass in addition to fat mass and have GI symptoms that lead to stopping medication,” senior researcher Dr. JoAnn Manson said in a news release. She’s chief of preventive medicine at Brigham and Women’s Hospital in Boston. These potential problems prompted experts to craft a set of diet and exercise tips specifically for people on GLP-1 meds. The suggestions were published July 14 in JAMA Internal Medicine. “We propose an approach to improving outcomes on GLP-1s by preserving lean body mass, ensuring good nutrition, and managing symptoms that can otherwise lead to stopping medications,” Manson said. For example, lean muscle mass accounts for 25% to 40% of the weight a person loses when using GLP-1 drugs, experts noted. “Begin each meal with 20 to 30 grams of protein from foods like fish, beans, chickpeas, or tofu,” the recommendations state. “Aim for 1.0 to 1.5 g of protein per kilogram of body weight daily, if moderately active. If your appetite is very low, use protein shakes with at least 20 g protein per… read on > read on >

















