All Sauce from Weekly Gravy:

About 93% of people worldwide who struggle with mental health or substance abuse issues aren’t getting adequate care, a new report finds. In many cases, people affected by mental illness do not recognize that they have a diagnosable condition, the Canadian research team found.  But even when diagnoses are made, treatment is often lacking.  Men seemed more likely to go untreated than women, the study found.  Globally, “women were 50% more likely to receive effective treatment despite men having more than twice the substance use disorders prevalence and suicide death rate than women,” wrote a team led by Dr. Daniel Vigo. He’s an associate professor of psychiatry and population and public health at the University of British Columbia in Vancouver. The new data came from World Health Organization surveys involving nearly 57,000 participants in 21 countries, conducted over a 19-year period.  Countries included the United States and Japan, as well as many nations in Western and Eastern Europe and South America. Participants all met standard criteria for having a mental illness, including substance abuse disorders. People were quizzed on whether they: Recognized their need for treatment Made contact with the healthcare system about it Received a minimum level of adequate treatment Received effective treatment Less than half (46.5%) recognized that they had a condition that merited treatment, the researchers reported.  In the group that did…  read on >  read on >

More than 800,000 U.S. children have what’s called “high threshold” peanut allergy, meaning they can tolerate about half a peanut daily before symptoms arise. New research suggests that exposing these kids to tiny but gradually increasing levels of store-bought peanut butter might help ease the allergy for good.  “Our study results suggest a safe, inexpensive and effective pathway for allergists to treat children with peanut allergy who can already tolerate the equivalent of at least half a peanut, considered a high-threshold peanut allergy,”  said study lead author Dr. Scott Sicherer, chief of allergy and immunology at Mount Sinai in New York City. He believes the findings could have implications for food allergies in general. “Our findings open the gateway to personalized threshold-based treatments of food allergy,” Sicherer said in a Mount Sinai news release, adding that the approach could “be a game-changer for the majority of people with food allergies.” The new trial was funded by the U.S. National Institute of Allergy and Infectious Diseases and published Feb. 10 in NEJM Evidence. For some children and adults, even minuscule amounts of peanut can trigger severe reactions, including life-threatening anaphylaxis. These cases — in which the amount of exposure needed is under half a peanut — are deemed to be “low-threshold” allergies.   The U.S. Food and Drug Administration (FDA) recently approved treatments, such as an injected…  read on >  read on >

When and what you eat might play a role in maintaining good mental health, a new study suggests. Researchers in China found that folks with heart disease were more likely to keep depression at bay if they ate a big, calorie-rich breakfast.  There’s evidence that heart disease patients “are more likely to develop depression when compared to the general population — and dietary factors have been shown to play an important role in depression occurrence and development,” noted a team led by Hongquan Xie of the Harbin Medical University. They published their findings recently in BMC Medicine. According to the researchers, the timing of calorie intake “can regulate circadian rhythms and metabolism,” and disruptions in circadian rhythms may be a contributor to depression. Heart disease patients are already at heightened risk for depression, so the new study looked at possible links between daily meals and a patient’s mental health. The team looked at 2003-2018 data from almost 32,000 Americans who enrolled in the U.S. National Health and Nutritional Examination Survey.  Almost 3,500 participants (averaging 66 years of age) had heart disease, and 554 of those people were also diagnosed with depression.  Survey participants also reported what and when they ate during a typical day. The data showed that people who took in the most calories at breakfast (791 calories on average) were 30% less prone to…  read on >  read on >

Yes, rare cases of vision issues have arisen in people taking popular GLP-1 weight loss drugs, but the jury’s out on whether the medications caused the eye trouble, according to a new small study. The study reviewed the cases of nine people who developed sight-robbing issues, such as dysfunction in blood vessels around the eye’s optic nerve, after taking a GLP-1.  “We’re trying to elucidate if being on these drugs can increase your risk,” said study co-author Dr. Norah Lincoff. She’s a neuro-ophthalmologist and professor of neurology at the University at Buffalo. The study, published recently in JAMA Opthalmology, focused on nine patients, all in their 50s or 60s, who were taking GLP-1s such as semaglutide (Wegovy/Ozempic) and tirzepatide (Mounjaro/Zepbound). Seven of the nine patients developed a condition known as nonarteritic anterior ischemic optic neuropathy (NAION). This occurs when blood vessels fail to supply enough blood to the optic nerve, which is crucial for sight. In NAION, damage to the nerve can lead to a sudden and permanent partial loss of vision. Lead study author Dr. Bradley Katz, of the John A. Moran Eye Center at University of Utah Health in Salt Lake City, first noted the issue in a patient who experienced a sudden and painless loss of vision in one eye after starting seamglutide. The patient briefly halted use of the drug, but when…  read on >  read on >

Appalachia has a rich history and gorgeous landscapes, but it has also experienced rates of cancer incidence and death that outstrip those of much of the rest of America. However, new data offer hope to the 26 million people living in the region: Cancer rates are falling, although not as steeply as elsewhere in America. Still, “there are reasons for hope and opportunities to increase access to preventive care in at-risk populations throughout Appalachia,” said study senior author Dr. B. Mark Evers, who directs the Markey Cancer Center at the University of Kentucky. He believes experts can “learn from this data where to focus on some of these problems that have been persistent for decades.” The new data were published Feb. 6 in the Journal of the American College of Surgeons. The research team defined Appalachia as 423 counties across 13 states near the eastern seaboard, from Mississippi to southern New York. Evers and colleagues looked at data on cancer incidence and death for the region from 2004 through 2021. The data came from sources such as the U.S. Census Bureau, the U.S. Cancer Statistics Incidence Analytics Database and the National Center for Health Statistics. Some of the findings were grim: For example, between 2017 and 2021, Americans living in Appalachia were 5.6% more likely to be diagnosed with cancer and 12.8% more likely to…  read on >  read on >

It’s long been known that certain complications of pregnancy can raise a woman’s risk for heart trouble years later. But new research shows that even the sisters of these women can be at higher heart risk — suggesting risks may be genetically shared within families. “It may be important to identify [all of] these women early to offer preventive treatment for pregnancy complications as well as lifestyle counseling and follow-up for cardiovascular disease risk,” study lead author Ängla Mantel said. She’s an associate professor in clinical epidemiology at the Karolinska Institute in Solna, Sweden. Conditions such as premature delivery and preeclampsia — spikes in blood pressure — are common but dangerous complications of pregnancy. And numerous studies have shown that experiencing these issues places a woman at higher risk of heart disease later in life. Mantel’s team wondered what the role of genetics might be in this predisposition. To find out, they looked at the medical records of more than 1.2 million Swedish women, all of who were free of heart disease when the study began.   Most had never had any complication of pregnancy, but the study also included nearly 166,000 women who did have a history of such issues, as well as about 61,000 of their sisters who had never had pregnancy complications. The team looked at medical records for a median 14…  read on >  read on >

Turns out, looking on the bright side may do more than lift your mood!  It could also help you save money, especially if you’re on a tight budget. A study published recently in the Journal of Personality and Social Psychology  found that people who are more optimistic about the future tend to save more money over time, even after accounting for income, personality traits and financial literacy. “We often think of optimism as rose-colored glasses that might lead people to save less for the future,” lead author Joe Gladstone of the University of Colorado Boulder, said in a news release. “But our research suggests optimism may actually be an important psychological resource that helps people save, especially when facing economic hardship.” The study analyzed data from more than 140,000 people across the U.S., the U.K. and 14 European countries. Researchers examined survey responses measuring “dispositional optimism” where participants rated statements like “Overall, I expect more good things to happen to me than bad,” or “In uncertain times, I usually expect the best.” What did they find?  Higher optimism was linked to greater savings, even among folks with lower incomes. And even a slight improvement in optimism scores was linked to $1,352 in savings. The link between optimism and savings remained even when researchers controlled for other factors like age, gender, relationship status, parental status, childhood…  read on >  read on >

Heavy weed use may be far more dangerous than people realize, according to a pair of studies published in JAMA Network Open. People diagnosed with cannabis use disorder (CUD) may face nearly triple the risk of death over five years compared to those without the disorder, according to a large study published Feb. 6. The study, conducted in Ontario, Canada, found that people treated for CUD in hospitals or emergency rooms were 10 times more likely to die by suicide than those in the general population. They were also significantly more likely to die from trauma, drug poisoning and lung cancer, researchers found. A separate study — published Feb. 4 — linked rising cases of psychosis and schizophrenia in Canada to CUD since the country legalized recreational marijuana in 2018. Researchers suspect C.U.D. is even more widespread than the data indicate.  When they analyzed Ontario health records from 106,994 people diagnosed with CUD during a hospital or emergency room visit between 2006 and 2021, researchers found: 3.5% of people with CUD died within five years of treatment, compared to 0.6% of a similar group of people without CUD. CUD patients still had a 2.8 times higher risk of death than the general population even after other risk factors like mental illness, heart disease, cancer and other substance use were considered. Young adults aged 25 to…  read on >  read on >

Los Angeles County residents are still recovering from the devastation of the Palisades and Eaton fires, and new data show that emergency department (ED) visits for wildfire-related issues jumped eight-fold in the days after the fires broke out. In fact, the new data “likely underestimate the prevalence of wildfire-associated ED encounters,” a team led by Emily Kajita of the Los Angeles County Department of Public Health (LACDPH) concludes. Fueled by bone-dry conditions and winds reaching gusts of 100 mph, the Palisades and Eaton fires roared through tens of thousands of acres, destroying more than 16,000 structures and killing 29 people.  The fires took weeks to put out completely and dirtied the air Los Angelenos breathed during that time. Kajita and colleagues looked at LACDPH data on ED encounters occurring in 90% of hospitals across the county. Overall, ED visits actually dropped by 9% in the first six days after the fires broke out, compared to the three weeks prior.   The researchers note that this is in keeping with ED trends during natural disasters generally, as people focus more on moving away from affected areas; schools and businesses are shut down; and many folks take added precautions around their health. However, between Jan. 7 and 12 there was a sharp spike in ED encounters for illnesses and injuries linked directly to the fires.  Rates for…  read on >  read on >

Ahead of this weekend’s Super Bowl, some good news for the athletes: NFL players are largely avoiding opioid-based pain relievers when injuries strike. A new study of data from the 2021 and 2022 seasons finds the National Football League’s efforts to curb addictive opioid use is working, with the drugs comprising less than 3% of all pain meds prescribed.  “Moreover, only 10 percent of NFL athletes received even a single prescription for an opioid during a one-year period,” noted study co-author Dr. Kurt Kroenke, a researcher-clinician at the Regenstrief Institute and Indiana University School of Medicine, in Indianapolis.  “I think there’s been much greater attention to what can be done in the training room for NFL athletes for their injuries and pain that doesn’t rely on medicines,” he added.  Many Americans fall prey to opioid misuse and addiction when they are prescribed the drugs to ease pain from injury or another cause.  Even the toughest athletes can be vulnerable. “Professional football is a very physical sport,” Kroenke said in a Regenstrief news release. “But anyone who watches professional hockey or NBA basketball or big league soccer and even college and high school sports, realizes how these players also are prone to injuries and pain.” When it comes to pro football players, he added, “there’s always been a concern from a safety and health perspective about…  read on >  read on >