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The U.S. Food and Drug Administration on Thursday finalized the elimination of certain restrictions that prevented healthy gay and bisexual men from donating blood. Instead of requiring men who have sex with men or the women who have sex with them to abstain for sexual contact for three months, the FDA has created an individual risk assessment for all donors. These questions are meant to reduce the risk of transfusion-transmitted HIV. “The FDA has worked diligently to evaluate our policies and ensure we had the scientific evidence to support individual risk assessment for donor eligibility while maintaining appropriate safeguards to protect recipients of blood products. The implementation of these recommendations will represent a significant milestone for the agency and the LGBTQI+ community,” Dr. Peter Marks, director of the FDA’s Center for Biologics Evaluation and Research, said in an agency news release. “The FDA is committed to working closely with the blood collection industry to help ensure timely implementation of the new recommendations, and we will continue to monitor the safety of the blood supply once this individual risk-based approach is in place,” Marks added. These policies are in alignment with what already happens in some other countries, including the United Kingdom and Canada, according to the FDA. LGBTQ advocates said the decision was much needed. “The FDA’s decision to follow science and issue new recommendations…  read on >  read on >

The first U.S. cases of drug-resistant ringworm infection have been reported in New York City. The cases of two women with highly contagious skin infections caused by Trichophyton indotineae are reported in the May 12 issue of the U.S. Centers for Disease Control and Prevention’s Morbidity and Mortality Weekly Report . The fungus causes widespread, very itchy, and very hard-to-treat tinea infections. (Tinea is also known as ringworm, which can be misleading since no actual worm is involved.) “These are the first reported cases in the United States, but the infection is now spanning the globe,” said researcher Dr. Avrom Caplan, a dermatologist at NYU Langone Medical Center in New York City. It has been spreading widely in India over the last decade and was termed “indotineae” in a report of two 2020 cases, he noted. “The name should not imply that it is only in India,” Caplan said. “We may see more of this infection over time.” The infection can be transmitted by direct contact; by contact with particles of dead skin, nails and hair shed by the host, usually animals and pets; or by contact with fungal spores. The infection is easily spread from person to person. Caplan said doctors should be aware of this infection and that topical antifungal creams aren’t going to be enough to treat it. “We also know that…  read on >  read on >

An asthma attack can literally leave you gasping for breath, so having treatments that relax your airways is critical. Asthma strikes nearly 8% of Americans, according to the U.S. Centers for Disease Control and Prevention, so if you have asthma, you are not alone. A chronic condition, asthma occurs when the airways become inflamed and narrow, which hinders airflow. “The prevention of asthma as a condition is quite difficult. What you can prevent is the frequency and severity of attacks by the use of regular treatment,” Dr. John Costello, a pulmonologist at Mayo Clinic Healthcare in London, said in a recent article. Here, experts discuss the most common asthma treatments that physicians use when creating an individualized treatment plan. Non-medication treatments for asthma Your physician will work with you to develop an individualized treatment plan. It is important to follow this plan diligently and check in with your physician regularly. Avoid triggers: Because asthma is triggered by many things in the environment, one of the most important treatments for asthma does not involve medication, but rather awareness of what those triggers are. It is important for you to keep a journal in which you record when you have an attack and what triggered it. By noticing what your individual triggers are, you are more prepared to avoid them in the future. According to the Allergy…  read on >  read on >

A medication to treat agitation in Alzheimer’s patients now has approval from the U.S. Food and Drug Administration. The FDA gave supplemental approval to Otsuka Pharmaceutical Company Ltd., and Lundbeck Inc. for Rexulti (brexpiprazole) oral tablets on Thursday. Rexulti is the first FDA-approved treatment for these symptoms. “Agitation is one of the most common and challenging aspects of care among patients with dementia due to Alzheimer’s disease. ‘Agitation’ can include symptoms ranging from pacing or restlessness to verbal and physical aggression,” said Dr. Tiffany Farchione, director of the division of psychiatry in the FDA’s Center for Drug Evaluation and Research. “These symptoms are leading causes of assisted living or nursing home placement and have been associated with accelerated disease progression,” she added in an agency news release. The approval followed two 12-week studies. Participants were between 51 and 90 years of age, and had a probable diagnosis of Alzheimer’s dementia, along with the type, frequency and severity of agitation behaviors that require medication. Patients in the first study received either 1 or 2 milligrams (mg) of Rexulti. In the second study, they received 2 or 3 mg of Rexulti. Over the 12 weeks, researchers looked for a change from baseline in a patient’s Cohen-Mansfield Agitation Inventory (CMAI) score. The inventory is a tool that uses caregivers’ input to rate the frequency of agitation on a…  read on >  read on >

There’s a glimmer of good news when it comes to the mental health of America’s adolescents: Visits to U.S. emergency departments for psychiatric troubles declined among kids aged 12 to 17 by the fall of 2022, compared to a year prior. Overall, mean weekly adolescent emergency department (ED) visits for mental health conditions fell by 11% last fall, compared to higher levels in the fall of 2021, when the pandemic was still keeping many kids out of school and in lockdown at home. According to data compiled by the U.S. Centers for Disease Control and Prevention, similar year-on-year declines were also seen for adolescent ED visits linked to thoughts of suicide (down 12%) and drug overdoses (down 10%). Why the improvement in teens’ mental health? “Many adolescents have returned to prepandemic-like school and community environments, which might have improved social engagement, reduced isolation and supported mental and behavioral health,” wrote a team led by CDC investigator Kayla Anderson. The researchers also believe that “familial stressors” might also have ebbed as kids were released from lockdowns and remote schooling. The report wasn’t all good news, however. Boys seem to be benefiting more than girls, the researchers noted, and ED visits for mental health conditions “remain similar to or higher than already concerningly high prepandemic baselines among females into 2022,” the team reported. There was also one…  read on >  read on >

Fighting is par for the course in professional ice hockey, but a new study raises the question of whether it is shortening some players’ lives. The study, of hundreds of National Hockey League (NHL) players, found that those who were “enforcers” on the ice — that is, did a lot of fighting — tend to die at a younger age and from different causes than their peers. Of 45 players who died during the study period, enforcers were about 10 years younger at their deaths compared to other players. And the causes were disproportionately from suicide, drug overdose, car accidents, or, in two cases, degenerative brain disease. Experts stressed that the findings do not prove that frequent fights on the ice played any role in those players’ deaths. Release of the study comes midway through the second-round of the NHL’s Stanley Cup championship playoffs. The study used fights and time in the penalty box as proxies for players’ exposure to repetitive head impacts. There was no way to tell whether those who died had any brain injury. And even if they did, the researchers said, it would not be possible to draw a straight line between the injury and the cause of death. “This study is just showing associations, not cause and effect,” said lead researcher Dr. Charles Popkin, an orthopedic sports medicine specialist at…  read on >  read on >

People who use a Peloton exercise bike at home should check their model number immediately. A recall of 2 million bikes with the model number PL01 was issued Thursday. People should stop using them immediately because of fall and injury hazards, the U.S. Consumer Product Safety Commission said. The new recall follows reports of seat posts that break and detach from the bike during use. Peloton has received 35 reports of this problem, including 13 involving injuries. The reported injuries include a fractured wrist, cuts and bruises from falling off the bike. Customers who have the recalled bike can contact Peloton for a free seat post and instructions on installing it. The PL01 model number is displayed on the bike’s inside front fork, near the flywheel. The recalled bikes were sold at Dick’s Sporting Goods stores nationwide and online at Onepeloton.com, Amazon.com and Dickssportinggoods.com from January 2018 through May 2023. They retailed for about $1,400. For recall information, contact Peloton toll-free at 866-679-9129 from 6 a.m. to 12 a.m. ET, seven days a week or online. For information on how to request the free seat post and installation instructions, visit onepeloton.com and click “Product Recalls” at the bottom of the page. More information The U.S. National Library of Medicine has tips for avoiding exercise injuries. SOURCE: U.S. Consumer Product Safety Commission, May 11, 2023  read on >

A “peanut patch” worn on the skin may help protect toddlers who have potentially life-threatening peanut allergies, a new clinical trial shows. The patch is a form of immunotherapy, which means it exposes peanut-allergic children to tiny bits of peanut protein over time — with the goal of training the immune system to better tolerate it. In the trial, researchers found that of toddlers who wore the peanut patch every day for a year, two-thirds showed a significant reduction in their sensitivity to peanut protein: They were able to eat the equivalent of one to four peanuts without suffering an allergic reaction. While that might sound like peanuts, experts said that level of tolerance is important. The goal of immunotherapy is to prevent a severe reaction should a child accidentally ingest a small amount of peanut, said Dr. Alkis Togias, of the U.S. National Institute of Allergy and Infectious Diseases. “This is a positive study,” said Togias, who wrote an editorial published with the findings on May 10 in the New England Journal of Medicine. The patch tested in the trial, called Viaskin, is being developed by French biotech company DVB Technologies, which funded the research. It is not yet approved by the U.S. Food and Drug Administration. If it does win approval, Togias said, “I think that would only be a good thing.” An…  read on >  read on >

Poor sleep brought on by sleep apnea may ultimately undermine the brain health of older men and women, new research suggests. The concern stems from a new brain scan investigation that involved 140 sleep apnea patients. “Sleep apnea is a medical condition in which patients … stop breathing during sleep, which can affect their sleep quality by causing multiple arousals and dropping oxygen levels,” said lead study author Dr. Diego Carvalho. He is an assistant professor of neurology at the Mayo Clinic Center for Sleep Medicine in Rochester, Minn. Sleep apnea “has been associated with increased risk of high blood pressure, diabetes, heart attack, stroke, cognitive impairment and dementia,” Carvalho said. And, he noted, it is known to “cause a range of harmful effects in the brain,” as blood pressure and heart rate rise, oxygen levels drop and sleep is disrupted. Importantly, sleep apnea can limit a person’s ability to get and maintain “deep sleep.” Deep sleep, which begins about an hour after falling asleep, is essential to the body’s ability to repair and regenerate tissue, bolster the immune system, and build bone and muscle, according to the Cleveland Clinic. Getting enough of it is, therefore, considered a key indicator of good quality shut-eye. With that in mind, Carvalho and his team set out to see whether the impact of sleep apnea on deep sleep…  read on >  read on >

While the U.S. Veterans Affairs health system has been criticized for long appointment wait times and limited access to specialists, the quality of care and access to a range of surgical services is as good as or better than at non-VA health centers on several measures, new research reveals. “Surgery involves many steps of care,” said lead study author Dr. Mariah Blegen, a fellow in the department of surgery at the University of California, Los Angeles David Geffen School of Medicine. “This updated review is important because it tells us that the veterans at the VA are getting good care. Quality improvement, through the VA National Surgical Quality Improvement Program (VA NSQIP), has been the focus of the VA for several decades and I think this effort is paying off,” Blegen said in a news release from the American College of Surgeons. The findings were published online May 8 in the Journal of the American College of Surgeons. VA NSQIP has helped track millions of surgical cases and improve outcomes, including improved rates of postoperative death and infection, according to the researchers. “The database continues to drive statistically reliable research that can help VA hospitals better assess its surgical outcomes and develop quality improvement programs,” said Dr. Clifford Ko, director of the ACS Division of Research and Optimal Patient Care. After the success of VA…  read on >  read on >