
A subset of people may be at high risk for both psychiatric disorders and for using marijuana, based on their genetics, according to a new study. Researchers from the University of Oslo in Norway have found that some of the genetic variants associated with cannabis use are also linked to psychiatric disorders. “These findings are important as they show that the complex links between cannabis use and these disorders may not only be caused by cannabis use itself, but could also be driven by shared genetic susceptibility,” lead co-author Nadine Parker said in a university news release. The rate of cannabis use is high among patients with disorders linked to psychosis, including schizophrenia and bipolar disorder. Cannabis is a psychoactive drug that can sometimes produces psychotic-like symptoms, according to the study. “This study shows that there is a shared genetic basis underlying our susceptibility to both cannabis use and certain psychiatric disorders,” lead co-author Weiqiu Cheng said in the release. To study this, Parker, Cheng and their colleagues used advanced statistical modeling. They found that a majority of shared variants increased the risk of both cannabis use and developing either schizophrenia or bipolar disorder. Yet, there were some genetic variants with opposing effects that increased the risk of cannabis use while decreasing the risk of the two psychiatric disorders. In some parts of the world,… read on > read on >